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pro vyhledávání: '"Jacquelyn T. Wright"'
Autor:
Roisin E. O’Brien, Jack P.K. Bravo, Delisa Ramos, Grace N. Hibshman, Jacquelyn T. Wright, David W. Taylor
Cascades are RNA-guided multi-subunit CRISPR-Cas surveillances complexes that target foreign nucleic acids for destruction. Here, we present a 2.9-Å resolution cryo-electron (cryo-EM) structure of the D. vulgaris type I-C Cascade bound to a double-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16abd116161089dd5f7ab7a78667c045
https://doi.org/10.1101/2022.06.15.496202
https://doi.org/10.1101/2022.06.15.496202
Autor:
Roisin E. O’Brien, Jack P.K. Bravo, Delisa Ramos, Grace N. Hibshman, Jacquelyn T. Wright, David W. Taylor
Publikováno v:
Mol Cell
Type I CRISPR-Cas systems employ multi-subunit Cascade effector complexes to target foreign nucleic acids for destruction. Here, we present structures of D. vulgaris type I-C Cascade at various stages of double-stranded (ds)DNA target capture, reveal