Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jacquelyne Ka-Li Sun"'
Publikováno v:
PLoS Biology, Vol 22, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/aa56fe3b578143869368d55a4c1dd350
Autor:
Shaohong Isaac Peng, Lok I. Leong, Jacquelyne Ka-Li Sun, Zhefan Stephen Chen, Hei-Man Chow, Ho Yin Edwin Chan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 102-115 (2022)
Polyglutamine (polyQ) diseases, including spinocerebellar ataxias and Huntington’s disease, are progressive neurodegenerative disorders caused by CAG triplet-repeat expansion in the coding regions of disease-associated genes. In this study, we foun
Externí odkaz:
https://doaj.org/article/742fe03b25504f89bb4861cfdbe55b3d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Although immune checkpoint inhibitors (ICIs) have been shown to yield promising therapeutic outcomes in a small subset of patients with triple negative breast cancer (TNBC), the majority of patients either do not respond or subsequently de
Externí odkaz:
https://doaj.org/article/5dc74c03c0024904801f2397e4b72253
Autor:
Hei‐Man Chow, Jacquelyne Ka‐Li Sun, Ronald P. Hart, Kenneth King‐Yip Cheng, Clara H. L. Hung, Tsun‐Ming Lau, Kin‐Ming Kwan
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract Early changes in astrocyte energy metabolism are associated with late‐onset Alzheimer's disease (LOAD), but the underlying mechanism remains elusive. A previous study suggested an association between a synonymous SNP (rs1012672, C→T) in
Externí odkaz:
https://doaj.org/article/20179694e8944d0e88c9468969d8d620
Autor:
Jacquelyne Ka‐Li Sun, Deng Wu, Genper Chi‐Ngai Wong, Tsun‐Ming Lau, Meigui Yang, Ronald P. Hart, Kin‐Ming Kwan, Ho Yin Edwin Chan, Hei‐Man Chow
Publikováno v:
Aging Cell. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d54f8209e07910949569f6e45e7f6cfa
https://doi.org/10.1111/acel.13772
https://doi.org/10.1111/acel.13772
Autor:
Dennis Dik‐Long Chau, Wen Li, Wai Wa Ray Chan, Jacquelyne Ka‐Li Sun, Yuqi Zhai, Hei‐Man Chow, Kwok‐Fai Lau
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(11)
Neurite outgrowth is a fundamental process in neurons that produces extensions and, consequently, neural connectivity. Neurite damage and atrophy are observed in various brain injuries and disorders. Understanding the intrinsic pathways of neurite ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c71711b0846ae9be0ddc81ef79e257
https://pubmed.ncbi.nlm.nih.gov/36250347
https://pubmed.ncbi.nlm.nih.gov/36250347
Autor:
Shaohong Isaac Peng, Lok I Leong, Jacquelyne Ka-Li Sun, Zhefan Stephen Chen, Hei-Man Chow, Ho Yin Edwin Chan
Publikováno v:
Molecular therapy. Nucleic acids. 29
Polyglutamine (polyQ) diseases, including spinocerebellar ataxias and Huntington's disease, are progressive neurodegenerative disorders caused by CAG triplet-repeat expansion in the coding regions of disease-associated genes. In this study, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e16abb2837fed5729f785a0fee4de1
https://pubmed.ncbi.nlm.nih.gov/35795484
https://pubmed.ncbi.nlm.nih.gov/35795484
Autor:
Kin Ming Kwan, Tsun Ming Lau, Ronald P. Hart, Kenneth K.Y. Cheng, Jacquelyne Ka Li Sun, Hei Man Chow, Clara Hiu-Ling Hung
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Early changes in astrocyte energy metabolism are associated with late‐onset Alzheimer's disease (LOAD), but the underlying mechanism remains elusive. A previous study suggested an association between a synonymous SNP (rs1012672, C→T) in LRP6 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38fc2084280cb7139917afe793a74d0
http://europepmc.org/articles/PMC8373092
http://europepmc.org/articles/PMC8373092
Autor:
Shaohong, Peng, Pei, Guo, Xiao, Lin, Ying, An, Kong Hung, Sze, Matthew Ho Yan, Lau, Zhefan Stephen, Chen, Qianwen, Wang, Wen, Li, Jacquelyne Ka-Li, Sun, Sum Yi, Ma, Ting-Fung, Chan, Kwok-Fai, Lau, Jacky Chi Ki, Ngo, Kin Ming, Kwan, Chun-Ho, Wong, Sik Lok, Lam, Steven C, Zimmerman, Tiziano, Tuccinardi, Zhong, Zuo, Ho Yu, Au-Yeung, Hei-Man, Chow, Ho Yin Edwin, Chan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Small CAG (sCAG) RNAs are neurotoxic, but their role in polyglutamine degeneration remains to be fully elucidated. We observed that cellular expression of sCAGs is sufficient to induce neuronal DNA damage and discovered that the transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8193a0f0761e454f30386298ac074cb8
https://pubmed.ncbi.nlm.nih.gov/33947817
https://pubmed.ncbi.nlm.nih.gov/33947817
Autor:
Wu, Deng1 (AUTHOR), Sun, Jacquelyne Ka-Li1 (AUTHOR), Chow, Kim Hei-Man1,2,3 (AUTHOR) heimanchow@cuhk.edu.hk
Publikováno v:
PLoS Biology. 4/23/2024, Vol. 22 Issue 4, p1-34. 34p.