Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Jacques, Van Snick"'
Autor:
Junhui Hu, Ping Tan, Moe Ishihara, Nicholas A. Bayley, Shiruyeh Schokrpur, Jeremy G. Reynoso, Yangjun Zhang, Raymond J. Lim, Camelia Dumitras, Lu Yang, Steven M. Dubinett, Parmjit S. Jat, Jacques Van Snick, Jiaoti Huang, Arnold I. Chin, Robert M. Prins, Thomas G. Graeber, Hua Xu, Lily Wu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Loss of function of the von Hippel-Lindau (VHL) tumor suppressor gene is a hallmark of clear cell renal cell carcinoma (ccRCC). The importance of heterogeneity in the loss of this tumor suppressor has been under reported. To study the impact
Externí odkaz:
https://doaj.org/article/7fbb896806994806aeb3daa83568734f
Autor:
Mégane Nascimento, Sarah Huot-Marchand, Manoussa Fanny, Marjolène Straube, Marc Le Bert, Florence Savigny, Lionel Apetoh, Jacques Van Snick, Fabrice Trovero, Mathias Chamaillard, Valérie F. J. Quesniaux, Bernhard Ryffel, Philippe Gosset, Aurélie Gombault, Nicolas Riteau, Harry Sokol, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chronic obstructive pulmonary disease (COPD) is a major health issue primarily caused by cigarette smoke (CS) and characterized by breathlessness and repeated airway inflammation. NLRP6 is a cytosolic innate receptor controlling intestinal inflammati
Externí odkaz:
https://doaj.org/article/a7d159a73b8e40fbaeb58a9775e4aac6
Autor:
Mohamed F. Mandour, Pyone Pyone Soe, Anne-Sophie Castonguay, Jacques Van Snick, Jean-Paul Coutelier
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
IntroductionNatural prevention of cancer development depends on an efficient immunosurveillance that may be modulated by environmental factors, including infections. Innate lymphoid cytotoxic cells have been shown to play a major role in this immunos
Externí odkaz:
https://doaj.org/article/5fd35efe2a654c5caf27f0cf3f14b609
Autor:
Aditi Gupta, Sadna Budhu, Kelly Fitzgerald, Rachel Giese, Adam O. Michel, Aliya Holland, Luis Felipe Campesato, Jacques van Snick, Catherine Uyttenhove, Gerd Ritter, Jedd D. Wolchok, Taha Merghoub
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Gupta et al. demonstrate that targeting isoform-specific TGFβ leads to an increase in the anti-tumor response when compared to pan-TGFβ inhibition, due to enhanced CD8 T cell function. The authors also report that combining TGFβ inhibition with im
Externí odkaz:
https://doaj.org/article/ed988a10eff742c391e7da0374286113
Autor:
Mohamed F. Mandour, Pyone Pyone Soe, Catherine Uyttenhove, Jacques Van Snick, Etienne Marbaix, Jean-Paul Coutelier
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background Viral infections can reduce early cancer development through enhancement of cancer immunosurveillance. This study was performed to analyse this effect of viral infection in a mouse model of solid tumor. Methods The experimental mo
Externí odkaz:
https://doaj.org/article/aa131a45d891400d842aa29ce1cbd298
Autor:
Taha Merghoub, Sadna Budhu, Luis Felipe Campesato, Aditi Gupta, Catherine Uyttenhove, Aliya Holland, Kelly Fitzgerald, Rachel Giese, Adam Michel, Jacques Van Snick, Gerd Ritter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/b7686bae70e5419d9cb92be4956f038f
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Transforming growth factor-β (TGFβ) is emerging as a promising target for cancer therapy, given its ability to promote progression of advanced tumors and to suppress anti-tumor immune responses. However, TGFβ also plays multiple roles i
Externí odkaz:
https://doaj.org/article/d28bf02dc40c434ab23c04a1d7f2362e
Autor:
Carl De Trez, Benoit Stijlemans, Viki Bockstal, Jennifer Cnops, Hannelie Korf, Jacques Van Snick, Guy Caljon, Eric Muraille, Ian R. Humphreys, Louis Boon, Jo A. Van Ginderachter, Stefan Magez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In many infectious diseases, the immune response operates as a double-edged sword. While required for protective immunity, infection-induced inflammation can be detrimental if it is not properly controlled, causing collateral body damage and potentia
Externí odkaz:
https://doaj.org/article/2c88432ad857445596159ccb25ccec62
Autor:
Chloé Michaudel, Florent Bataille, Isabelle Maillet, Louis Fauconnier, Cyril Colas, Harry Sokol, Marjolène Straube, Aurélie Couturier-Maillard, Laure Dumoutier, Jacques van Snick, Valérie F. Quesniaux, Dieudonnée Togbe, Bernhard Ryffel
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Airborne ozone exposure causes severe lung injury and inflammation. The aryl hydrocarbon Receptor (AhR) (1), activated in pollutant-induced inflammation, is critical for cytokine production, especially IL-22 and IL-17A. The role of AhR in ozone-induc
Externí odkaz:
https://doaj.org/article/50adb8baaf7f4721927e5fc3536627e5
Autor:
Danielle Freches, Natacha Rocks, Harshad P. Patil, Fabienne Perin, Jacques Van Snick, Rita Vanbever, Didier Cataldo
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
PEGylation is a promising approach to increase the residence time of antibody fragments in the lungs and sustain their therapeutic effects. However, concerns arise as to the potential pulmonary toxicity of antibody fragments conjugated to high molecu
Externí odkaz:
https://doaj.org/article/371a5f14a0c8448c99c1d9cb15354492