Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Jacques, Colinge"'
Autor:
Sarah Figarol, Célia Delahaye, Rémi Gence, Aurélia Doussine, Juan Pablo Cerapio, Mathylda Brachais, Claudine Tardy, Nicolas Béry, Raghda Asslan, Jacques Colinge, Jean-Philippe Villemin, Antonio Maraver, Irene Ferrer, Luis Paz-Ares, Linda Kessler, Francis Burrows, Isabelle Lajoie-Mazenc, Vincent Dongay, Clara Morin, Amélie Florent, Sandra Pagano, Estelle Taranchon-Clermont, Anne Casanova, Anne Pradines, Julien Mazieres, Gilles Favre, Olivier Calvayrac
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Drug-tolerance has emerged as one of the major non-genetic adaptive processes driving resistance to targeted therapy (TT) in non-small cell lung cancer (NSCLC). However, the kinetics and sequence of molecular events governing this adaptive r
Externí odkaz:
https://doaj.org/article/5612bcd3b3224ee3a0571c7b20e6c3df
Autor:
Lena M. Sauer, Rodrigo Canovas, Daniel Roche, Hosam Shams-Eldin, Patrice Ravel, Jacques Colinge, Ralph T. Schwarz, Choukri Ben Mamoun, Eric Rivals, Emmanuel Cornillot
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-19 (2023)
Abstract Background Protozoan parasites are known to attach specific and diverse group of proteins to their plasma membrane via a GPI anchor. In malaria parasites, GPI-anchored proteins (GPI-APs) have been shown to play an important role in host–pa
Externí odkaz:
https://doaj.org/article/bbb75fbdd038457eb6a28f2abb56c317
Autor:
Evelyne Lopez-Crapez, Luca Costa, Guillaume Tosato, Jeanne Ramos, Thibault Mazard, Janique Guiramand, Alain Thierry, Jacques Colinge, Pierre-Emmanuel Milhiet, Christine Bénistant
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Besides the standard parameters used for colorectal cancer (CRC) management, new features are needed in clinical practice to improve progression-free and overall survival. In some cancers, the microenvironment mechanical properties can contr
Externí odkaz:
https://doaj.org/article/b8dea8acb05240069e9e7ddb5155b135
Autor:
Emilia Rabia, Véronique Garambois, Christine Dhommée, Christel Larbouret, Laurie Lajoie, Yoan Buscail, Gabriel Jimenez-Dominguez, Sylvie Choblet-Thery, Emmanuelle Liaudet-Coopman, Martine Cerutti, Marta Jarlier, Patrice Ravel, Laurent Gros, Nelly Pirot, Gilles Thibault, Eugene A. Zhukovsky, Pierre-Emmanuel Gérard, André Pèlegrin, Jacques Colinge, Thierry Chardès
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The ErbB family of receptor tyrosine kinases is a primary target for small molecules and antibodies for pancreatic cancer treatment. Nonetheless, the current treatments for this tumor are not optimal due to lack of efficacy, resistance, or toxicity.
Externí odkaz:
https://doaj.org/article/8a10b603d78a414f85898e71f788257b
Autor:
Diala Kantar, Emilie Bousquet Mur, Maicol Mancini, Vera Slaninova, Yezza Ben Salah, Luca Costa, Elodie Forest, Patrice Lassus, Charles Géminard, Florence Boissière-Michot, Béatrice Orsetti, Charles Theillet, Jacques Colinge, Christine Benistant, Antonio Maraver, Lisa Heron-Milhavet, Alexandre Djiane
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Alterations to cell polarization or to intercellular junctions are often associated with epithelial cancer progression, including breast cancers (BCa). We show here that the loss of the junctional scaffold protein MAGI1 is associated with ba
Externí odkaz:
https://doaj.org/article/360a50e2dc1748519708e862bd828014
Autor:
Gabriel Jimenez-Dominguez, Patrice Ravel, Stéphan Jalaguier, Vincent Cavaillès, Jacques Colinge
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Modular response analysis (MRA) is a widely used inference technique developed to uncover directions and strengths of connections in molecular networks under a steady-state condition by means of perturbation experiments. We devised several e
Externí odkaz:
https://doaj.org/article/d94098b1f0d3446eb30d3bf3eb359a2a
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4, p e1009312 (2022)
The development of high-throughput genomic technologies associated with recent genetic perturbation techniques such as short hairpin RNA (shRNA), gene trapping, or gene editing (CRISPR/Cas9) has made it possible to obtain large perturbation data sets
Externí odkaz:
https://doaj.org/article/039642338f284a4f883cb8fe6cb83a0b
Autor:
Rita Tanos, Guillaume Tosato, Amaelle Otandault, Zahra Al Amir Dache, Laurence Pique Lasorsa, Geoffroy Tousch, Safia El Messaoudi, Romain Meddeb, Mona Diab Assaf, Marc Ychou, Stanislas Du Manoir, Denis Pezet, Johan Gagnière, Pierre‐Emmanuel Colombo, William Jacot, Eric Assénat, Marie Dupuy, Antoine Adenis, Thibault Mazard, Caroline Mollevi, José María Sayagués, Jacques Colinge, Alain R. Thierry
Publikováno v:
Advanced Science, Vol 7, Iss 18, Pp n/a-n/a (2020)
Abstract While the utility of circulating cell‐free DNA (cfDNA) in cancer screening and early detection have recently been investigated by testing genetic and epigenetic alterations, here, an original approach by examining cfDNA quantitative and st
Externí odkaz:
https://doaj.org/article/4c77fbdb6edd4d97afd2a71f314fcdd5
Autor:
Ankit Dwivedi, Christelle Reynes, Axel Kuehn, Daniel B. Roche, Nimol Khim, Maxim Hebrard, Sylvain Milanesi, Eric Rivals, Roger Frutos, Didier Menard, Choukri Ben Mamoun, Jacques Colinge, Emmanuel Cornillot
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-17 (2017)
Abstract Background Plasmodium falciparum malaria is one of the most widespread parasitic infections in humans and remains a leading global health concern. Malaria elimination efforts are threatened by the emergence and spread of resistance to artemi
Externí odkaz:
https://doaj.org/article/e53ac2f55d0b481c96652eb282159804
Autor:
Jean-Philippe Villemin, Laia Bassaganyas, Didier Pourquier, Florence Boissière, Simon Cabello-Aguilar, Evelyne Crapez, Rita Tanos, Emmanuel Cornillot, Andrei Turtoi, Jacques Colinge
Publikováno v:
Nucleic Acids Research.
The study of cellular networks mediated by ligand-receptor interactions has attracted much attention recently owing to single-cell omics. However, rich collections of bulk data accompanied with clinical information exists and continue to be generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f738a92d1eb6af0c1a12e35920e46d
https://doi.org/10.1093/nar/gkad352
https://doi.org/10.1093/nar/gkad352