Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Jacques, Descotes"'
Autor:
Peter Vestbjerg, Claire Friry-Santini, Philippe Ancian, Hollie Skaggs, Jacques Descotes, Antonio Iglesias, Henrik Duelund Pedersen, Tina Rubic-Schneider, Linda Allais
Publikováno v:
Regulatory Toxicology and Pharmacology. 94:271-275
There is a growing need to consider non-rodent species for the immunological safety evaluation of drug candidates. The EU Framework-6 RETHINK Project demonstrated that the Gottingen Minipig is a relevant animal model for regulatory toxicology studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5ddbc677f49ecce5d3cc93bf909159
https://doi.org/10.1016/j.yrtph.2018.02.015
https://doi.org/10.1016/j.yrtph.2018.02.015
Autor:
Adolfo López-Noriega, Anne-Pascale Trichet, Jacques Descotes, Charlotte Peloso, Christophe Roberge, Joël Richard
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9250, p 9250 (2021)
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9250, p 9250 (2021)
Volume 22
Issue 17
The present study aims to investigate the loco-regional tolerability and injection parameters (i.e., flow rate and administration volume) of an in situ forming depot (ISFD) in Göttingen minipigs, to secure both the therapeutic procedure and complian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ffcf159a6efb742f0f1dce49851a36
https://doi.org/10.3390/ijms22179250
https://doi.org/10.3390/ijms22179250
Autor:
Jacques Descotes, Thierry Vial
Publikováno v:
Biotechnology and Safety Assessment ISBN: 9780367811662
Biotechnology and Safety Assessment
Biotechnology and Safety Assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b586b776b63f0b09f3d862b040cadb6
https://doi.org/10.1201/9780367811662-13
https://doi.org/10.1201/9780367811662-13
Autor:
Jacques Descotes
Publikováno v:
Nijkamp and Parnham's Principles of Immunopharmacology ISBN: 9783030108090
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f508129cfe58a019f27fbd35b04951e2
https://doi.org/10.1007/978-3-030-10811-3_11
https://doi.org/10.1007/978-3-030-10811-3_11
Autor:
M. Bourtourault, Roy Forster, Y.J. Chung, G. Sire, C. Puel, Jacques Descotes, Takashi Mikogami, J. Silvano, François Spézia
Publikováno v:
Regulatory Toxicology and Pharmacology. 69:398-407
TM0601p is a whey protein isolate derived from cow milk, containing a concentrated amount of transforming growth factor β2 (TGF-β2), and is intended for nutritional use in infants and adults. In vivo and in vitro studies have been performed to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c73f966e709fdbaf9a251130000b13
https://doi.org/10.1016/j.yrtph.2014.05.003
https://doi.org/10.1016/j.yrtph.2014.05.003
Autor:
Thierry Cueto, Michel Boudinaud, Jean-Michel Gaulier, Jacques Descotes, Julie Maublanc, S. Dulaurent, Gilles Delhome, Gérard Lachâtre, Alexandra Boucher, Laurent Imbert
Publikováno v:
Journal of Analytical Toxicology. 38:410-415
Methoxetamine (MXE) is increasingly used and abused, as it is frequently presented as being safer than ketamine, and legal. Cases of only MXE consumption being associated with the occurrence of seizures are rarely reported. A single MXE intoxication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8b1d0510b5566d32b7767636f4c4e4
https://doi.org/10.1093/jat/bku052
https://doi.org/10.1093/jat/bku052
Publikováno v:
Toxicology Letters. 295:S86-S87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2a9500f42502e7a2beeb51829d69989
https://doi.org/10.1016/j.toxlet.2018.06.566
https://doi.org/10.1016/j.toxlet.2018.06.566
Autor:
Aurore Gouraud, Amélie Daveluy, Aurélie Grandvuillemin, Jacques Descotes, Thierry Vial, Pascal Auriche, C. Bourne
Publikováno v:
British Journal of Clinical Pharmacology. 75:1063-1067
Aims The risk of hypoglycaemia with tramadol (TRM) is not well described. Our aim was to analyze spontaneous reports of hypoglycaemia registered in the French Pharmacovigilance database and to compare these data with two other step-2 analgesic drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d37563d8211c3801872299b299763e8
https://doi.org/10.1111/j.1365-2125.2012.04451.x
https://doi.org/10.1111/j.1365-2125.2012.04451.x
Autor:
Quadiri Timour, L. Lerond, Jacques Descotes, Leila Dehina, A. Tabib, V. Blanc-Guillemaud, Ph. Chevalier, N. Dizerens, Fanny Vaillant, Bernard Bui-Xuan, C. Bui-Xuan
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 386:205-215
Myocardial ischemia affects mitochondrial function leading to ionic imbalance and susceptibility to ventricular fibrillation. Trimetazidine (TMZ), a metabolic agent, is clinically used as an anti-anginal therapy. This study was conducted to compare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018f048ec69079a73a322aeb014ffac7
https://doi.org/10.1007/s00210-012-0826-z
https://doi.org/10.1007/s00210-012-0826-z
Autor:
Fanny Vaillant, Zahida Mamou, Bernard Bui-Xuan, Quadiri Timour, Guy Chazot, Leila Dehina, A. Tabib, Muriel Bost, Jacques Descotes, Lamia Hamdan
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 26:170-173
The involvement of psychotropic drugs in sudden deaths has been highlighted. The objective of this work was to establish a link between selenium levels in heart tissue, psychotropic treatment and sudden death. Selenium levels were measured by electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcffa1cad2321614afaac508d6d89941
https://doi.org/10.1016/j.jtemb.2012.04.025
https://doi.org/10.1016/j.jtemb.2012.04.025