Zobrazeno 1 - 10 of 71 pro vyhledávání: '"Jacques Boutet de Monvel"'
1
Akademický článek
Extracting multiple surfaces from 3D microscopy images in complex biological tissues with the Zellige software tool
Autor: Céline Trébeau, Jacques Boutet de Monvel, Gizem Altay, Jean-Yves Tinevez, Raphaël Etournay
Publikováno v: BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Efficient tools allowing the extraction of 2D surfaces from 3D-microscopy data are essential for studies aiming to decipher the complex cellular choreography through which epithelium morphogenesis takes place during development. M
Externí odkaz: https://doaj.org/article/26b02e3392e84459a0be11554a8fb9a3
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2
Akademický článek
The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
Autor: Charlotte Calvet, Thibault Peineau, Najate Benamer, Maxence Cornille, Andrea Lelli, Baptiste Plion, Ghizlène Lahlou, Julia Fanchette, Sylvie Nouaille, Jacques Boutet de Monvel, Amrit Estivalet, Philippe Jean, Vincent Michel, Martin Sachse, Nicolas Michalski, Paul Avan, Christine Petit, Didier Dulon, Saaid Safieddine
Publikováno v: iScience, Vol 25, Iss 12, Pp 105628- (2022)
Summary: Hearing depends on fast and sustained calcium-dependent synaptic vesicle fusion at the ribbon synapses of cochlear inner hair cells (IHCs). The implication of the canonical neuronal SNARE complex in this exocytotic process has so far remaine
Externí odkaz: https://doaj.org/article/b93b8ca16eb54c7397c900ea371497c5
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3
Akademický článek
Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses
Autor: Nicolas Michalski, Juan D Goutman, Sarah Marie Auclair, Jacques Boutet de Monvel, Margot Tertrais, Alice Emptoz, Alexandre Parrin, Sylvie Nouaille, Marc Guillon, Martin Sachse, Danica Ciric, Amel Bahloul, Jean-Pierre Hardelin, Roger Bryan Sutton, Paul Avan, Shyam S Krishnakumar, James E Rothman, Didier Dulon, Saaid Safieddine, Christine Petit
Publikováno v: eLife, Vol 6 (2017)
Hearing relies on rapid, temporally precise, and sustained neurotransmitter release at the ribbon synapses of sensory cells, the inner hair cells (IHCs). This process requires otoferlin, a six C2-domain, Ca2+-binding transmembrane protein of synaptic
Externí odkaz: https://doaj.org/article/0573827227564a46bbf876f5400e53e1
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4
Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model
Autor: Omar Akil, Saaid Safieddine, Jacques Boutet de Monvel, Charlotte Calvet, Frank M. Dyka, Ghizlene Lahlou, Sylvie Nouaille, Jean-Pierre Hardelin, Paul Avan, Alice Emptoz, Christine Petit, William W. Hauswirth, Lawrence R. Lustig
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (10), pp.4496-4501. ⟨10.1073/pnas.1817537116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (10), pp.4496-4501. ⟨10.1073/pnas.1817537116⟩
Significance In humans, inner ear development is completed in utero, with hearing onset at ∼20 weeks of gestation. However, genetic forms of congenital deafness are typically diagnosed during the neonatal period. Gene therapy approaches in animal m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a59eb91d9ac9543df3524f03209acd9
https://doi.org/10.1073/pnas.1817537116
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6
Usher syndrome type 1–associated cadherins shape the photoreceptor outer segment
Autor: Amrit Estivalet, Asadollah Aghaie, Aziz El-Amraoui, Cataldo Schietroma, Karine Parain, José-Alain Sahel, Muriel Perron, Christine Petit, Jacques Boutet de Monvel, Serge Picaud
Publikováno v: The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, 2017, 216 (6), pp.1849-1864. ⟨10.1083/jcb.201612030⟩
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (6), pp.1849-1864. ⟨10.1083/jcb.201612030⟩
Usher syndrome type 1 (USH1) causes combined hearing and sight defects, but USH1 protein function in the retina is unclear. Schietroma et al. use Xenopus to model the deficiency in two USH1 proteins—protocadherin-15 and cadherin-23—and identify c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec76f9a3e05cbdd9cdadd07cf329245
https://doi.org/10.1083/jcb.201612030
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7
Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells
Autor: Elise Pepermans, Vincent Michel, Alain Aghaie, Jean-Pierre Hardelin, Amel Bahloul, Sylvie Nouaille, Isabelle Perfettini, Patrick England, Christine Petit, Jacques Boutet de Monvel, Florent Delhommel, Nicolas Wolff
Publikováno v: Scientific Reports
Scientific reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.16430. ⟨10.1038/s41598-020-73158-1⟩
Scientific Reports, 2020, 10 (1), pp.16430. ⟨10.1038/s41598-020-73158-1⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
International audience; The hair bundle of cochlear hair cells is the site of auditory mechanoelectrical transduction. It is formed by three rows of stiff microvilli-like protrusions of graduated heights, the short, middle-sized, and tall stereocilia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626c14b4c655352f8fbe35c76e5be781
https://pubmed.ncbi.nlm.nih.gov/33009420
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8
DNABarcodeCompatibility: an R-package for optimizing DNA-barcode combinations in multiplex sequencing experiments
Autor: Céline Trébeau, Christine Petit, Fabienne Wong Jun Tai, Jacques Boutet de Monvel, Raphaël Etournay
Publikováno v: Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2019, ⟨10.1093/bioinformatics/bty1030⟩
Bioinformatics, 2019, ⟨10.1093/bioinformatics/bty1030⟩
Summary Using adequate DNA barcodes is essential to unambiguously identify each DNA library within a multiplexed set of libraries sequenced using next-generation sequencers. We introduce DNABarcodeCompatibility, an R-package that allows one to design
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3b3be971d72d3b1fb47c4b9e6c2c11
https://hal-pasteur.archives-ouvertes.fr/pasteur-02175109/document
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10
Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G
Autor: Alice, Emptoz, Vincent, Michel, Andrea, Lelli, Omar, Akil, Jacques, Boutet de Monvel, Ghizlene, Lahlou, Anaïs, Meyer, Typhaine, Dupont, Sylvie, Nouaille, Elody, Ey, Filipa, Franca de Barros, Mathieu, Beraneck, Didier, Dulon, Jean-Pierre, Hardelin, Lawrence, Lustig, Paul, Avan, Christine, Petit, Saaid, Safieddine
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (36), pp.9695-9700. ⟨10.1073/pnas.1708894114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (36), pp.9695-9700. ⟨10.1073/pnas.1708894114⟩
International audience; Our understanding of the mechanisms underlying inherited forms of inner ear deficits has considerably improved during the past 20 y, but we are still far from curative treatments. We investigated gene replacement as a strategy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::de91960ac6c0a3018d14421e98a3a695
https://hal.science/hal-01661148
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