Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jacques C. Mbongue"'
Autor:
Dequina A. Nicholas, Jacques C. Mbongue, Darysbel Garcia-Pérez, Dane Sorensen, Heather Ferguson Bennit, Marino De Leon, William H. R. Langridge
Publikováno v:
Immuno, Vol 4, Iss 1, Pp 91-107 (2024)
Around 285 million people worldwide currently have type 2 diabetes and it is projected that this number will be surpassed by 2030. Therefore, it is of the utmost importance to enhance our comprehension of the disease’s development. The regulation o
Externí odkaz:
https://doaj.org/article/38fba84317d249d6bee16decbb9ae187
Publikováno v:
Immuno, Vol 3, Iss 2, Pp 217-227 (2023)
The 19th century saw the development of vaccines, which were biological preparations designed to enhance immunity against specific diseases. Edible vaccines function by stimulating both systemic and mucosal immune responses against foreign pathogens,
Externí odkaz:
https://doaj.org/article/5675089225204db1b6b5b52ff7abb41c
Publikováno v:
Immuno, Vol 2, Iss 3, Pp 482-500 (2022)
Bacterial lipopolysaccharides (LPS), also referred to as endotoxins, are major outer surface membrane components present on almost all Gram-negative bacteria and are major determinants of sepsis-related clinical complications including septic shock.
Externí odkaz:
https://doaj.org/article/35082e60567e4c5cb4f9a0cacc23c442
Autor:
Jacques C. Mbongue, Ali Alhoshani, Jeffrey Rawson, Pablo A. Garcia, Nelson Gonzalez, Kevin Ferreri, Fouad Kandeel, Mohamed I. Husseiny
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Type 1 diabetes (T1D) arises secondary to immune-driven destruction of pancreatic β-cells and manifests as insulin-deficient hyperglycemia. We showed that oral vaccination with live attenuated Salmonella, which simultaneously delivers autoantigens a
Externí odkaz:
https://doaj.org/article/4415d35167b14275bf9e4df46af04ba2
Autor:
Jacques C. Mbongue, Jeffrey Rawson, Pablo A. Garcia, Nelson Gonzalez, Jacob Cobb, Fouad Kandeel, Kevin Ferreri, Mohamed I. Husseiny
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoimmune diseases such as type 1 diabetes (T1D) involve the loss of regulatory mechanisms resulting in increased tissue-specific cytotoxicity. The result is destruction of pancreatic insulin-producing β-cells and loss of glucose homeostasis. We ar
Externí odkaz:
https://doaj.org/article/15614e04a26a48d782330488da2c5f58
Autor:
Jacques C. Mbongue, Dequina A. Nicholas, Timothy W. Torrez, Nan-Sun Kim, Anthony F. Firek, William H.R. Langridge
Publikováno v:
Vaccines, Vol 3, Iss 3, Pp 703-729 (2015)
Indoleamine 2, 3-dioxygenase (IDO) is the first and rate limiting catabolic enzyme in the degradation pathway of the essential amino acid tryptophan. By cleaving the aromatic indole ring of tryptophan, IDO initiates the production of a variety of try
Externí odkaz:
https://doaj.org/article/996e5456eb0541558420f62c530cb9fd
Autor:
Pablo A. Garcia, Nelson Gonzalez, Fouad Kandeel, Mohamed I. Husseiny, Jacob Cobb, Kevin Ferreri, Jacques C. Mbongue, Jeffrey Rawson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoimmune diseases such as type 1 diabetes (T1D) involve the loss of regulatory mechanisms resulting in increased tissue-specific cytotoxicity. The result is destruction of pancreatic insulin-producing β-cells and loss of glucose homeostasis. We ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a37e44e1bcdc3ad46985d6c5a5ee17
https://www.frontiersin.org/article/10.3389/fimmu.2019.00320/full
https://www.frontiersin.org/article/10.3389/fimmu.2019.00320/full
Autor:
Ayelet Lenz, Jeffrey Rawson, Mohamed I. Husseiny, Fouad Kandeel, Kevin Ferreri, Weiting Du, Jacques C. Mbongue
Publikováno v:
Vaccine. 36(52)
We previously reported the development of an oral vaccine for diabetes based on live attenuated Salmonella-expressing preproinsulin (PPI) as the autoantigen. When combined with host cell-expressed TGFβ, the vaccine prevented the onset of diabetes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c5d70aa315be2ad14bf92b6a1e7995
https://pubmed.ncbi.nlm.nih.gov/30416020
https://pubmed.ncbi.nlm.nih.gov/30416020
Autor:
Anthony Firek, Nan-Sun Kim, Timothy W. Torrez, William H. R. Langridge, Jacques C. Mbongue, Dequina A. Nicholas
Publikováno v:
Vaccines, Vol 3, Iss 3, Pp 703-729 (2015)
Vaccines
Vaccines
Indoleamine 2, 3-dioxygenase (IDO) is the first and rate limiting catabolic enzyme in the degradation pathway of the essential amino acid tryptophan. By cleaving the aromatic indole ring of tryptophan, IDO initiates the production of a variety of try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204c3c3c789a83baee99909a3f34c943
http://www.mdpi.com/2076-393X/3/3/703
http://www.mdpi.com/2076-393X/3/3/703
Publikováno v:
Frontiers in Immunology
Dendritic cells (DCs) are the dominant class of antigen-presenting cells in humans and are largely responsible for the initiation and guidance of innate and adaptive immune responses involved in maintenance of immunological homeostasis. Immature dend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067f52fbcd7521241b84cc910beff6a3
https://pubmed.ncbi.nlm.nih.gov/28396662
https://pubmed.ncbi.nlm.nih.gov/28396662