Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Jacques, Galipeau"'
Autor:
Andrea Pennati, Jacques Galipeau, Zachary Morris, Christian Capitini, Mahfuzur Rahman, Zafer Gurel, Randall Kimple
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0665a5fe90e94b39823187d4db0ec134
Autor:
Rahul Das, Jayeeta Giri, Pradyut K. Paul, Nicole Froelich, Raghavan Chinnadurai, Sara McCoy, Wade Bushman, Jacques Galipeau
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Adipogenic differentiation of visceral adipose tissue-resident multipotent mesenchymal stromal cells (VA-MSC) into adipocytes is metabolically protective. Under chronic inflammatory stress, this neoadipogenesis process is suppressed by vario
Externí odkaz:
https://doaj.org/article/94ed8962d64847708cc2df08326912ee
Autor:
Elizabeth Stenger, Cynthia R. Giver, Amelia Langston, Daniel Kota, Pankoj Kumar Das, Raghavan Chinnadurai, Jacques Galipeau, Edmund K. Waller, Muna Qayed
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the curative potential of hematopoietic cell transplantation (HCT) for hematologic malignancies, graft-versus-host disease (GVHD) remains a substantial cause of morbidity and mortality, particularly if treatment is refractory. Treatment with
Externí odkaz:
https://doaj.org/article/5a3104e1dc0b44048981f61e6756013a
Autor:
Raghavan Chinnadurai, Paul D. Bates, Keith A. Kunugi, Kwangok P. Nickel, Larry A. DeWerd, Christian M. Capitini, Jacques Galipeau, Randall J. Kimple
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mesenchymal stromal cells (MSCs) are being tested as a cell therapy in clinical trials for dozens of inflammatory disorders, with varying levels of efficacy reported. Suitable and robust preclinical animal models for testing the safety and efficacy o
Externí odkaz:
https://doaj.org/article/9f6a95f5cd4c45778cceb90c01c5c952
Autor:
Doan C. Nguyen, Swetha Garimalla, Haopeng Xiao, Shuya Kyu, Igor Albizua, Jacques Galipeau, Kuang-Yueh Chiang, Edmund K. Waller, Ronghu Wu, Greg Gibson, James Roberson, Frances E. Lund, Troy D. Randall, Iñaki Sanz, F. Eun-Hyung Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Antibody-secreting cells (ASC) such as plasma cells must migrate to the bone marrow to survive, but microniche elements that promote survival are unknown. Here the authors define specific factors from the microniche that can maintain ASC in vitro for
Externí odkaz:
https://doaj.org/article/8d6c5b762cbe4e5192797c6d2043c3fe
Autor:
Jacques Galipeau
Publikováno v:
Cell and Gene Therapy Insights. :11-17
Autor:
Pradyut K. Paul, Rahul Das, Travis Drow, Emily A. Nylen, Arnaldo Henrique de Souza, Zunyi Wang, Michael W. Wood, Dawn B. Davis, Dale E. Bjorling, Jacques Galipeau
Publikováno v:
American Journal of Transplantation. 22:2571-2585
Allogeneic islet transplantation is a promising experimental therapy for poorly controlled diabetes. Despite pharmacological immunosuppression, long-term islet engraftment remains elusive. Here, we designed a synthetic fusion transgene coupling PD-L1
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1923-1934.e4 (2020)
Summary: Mesenchymal stromal cell (MSC)-based therapy for inflammatory diseases involves paracrine and efferocytotic activation of immunosuppressive interleukin-10+ (IL-10+) macrophages. The paracrine pathway for MSC-mediated IL-10+ macrophage functi
Externí odkaz:
https://doaj.org/article/7109fd52e22f46a4a437056c3d21919c
Autor:
Maria C. Naskou, Scarlett M. Sumner, Anna Chocallo, Hannah Kemelmakher, Merrilee Thoresen, Ian Copland, Jacques Galipeau, John F. Peroni
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2018)
Abstract Background Mesenchymal stem cells (MSCs) produced for clinical purposes rely on culture media containing fetal bovine serum (FBS) which is xenogeneic and has the potential to significantly alter the MSC phenotype, rendering these cells immun
Externí odkaz:
https://doaj.org/article/fcd5f8f9b255476282d9b9951053f2d2
Autor:
Raghavan Chinnadurai, Devi Rajan, Muna Qayed, Dalia Arafat, Marco Garcia, Yifei Liu, Subra Kugathasan, Larry J. Anderson, Greg Gibson, Jacques Galipeau
Publikováno v:
Cell Reports, Vol 22, Iss 9, Pp 2504-2517 (2018)
Summary: Assays that can characterize MSC immune potency need to be identified for use in advanced clinical trials. MSCs possess a number of putative regenerative and immunomodulatory properties, and an assay matrix approach may best capture involved
Externí odkaz:
https://doaj.org/article/44266d5a3f354f9e8b875cd62ba51295