Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jacquelyn T Saunders"'
Autor:
Brent Holmes, Angelica Benavides-Serrato, Jacquelyn T. Saunders, Sunil Kumar, Robert N. Nishimura, Joseph Gera
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 951-965 (2021)
The Hippo and mTOR signaling cascades are major regulators of cell growth and division. Aberrant regulation of these pathways has been demonstrated to contribute to gliomagenesis and result in enhanced glioblastoma proliferation and invasive characte
Externí odkaz:
https://doaj.org/article/b01e8986ccf741549a1fff9a968ce1fb
Autor:
Jacquelyn T. Saunders, Sunil Kumar, Angelica Benavides-Serrato, Brent Holmes, Kennedy E. Benavides, Muhammad T. Bashir, Robert N. Nishimura, Joseph Gera
Publikováno v:
Journal of Neuro-Oncology. 163:207-218
Introduction HGF/c-MET signaling is a significant driver of glioblastoma (GBM) growth and disease progression. Unfortunately, c-MET targeted therapies have been found to be largely ineffective suggesting additional redundant mechanisms of c-MET activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af1f1b527e20811fcb6f4bcd6e455df
https://doi.org/10.1007/s11060-023-04331-5
https://doi.org/10.1007/s11060-023-04331-5
Autor:
Chris Hino, Grace Chan, Gwen Jordaan, Sophia S. Chang, Jacquelyn T. Saunders, Mohammad T. Bashir, James E. Hansen, Joseph Gera, Richard H. Weisbart, Robert N. Nishimura
Publikováno v:
Cell Stress and Chaperones.
Heat shock proteins (HSPs), especially Hsp70 (HSPA1), have been associated with cellular protection from various cellular stresses including heat, hypoxia-ischemia, neurodegeneration, toxins, and trauma. Endogenous HSPs are often synthesized in direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5088e42a4fd95c0d30dfd168cdfab94
https://doi.org/10.1007/s12192-023-01349-6
https://doi.org/10.1007/s12192-023-01349-6
Autor:
Chris Hino, Grace Chan, Gwen Jordaan, Sophia S Chang, Jacquelyn T Saunders, Mohammad T Bashir, James E Hansen, Joseph Gera, Richard H Weisbart, Robert N Nishimura
Heat shock proteins (HSPs), especially Hsp70 (HSPA1), have been associated with cellular protection from various cellular stresses including heat, hypoxia-ischemia, neurodegeneration, toxins, and trauma. Endogenous HSPs are often synthesized in direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a5f5c4abf1e10850f4f5e179a746a8
https://doi.org/10.1101/2023.02.22.529417
https://doi.org/10.1101/2023.02.22.529417
Autor:
Sunil Kumar, Robert N. Nishimura, Jacquelyn T Saunders, Angelica Benavides-Serrato, Brent Holmes, Joseph Gera
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 951-965 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The Hippo and mTOR signaling cascades are major regulators of cell growth and division. Aberrant regulation of these pathways has been demonstrated to contribute to gliomagenesis and result in enhanced glioblastoma proliferation and invasive characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93125b3b9c909d064550cda15a19ad9f
https://doi.org/10.1016/j.neo.2021.07.005
https://doi.org/10.1016/j.neo.2021.07.005
Autor:
Angelica Benavides-Serrato, Jacquelyn T. Saunders, Sunil Kumar, Brent Holmes, Kennedy E. Benavides, Muhammad T. Bashir, Robert N. Nishimura, Joseph Gera
Publikováno v:
Cancer Letters. 562:216178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db70e0ae294e800283f2b8fe19eb2237
https://doi.org/10.1016/j.canlet.2023.216178
https://doi.org/10.1016/j.canlet.2023.216178
Autor:
Sunil Kumar, Jacquelyn T Saunders, Angelica Benavides-Serrato, Brent Holmes, Joseph Gera, Robert N. Nishimura
Publikováno v:
J Neurooncol
INTRODUCTION: Recent studies have suggested that dysregulated Hippo pathway signaling may contribute to glioblastoma proliferation and invasive characteristics. The downstream effector of the pathway, the Yes-associated protein (YAP) oncoprotein, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc6760bfbaf4c5571c9977c3531abf2
https://doi.org/10.1007/s11060-021-03699-6
https://doi.org/10.1007/s11060-021-03699-6
Autor:
Joseph Gera, Adam J Schreck, Angelica Benavides-Serrato, Kenna A. Landon, Brent Holmes, Jacquelyn T Saunders, Robert N. Nishimura
Publikováno v:
J Neurooncol
INTRODUCTION: Clinical trials directed at mechanistic target of rapamycin (mTOR) inhibition have yielded disappointing results in glioblastoma (GBM). A major mechanism of resistance involves the activation of a salvage pathway stimulating internal ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8169220e6a6ddb15c4dde224d2feea58
https://doi.org/10.1007/s11060-019-03274-0
https://doi.org/10.1007/s11060-019-03274-0
Autor:
Jacquelyn T Saunders, Alan Lichtenstein, Brent Holmes, Robert N. Nishimura, Angelica Benavides-Serrato, Joseph Gera
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 344 (2020)
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 344 (2020)
Internal ribosome entry site (IRES)-mediated protein synthesis has been demonstrated to play an important role in resistance to mechanistic target of rapamycin (mTOR) targeted therapies. Previously, we have demonstrated that the IRES trans-acting fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca042568c98ca76a9f1b40dfbc01751