Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Jacques Benveniste"'
Autor:
L. Moizo, J.-P. Laigneau, André Bado, M. J. M. Lewin, Iradj Sobhani, Jacques Benveniste, Y. Denizot, Christian L. Laboisse
Publikováno v:
European Journal of Clinical Investigation. 26:53-58
The authors have previously reported that platelet-activating factor (PAF), a phospholipid mediator with potent proinflammatory activities, is produced in the gastric mucosa and stimulates gastric acid secretion in humans and animals. In the present
Autor:
Daniel Couturier, Angelo A. Izzo, Jean Pierre Martinolle, N. Vidon, Stanislas Chaussade, Rosine Guimbaud, Jacques Benveniste
Publikováno v:
Digestive Diseases and Sciences. 40:2635-2640
PAF-acether (PAF) is a phospholipid synthesized by numerous inflammatory cells. PAF can produce several pathological changes in various organs, especially in the colon. In animals PAF causes colonic ulceration and inflammation, which are similar to t
Autor:
Elisabeth Davenas, Olivier Pellegrini, Yves Manuel, Laurence Morin, Jacques Benveniste, Yolène Thomas, George Th. Tsangaris
Publikováno v:
European Journal of Pharmacology: Environmental Toxicology and Pharmacology. 270:221-228
We previously showed in a human T cell line (CEM-C12 cells) that Cd2+ induced gene expression of stress proteins, metallothionein-IIA and heat shock protein 70 in a time- and dose-dependent manner. In the present study, CEM-C12 cells were pretreated
Autor:
Olivier Pellegrini, George Th. Tsangaris, Yolène Thomas, Yves Manuel, Bouchra El Azzouzi, Jacques Benveniste
Publikováno v:
Toxicology. 88:127-139
Cadmium, a potent toxic metal, poses a serious environmental threat but the mechanisms of its toxicity remain unclear. In the present study, we investigated the nature of cadmium-induced cell death in the human T cell line CEM-C12. Cadmium was time-
Publikováno v:
Lipids. 28:193-199
Intact washed human platelets aggregated in response to paf-acether (paf) and did not metabolize [3H]paf at concentrations up to 10 nM. However, when platelets were lysed by exposure to pH 9.5, resulting in 37.5±2.5% (mean ±SD, n=3) lactic dehydrog
Autor:
Miguel J.M. Lewin, C. Vissuzaine, Michel Mignon, Jacques Benveniste, I. Sobhani, Y. Denizot, J. Vatier
Publikováno v:
Digestive Diseases and Sciences. 37:1583-1592
Platelet-activating factor (PAF) has been implicated in the pathogenesis of acute inflammatory and ulcerative diseases of the upper gastrointestinal tract. In the present study, we compared the gastric output of PAF and its precursors with gastric ac
Autor:
Nathalie Nathan, S. Chaussade, N. Cherouki, Jean-Frederic Colombel, Marie-Jeanne Bossant, Y. Denizot, Jacques Benveniste, D. Couturier
Publikováno v:
Digestive Diseases and Sciences. 37:432-437
PAF-acether (PAF) is a phospholipid mediator with potent biological effects on the digestive tract. We report the presence of PAF in stool of patients with active Crohn's disease (39.1 +/- 13.5 ng/g of stool, mean +/- SEM, N = 19) and its absence in
Autor:
Pierre Hautefeuille, Y. Denizot, Patrice Valleur, Jacques Nicoli, Stanislas Chaussade, Jean Guerre, Pierre Raibaud, Jacques Benveniste, Daniel Couturier
Publikováno v:
Gastroenterology
Gastroenterology, WB Saunders, 1991, 100 (6), pp.1509-1514
Gastroenterology, WB Saunders, 1991, 100 (6), pp.1509-1514
Platelet-activating factor is an endogenous phospholipid produced by a wide variety of inflammatory cells. Platelet-activating factor induces severe pathological changes in various organs and, among numerous potent effects, causes bowel necrosis. Pou
Autor:
Corinne Hiéblot, Jacques Benveniste, Claude Burtin, Francis Beauvais, Béatrice Descours, Béatrice Bidet
Publikováno v:
Journal of Allergy and Clinical Immunology. 87:1020-1028
Human basophil activation was demonstrated by histamine release (HR) and by the decrease of the toluidine blue-positive basophils (TB + ). In four experimental systems, TB + number decreased in the absence of HR (1) in basophils from atopic subjects
Publikováno v:
International Immunology. 3:1157-1163
It was recently shown that paf-acether (paf) synthesized in different cell types remains partly cell-associated. In the present work, we tested the hypothesis that cell-associated paf might in fact remain exposed on the external plasma membrane and b