Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Jacques, Couet"'
Autor:
Audrey Morin-Grandmont, Elisabeth Walsh-Wilkinson, Sara-Ève Thibodeau, Dominique K. Boudreau, Marie Arsenault, Yohan Bossé, Jacques Couet
Publikováno v:
PeerJ, Vol 12, p e17434 (2024)
We propose a new mouse (C57Bl6/J) model combining several features of heart failure with preserved ejection fraction encountered in older women, including hypertension from Angiotensin II infusion (AngII), menopause, and advanced age. To mimic menopa
Externí odkaz:
https://doaj.org/article/bcd2daa9a3004cbea005320bdb80c6a6
Autor:
Sara-Ève Thibodeau, Emylie-Ann Labbé, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Marie Arsenault, Jacques Couet
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 892 (2024)
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome characterised by multiple risk factors touching various organs outside the heart. Using a murine HFpEF model, we studied cardiac reverse remodelling (RR) after stoppin
Externí odkaz:
https://doaj.org/article/507a1bbaea064cf281455bea9e689418
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Aortic valve regurgitation (AR) results in left ventricle (LV) volume overload (VO) leading to its dilation and hypertrophy (H). We study a rat model of severe AR induced by puncturing one or two leaflets using a catheter. Most of
Externí odkaz:
https://doaj.org/article/961e466ed4924207aebdd1967a0a59dd
Publikováno v:
PeerJ, Vol 9, p e11085 (2021)
We studied by conventional and speckle-tracking echocardiography, the response of the left ventricle (LV) to a three-week continuous infusion of isoproterenol (Iso), a non-specific beta-adrenergic receptor agonist in male and female C57Bl6/J mice. Be
Externí odkaz:
https://doaj.org/article/fa5e448006e948ffab80cf690593367c
Publikováno v:
FEBS Open Bio, Vol 8, Iss 10, Pp 1624-1635 (2018)
Cardiac hypertrophy (CH) is an important and independent predictor of morbidity and mortality. Through expression profiling, we recently identified a subset of genes (Dhrs7c, Decr, Dhrs11, Dhrs4, Hsd11b1, Hsd17b10, Hsd17b8, Blvrb, Pecr), all of which
Externí odkaz:
https://doaj.org/article/aebf7bb00875482eab8659b90eb472ee
Autor:
Élisabeth Walsh-Wilkinson, Mohamed Lamine Aidara, Audrey Morin-Grandmont, Sara-Ève Thibodeau, Juliette Gagnon, Mathieu Genest, Marie Arsenault, Jacques Couet
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H643-H658
Age, hypertension, and the female sex are among the risk factors in the development of heart failure with preserved ejection fraction. We studied by standard and speckle-tracking echocardiography (STE), the response of the left ventricle (LV) to agin
Autor:
Catherine Beaumont, Élisabeth Walsh-Wilkinson, Marie-Claude Drolet, Élise Roussel, Marie Arsenault, Jacques Couet
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Aortic valve regurgitation (AR) imposes a volume overload (VO) to the left ventricle (LV). Male rats with a pathological heart overload usually progress more quickly towards heart failure than females. We examined whether a sexual dimorphism
Externí odkaz:
https://doaj.org/article/19273e3852134af8ad0171b0556572c3
Autor:
Elisabeth Walsh-Wilkinson, Catherine Beaumont, Marie-Claude Drolet, Ève-Marie Roy, Charlie Le Houillier, Jonathan Beaudoin, Marie Arsenault, Jacques Couet
Publikováno v:
PeerJ, Vol 7, p e7924 (2019)
Aortic valve regurgitation (AR) can result in heart failure from chronic overloading of the left ventricle (LV). Little is known of the role of estrogens in the LV responses to this condition. The aim of the study was to compare LV remodeling in fema
Externí odkaz:
https://doaj.org/article/4c030f88184947d3bbc638faa6abbba8
Autor:
Élisabeth Walsh-Wilkinson, Marie-Claude Drolet, Charlie Le Houillier, Ève-Marie Roy, Marie Arsenault, Jacques Couet
Publikováno v:
PeerJ, Vol 7, p e7461 (2019)
Background. Men and women differ in their susceptibility to cardiovascular disease, though the underlying mechanism has remained elusive. Heart disease symptoms, evolution and response to treatment are often sex-specific. This has been studied in ani
Externí odkaz:
https://doaj.org/article/4da74235677b444b818537e4f033a769
Autor:
Ons Marsit, Marie-Annick Clavel, Amélie Paquin, Valérie Deschênes, Sandra Hadjadj, Isabelle Sénéchal-Dumais, Jacques Couet, Marie Arsenault, Mark D. Handschumacher, Robert A. Levine, Elena Aikawa, Philippe Pibarot, Jonathan Beaudoin
Publikováno v:
Journal of the American College of Cardiology. 80(5)
Ischemic mitral regurgitation (MR) is primarily caused by left ventricle deformation, but leaflet thickening with fibrotic changes are also observed in the valve. Increased levels of 5-hydroxytryptamine (5-HT; ie, serotonin) are described after myoca