Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jacquelynn Morrissey"'
Autor:
Fernanda C. P. Mesquita, Eliel S. Leite, Jacquelynn Morrissey, Catarina Freitas, Tatiana Coelho-Sampaio, Camila Hochman-Mendez
Publikováno v:
Cells, Vol 11, Iss 24, p 3955 (2022)
Laminins (LNs) play a central role in the self-assembly and maintenance of basement membranes and are involved in critical interactions between cells and other extracellular matrix (ECM) proteins. Among the defined, xeno-free ECM culture matrices, LN
Externí odkaz:
https://doaj.org/article/bc76d0158a8e44e98ba31487039daf62
Publikováno v:
Cells, Vol 11, Iss 13, p 2092 (2022)
Close examination of the initial results of cardiovascular cell therapy clinical trials indicates the importance of patient-specific differences on outcomes and the need to optimize or customize cell therapies. The fields of regenerative medicine and
Externí odkaz:
https://doaj.org/article/17fd08dc1b67456dbe5359ea2f5b9b74
Autor:
Fernanda C. Paccola Mesquita, Camila Hochman-Mendez, Jacquelynn Morrissey, Luiz C. Sampaio, Doris A. Taylor
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The number of high-quality cells required for engineering an adult human-sized bioartificial organ is greater than one billion. Until the emergence of induced pluripotent stem cells (iPSCs), autologous cell sources of this magnitude and with the requ
Externí odkaz:
https://doaj.org/article/380c7bbdd814424a8924a44be38fd078
Autor:
Camila Hochman-Mendez, Fernanda C.P. Mesquita, Jacquelynn Morrissey, Ernesto Curty da Costa, Jorn Hulsmann, Karis Tang-Quan, Yutao Xi, Po-Feng Lee, Luiz C. Sampaio, Doris A. Taylor
Publikováno v:
Acta Biomaterialia. 141:48-58
The heart is a highly complex, multicellular solid organ with energy-demanding processes that require a dense vascular network, extensive cell-cell interactions, and extracellular matrix (ECM)-mediated crosstalk among heterogeneous cell populations.
Autor:
Fernanda C.P. Mesquita, Jacquelynn Morrissey, Gustavo Monnerat, Gilberto B. Domont, Fabio C. S. Nogueira, Camila Hochman-Mendez
Publikováno v:
Cells Tissues Organs. 212:32-44
During fetal development, cardiomyocytes switch from glycolysis to oxidative metabolism to sustain the energy requirements of functional cells. State-of-the-art cardiac differentiation protocols yield phenotypically immature cardiomyocytes, and commo
Autor:
Jacquelynn Morrissey, Gilberto B. Domont, Po-Feng Lee, Fábio C. S. Nogueira, Camila Hochman-Mendez, Yutao Xi, Doris A. Taylor, Fernanda C.P. Mesquita, Luiz C. Sampaio, Helen Andersson, Gustavo Monnerat
Publikováno v:
Biomaterials Science. 9:3737-3749
New robust and reproducible differentiation approaches are needed to generate induced pluripotent stem cell (iPSC)-derived cardiomyocytes of specific subtypes in predictable quantities for tissue-specific disease modeling, tissue engineering, and eve
Autor:
Hassan Virk, Fernanda C.P. Mesquita, Katrina Rhett, Osman E. Rodriguez, Stefan M. Kren, Lourdes Chacon-Alberty, Jacquelynn Morrissey, Camila Hochman-Mendez, Doris A. Taylor, Matthew J. Robertson, Ernesto C da Costa, Luiz C. Sampaio
Publikováno v:
Physiological Reports
To expand the application of perfusion decellularization beyond isolated single organs, we used the native vasculature of adult and neonatal rats to systemically decellularize the organs of a whole animal in situ. Acellular scaffolds were generated f
Autor:
Gustavo Monnerat, Yutao Xi, Fernanda C.P. Mesquita, Doris A. Taylor, Luiz C. Sampaio, Camila Hochman-Mendez, Jacquelynn Morrissey, Fábio C. S. Nogueira, Gilberto B. Domont
Publikováno v:
Circulation Research. 127
Extracellular matrix (ECM) can directly modulate cell proliferation, migration and differentiation by mediating diverse growth factors and signaling interactions. Protocols for cardiomyocyte differentiation of induced pluripotent stem cells (iPSCs) t
Publikováno v:
Cells, tissues, organs. 211(4)
Bioengineering a solid organ for organ replacement is a growing endeavor in regenerative medicine. Our approach – recellularization of a decellularized cadaveric organ scaffold with human cells – is currently the most promising approach to buildi
Autor:
Jacquelynn Morrissey, Luiz C. Sampaio, Fernanda C.P. Mesquita, Doris A. Taylor, Camila Hochman-Mendez
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2019 (2019)
Stem Cells International, Vol 2019 (2019)
The number of high-quality cells required for engineering an adult human-sized bioartificial organ is greater than one billion. Until the emergence of induced pluripotent stem cells (iPSCs), autologous cell sources of this magnitude and with the requ