Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jacques A Nunes"'
1
Akademický článek
Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors
Autor: Fabrice Barlesi, Laurent Gorvel, Daniel Olive, Clemence Demerle, Laurent Greillier, Sonia Pastor, Geoffrey Guittard, Jacques A Nunes, Marielle Mello, Clara Degos, Ana Zarubica, Fabien Angelis, Frédéric Fiore, Bernard Malissen, Hervé Luche
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Tumor necrosis factor superfamily member 14 (TNFRSF14)/herpes virus entry mediator (HVEM) is the ligand for B and T lymphocyte attenuator (BTLA) and CD160-negative immune co-signaling molecules as well as viral proteins. Its expression is
Externí odkaz: https://doaj.org/article/fdfc15c4c1eb4b6cb203ba727e691a4f
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2
Akademický článek
Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets
Autor: Pierre-Louis Bernard, Vladimir Laletin, Cathy Costa Da Silva, Geoffrey Guittard, Jacques A Nunes
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Immunotherapy strategies aim to mobilize immune defenses against tumor cells by targeting mainly T cells. Co‐inhibitory receptors or immune checkpoints (ICPs) (such as PD-1 and CTLA4) can limit T cell receptor (TCR) signal propagation in T cells. A
Externí odkaz: https://doaj.org/article/6f47c8ca700c484c8c819cd5fbecc457
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3
Akademický článek
An emerging role for PI5P in T cell biology
Autor: Jacques A Nunes, Geoffrey eGuittard
Publikováno v: Frontiers in Immunology, Vol 4 (2013)
Phosphoinositides are critical regulators in cell biology. Phosphatidylinositol 4,5-bisphosphate, also known as PI(4,5)P2 or PIP2, was the first variety of phosphoinositide to enter in the T cell signaling scene. Phosphatidylinositol bis-phosphates a
Externí odkaz: https://doaj.org/article/d483ae46d3014f21815653926d50057f
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4
Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets
Autor: Vladimir Laletin, Pierre-Louis Bernard, Cathy Costa da Silva, Geoffrey Guittard, Jacques A Nunes
Publikováno v: Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 2023, 11 (5), pp.e005845. ⟨10.1136/jitc-2022-005845⟩
International audience; Immunotherapy strategies aim to mobilize immune defenses against tumor cells by targeting mainly T cells. Co‐inhibitory receptors or immune checkpoints (ICPs) (such as PD-1 and CTLA-4) can limit T cell receptor (TCR) signal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ef1179697959d5e16f533176b689a0
https://hal-amu.archives-ouvertes.fr/hal-04114285
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5
CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression
Autor: Laurys Boudin, Alexandre De Nonneville, Pascal Finetti, Geoffrey Guittard, Jacques A. Nunes, Daniel Birnbaum, Emilie Mamessier, François Bertucci
Publikováno v: Cancers
Cancers, 2022, 14 (14), pp.3356. ⟨10.3390/cancers14143356⟩
Cancers; Volume 14; Issue 14; Pages: 3356
Strategies are being explored to increase the efficiency of immune checkpoint inhibitors (ICIs) targeting PD1/PDL1 in triple-negative breast cancer (TNBC), including combination with therapies inhibiting intracellular immune checkpoints such as CISH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a48e4670e9ee21452f6d092c3ac1e0a
https://hal.science/hal-03765362/document
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7
Dissertation/ Thesis
Mobile marketing: novos usos do sms no mix promocional de marketing
Autor: Vaz, Jacques Chicourel Nunes
Publikováno v: Repositório Institucional da UFBAUniversidade Federal da BahiaUFBA.
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Externí odkaz: http://www.repositorio.ufba.br/ri/handle/ri/8094
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8
Dissertation/ Thesis
A ocupação do solo e o ordenamento dos recursos hídricos sub-bacia do Rio D'Una e complexo lagunar
Autor: Jacques, Gustavo Nunes
Publikováno v: Repositório Institucional da UFSCUniversidade Federal de Santa CatarinaUFSC.
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.
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Externí odkaz: http://repositorio.ufsc.br/handle/123456789/101986
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9
Akademický článek
Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells.
Autor: Besma Aouar, Denisa Kovarova, Sebastien Letard, Albert Font-Haro, Jonathan Florentin, Jan Weber, David Durantel, Laurence Chaperot, Joel Plumas, Katerina Trejbalova, Jiri Hejnar, Jacques A Nunès, Daniel Olive, Patrice Dubreuil, Ivan Hirsch, Ruzena Stranska
Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0156063 (2016)
Crosslinking of regulatory immunoreceptors (RR), such as BDCA-2 (CD303) or ILT7 (CD85g), of plasmacytoid dendritic cells (pDCs) efficiently suppresses production of type-I interferon (IFN)-α/β and other cytokines in response to Toll-like receptor (
Externí odkaz: https://doaj.org/article/31bcf670f149405b9ee89d6a63e165cf
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