Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Jacques Dornand"'
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2007, 75 (12), pp.5916-23. ⟨10.1128/IAI.00931-07⟩
Infection and Immunity, American Society for Microbiology, 2007, 75 (12), pp.5916-23. ⟨10.1128/IAI.00931-07⟩
Brucellais a facultative intracellular pathogen of various mammals and the etiological agent of brucellosis. We recently demonstrated that dendritic cells (DCs), which are critical components of adaptive immunity, are highly susceptible toBrucellainf
Autor:
Zeus Saldaña, Jorge A. Girón, María A. Rendón, Safia Ouahrani-Bettache, Fabiola Avelino, Jacques Dornand, Elsa I Castañeda-Roldán
Publikováno v:
Cellular Microbiology. 8:1877-1887
Summary Brucella is an invasive organism that multiplies and survives within eukaryotic cells. The brucellae are able to adhere to the surface of cultured epithelial cells, a mechanism that may facilitate penetration and dissemination to other host t
Autor:
Eugénie Bassères, Stephan Köhler, Jacques Dornand, Jean-Pierre Liautard, Véronique Jubier-Maurin, Séverine Loisel-Meyer, María Pilar Jiménez de Bagüés
Publikováno v:
Infection and Immunity. 74:1973-1976
A mutant of Brucella suis bearing a Tn 5 insertion in norD , the last gene of the operon norEFCBQD , encoding nitric oxide reductase, was unable to survive under anaerobic denitrifying conditions. The norD strain exhibited attenuated multiplication w
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2005, 73 (12), pp.8418-24. ⟨10.1128/IAI.73.12.8418-8424.2005⟩
Infection and Immunity, American Society for Microbiology, 2005, 73 (12), pp.8418-24. ⟨10.1128/IAI.73.12.8418-8424.2005⟩
Bacteria from theBrucellagenus are able to survive and proliferate within macrophages. Because they are phylogenetically closely related to macrophages, myeloid dendritic cells (DCs) constitute potential targets forBrucellabacteria. Here we report th
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2005, 73 (5), pp.3178-83. ⟨10.1128/IAI.73.5.3178-3183.2005⟩
Infection and Immunity, American Society for Microbiology, 2005, 73 (5), pp.3178-83. ⟨10.1128/IAI.73.5.3178-3183.2005⟩
By comparing smooth wild-typeBrucellaspp. to their rough mutants, we show that the LPS O chain restricted the activation of the ERK1/2 and p38 mitogen-activated protein kinase (MAPK) pathways, thus preventing the synthesis of immune mediators that re
Autor:
Maria-Pilar, Jimenez de Bagues, Jimenez de Bagues, Maria-Pilar, Sherri, Dudal, Jacques, Dornand, Antoine, Gross
Publikováno v:
Clinical Immunology
Clinical Immunology, Elsevier, 2005, 114 (3), pp.227-38. ⟨10.1016/j.clim.2004.07.010⟩
Clinical Immunology, Elsevier, 2005, 114 (3), pp.227-38. ⟨10.1016/j.clim.2004.07.010⟩
Brucellosis is a worldwide human zoonosis caused by intracellular bacteria of the genus Brucella. Virulence factors play an important role in allowing Brucella infection and proliferation within macrophages. Brucella enters macrophages through lipid
Autor:
Fabiola Avelino-Flores, Elsa I Castañeda-Roldán, Jorge A. Girón, Monique Dall'Agnol, Lilia Cedillo, Jacques Dornand, Enrique Freer
Publikováno v:
Cellular Microbiology. 6:435-445
The basis for the interaction of Brucella species with the surface of epithelial cells before migration in the host within polymorphonuclear leucocytes is largely unknown. Here, we studied the ability of Brucella abortus and Brucella melitensis to ad
Autor:
Elsa I Castañeda-Roldán, Jean-Pierre Liautard, Annie Terraza, Virginie Lafont, Jane Oliaro, Jacques Dornand
Publikováno v:
Infection and Immunity. 72:2303-2311
Brucellaspp. are facultative intracellular bacteria that can establish themselves and cause chronic disease in humans and animals. NK cells play a key role in host defense. They are implicated in an early immune response to a variety of pathogens. Ho
Publikováno v:
Microbial Pathogenesis
Microbial Pathogenesis, Elsevier, 2004, 36 (2), pp.75-82. ⟨10.1016/j.micpath.2003.09.003⟩
Microbial Pathogenesis, Elsevier, 2004, 36 (2), pp.75-82. ⟨10.1016/j.micpath.2003.09.003⟩
In mice, nitric oxide (NO) production by inducible NO synthase (iNOS), is a component of the control of Brucella infection. In humans, the involvement of iNOS in infection is still a matter of debate. Based on in vitro experiments, it was recently po
Autor:
Diethard Gemsa, H Sprenger, Barry Shaw, Adrian Robins, Andreas Kaufmann, Michael Rittig, Bruno Rouot, Jacques Dornand, Vincent Foulongne
Publikováno v:
Journal of Leukocyte Biology. 74:1045-1055
Virulence of the intracellular pathogen Brucella for humans is mainly associated with its lipopolysaccharide (LPS) phenotype, with smooth LPS phenotypes generally being virulent and rough ones not. The reason for this association is not quite underst