Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Jacques Bolard"'
Publikováno v:
Journal of Fluorescence. 21:831-834
Fluorescence has recently been applied to the analysis of the molecular organization state of the polyene antibiotic amphotericin B (AmB) in solution or in lipid membranes. The polyene chain of AmB monomer gives rise to two fluorescence emissions; S(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e5dc39055913c9b1e4c5caa0fb9d68
https://doi.org/10.1007/s10895-010-0768-0
https://doi.org/10.1007/s10895-010-0768-0
Publikováno v:
Journal of Antimicrobial Chemotherapy. 63:921-927
Objectives: Based on the assertion that fluorescence spectroscopy detects dimers of the polyene antibiotic amphotericin B (AmB), this technique was recently proposed to analyse the interaction of the drug with cell membranes. However, contradictory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332186ec0bef0a7e2180f279b11cdd20
https://doi.org/10.1093/jac/dkp059
https://doi.org/10.1093/jac/dkp059
Publikováno v:
Bioelectrochemistry. 74:2-8
The positively charged polyene molecule amphotericin B 3-dimethylaminopropylamide (AMA) is an efficient agent for the delivery of antisense oligodeoxyribonucleotides (ODN) into target cells. In the present study, bilayer lipid membrane (BLM) conducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9744dd30705a551d526c71ae84a0340a
https://doi.org/10.1016/j.bioelechem.2007.08.001
https://doi.org/10.1016/j.bioelechem.2007.08.001
Publikováno v:
Medical Mycology. 45:525-533
Flow cytometry light scattering was used to monitor size increase of Candida albicans (isolate ATCC 10231) cells in the presence or absence of the antifungal drug amphotericin B (AmB). This non-invasive and descriptive method allowed for the differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec21705521a2d96e293c2ba5cb75e20a
https://doi.org/10.1080/13693780701487821
https://doi.org/10.1080/13693780701487821
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1760:973-979
The toxicity of the antifungal polyene antibiotic amphotericin B (AMB) has been related to its low solubility, more specifically to a self-associated form termed toxic aggregate. In addition, AMB in aqueous medium gives rise to concentration, ionic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad06bd856a94af1c47a8466174108f1b
https://doi.org/10.1016/j.bbagen.2006.02.004
https://doi.org/10.1016/j.bbagen.2006.02.004
Autor:
Edward Borowski, Joanna Szlinder-Richert, Barbara Cybulska, Jolanta Grzybowska, Jacques Bolard
Publikováno v:
Il Farmaco. 59:289-296
Amphotericin B (AMB) derivative, N-methyl-N-D-fructosyl amphotericin B methyl ester (MFAME) retains the broad antifungal spectrum and potency of the parent antibiotic, whereas its toxicity towards mammalian cells is reduced by about two orders of mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab50e0cbfd153202ce2b4ddcd725ded
https://doi.org/10.1016/j.farmac.2003.12.007
https://doi.org/10.1016/j.farmac.2003.12.007
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1464(2):299-308
Antisense strategy requires efficient systems for the delivery of oligodeoxyribonucleotides (ODN) into target cells. Cationic amphiphiles have shown good efficiency in vitro and a lot of attention is currently paid to their interaction with nucleic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f16ff12f5d819d60855b5f807eca5a
Autor:
Carsten Engelmann, Helena Nagy, Yves Panis, Bertrand Diquet, Olivier Soubrane, Monique Fabre, David Klatzmann, Didier Houssin, Jacques Bolard
Publikováno v:
Human Gene Therapy. 10:1545-1551
Suicide gene therapy based on ganciclovir (GCV) metabolism by transgene herpes simplex thymidine kinase (HSV-1 TK) has been used to selectively kill proliferating cells in clinical settings such as cancer, vascular restenosis, and immunological disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a9e46a87db3b4fdd5dafd5faf10f7c
https://doi.org/10.1089/10430349950017879
https://doi.org/10.1089/10430349950017879
Publikováno v:
Biospectroscopy. 2:1-8
Amphotericin B (AmB) is a macrolide polyene antibiotic with an asymmetrical distribution of hydrophobic and hydrophilic groups (Fig. 1). Due to this chemical structure AmB is poorly soluble water as well as in many organic solvent [1]. Amphotericin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9916631df22bf6fdbb5711142dbb1f5a
https://doi.org/10.1002/(sici)1520-6343(1996)2:1<1::aid-bspy1>3.0.co
https://doi.org/10.1002/(sici)1520-6343(1996)2:1<1::aid-bspy1>3.0.co
Publikováno v:
Journal of Antimicrobial Chemotherapy. 42:779-785
Heat-induced 'superaggregation' of deoxycholate-amphotericin B (AmB-DOC, Fungizone) was shown previously to reduce the in-vitro toxicity of this antifungal agent. We compared AmB-DOC with the formulation obtained by heating the commercial form (Fungi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47983e78f4be037711b85cde4b2e0027
https://doi.org/10.1093/jac/42.6.779
https://doi.org/10.1093/jac/42.6.779