Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jacquelyn Spathies"'
Autor:
Manoj Yadav, Prem Prashant Chaudhary, Brandon N D'Souza, Grace Ratley, Jacquelyn Spathies, Sundar Ganesan, Jordan Zeldin, Ian A Myles
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282569 (2023)
We recently used EPA databases to identify that isocyanates, most notably toluene diisocyanate (TDI), were the pollutant class with the strongest spatiotemporal and epidemiologic association with atopic dermatitis (AD). Our findings demonstrated that
Externí odkaz:
https://doaj.org/article/2b29079028a742ee997b921d32cf9e93
Publikováno v:
Metabolites, Vol 12, Iss 6, p 497 (2022)
MALDI imaging is a novel technique with which to study the pathophysiologies of diseases. Advancements in the field of metabolomics and lipidomics have been instrumental in mapping the signaling pathways involved in various diseases, such as cancer a
Externí odkaz:
https://doaj.org/article/8c22a03a49744f2bba2a046126c4cb2b
Autor:
Kenneth M. Adusei, Tran B. Ngo, Andrea L. Alfonso, Ravi Lokwani, Sabrina DeStefano, Maria Karkanitsa, Jacquelyn Spathies, Stephen M. Goldman, Christopher L. Dearth, Kaitlyn N. Sadtler
Publikováno v:
Cells Tissues Organs. 212:84-95
The rat model is an important resource in biomedical research due to its similarities to the human immune system and its use for functional studies. However, because of the preponderance of mouse models in foundational and mechanistic immunological s
Autor:
Jordan Zeldin, Prem Prashant Chaudhary, Jacquelyn Spathies, Manoj Yadav, Brandon N. D’Souza, Mohammadali E. Alishahedani, Portia Gough, Jobel Matriz, Andrew J. Ghio, Yue Li, Ashleigh A. Sun, Lawrence F. Eichenfield, Eric L. Simpson, Ian A. Myles
Publikováno v:
Science advances, vol 9, iss 1
Atopic dermatitis (AD) is a chronic inflammatory skin condition increasing in industrial nations at a pace that suggests environmental drivers. We hypothesize that the dysbiosis associated with AD may signal microbial adaptations to modern pollutants
Examining multi-level immune response to determine prevalence of COVID-19 in pediatric tonsillectomy
Autor:
Pamela Mudd, Nahir Romero, Hengameh Behzadpour, Qin Xu, Md Sohel Rana, Lyuba Gitman, Diego Preciado, Maria Karkanitsa, Jacquelyn Spathies, Kaitlyn Sadtler, Heather Kalish, Pamela L. Schwartzberg, Kalpana Manthiram
Publikováno v:
The Laryngoscope.
To determine the prevalence of COVID-19 in a cohort of children undergoing tonsillectomy through assessment of B cell immune responses to SARS-CoV-2 in both peripheral blood and tonsil tissue.In this cohort study at a tertiary pediatric hospital (Chi
Autor:
Kalpana Manthiram, Qin Xu, Pedro Milanez-Almeida, Andrew Martins, Andrea Radtke, Kenneth Hoehn, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney Stein, Sabrina Ramelli, Juraj Kabat, Hengameh Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick Duncker, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace Smith, Arthur Shaffer, Ian McBain, Stefania Pittaluga, Ronald Germain, Richard Apps, Kaitlyn Sadtler, Susan Moir, Daniel Chertow, Steven Kleinstein, Surender Khurana, John Tsang, Pamela Mudd, Pamela Schwartzberg
Publikováno v:
Research square.
SARS-CoV-2 infection triggers adaptive immune responses from both T and B cells. However, most studies focus on peripheral blood, which may not fully reflect immune responses in lymphoid tissues at the site of infection. To evaluate both local and sy
Autor:
Qin Xu, Pedro Milanez-Almeida, Andrew J. Martins, Andrea J. Radtke, Kenneth B. Hoehn, Cihan Oguz, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney Stein, Sabrina Ramelli, Juraj Kabat, Hengameh Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick C. Duncker, Moses M. Kitakule, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace Smith, Arthur Shaffer, Ian T. McBain, Peter J. McGuire, Stefania Pittaluga, Ronald N. Germain, Richard Apps, Daniella M. Schwartz, Kaitlyn Sadtler, Susan Moir, Daniel S. Chertow, Steven H. Kleinstein, Surender Khurana, John S. Tsang, Pamela Mudd, Pamela L. Schwartzberg, Kalpana Manthiram
Publikováno v:
Nature immunology. 24(1)
Most studies of adaptive immunity to SARS-CoV-2 infection focus on peripheral blood, which may not fully reflect immune responses at the site of infection. Using samples from 110 children undergoing tonsillectomy and adenoidectomy during the COVID-19
Autor:
Nicholas M. Mohr, Jenna R. Darrah, Carl I. Schulman, Whit Rooke, Kyle Pauly, Jeffrey T. Lai, Richard D. Blomberg, Rosemary A. Kozar, Maria Karkanitsa, Matthew D. Hall, Christopher A. Griggs, Marie Crandall, Kyle W. Cunningham, Jacquelyn Spathies, Heather Kalish, Kavita M. Babu, Mark J. Neavyn, Emily Ricotta, Kaitlyn Sadtler, Jameson Travers, Dominic Esposito, F. Dennis Thomas, Jennifer Mehalko, Jennifer M. Whitehill, Matthew Drew, Jon N Van Heukelom, Carleen Klumpp-Thomas, Kenneth M. Adusei, Lindsey A. Graham, Matthew J. Memoli, Jon D Dorfman, James C. Fell, Tran B. Ngo
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
In comparison to the general patient population, trauma patients show higher level detections of bloodborne infectious diseases, such as Hepatitis and Human Immunodeficiency Virus. In comparison to bloodborne pathogens, the prevalence of respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8486ad0ac90b32738d180ffaf21664
https://doi.org/10.1101/2021.08.10.21261849
https://doi.org/10.1101/2021.08.10.21261849
Autor:
Anandakumar Shunmugavel, Alison Han, Heather Kalish, William K. Gillette, Matthew D. Hall, Matthew Drew, Sam Michael, Kelly Snead, Jennifer L. Hicks, Barry I. Graubard, Susan Reed, Kyle Pauly, Carleen Klumpp-Thomas, Luz Angela Rosas, Holly Ann Baus, Jennifer A. Croker, Vanessa Wall, Olivia Belliveau, Michelle M. Kolberg, Jing Wang, Michael P. Fay, Kenneth M. Adusei, Rani Athota, Yan Li, Luca T. Giurgea, Lindsay Czajkowski, Nalyn Siripong, Jennifer Mehalko, Reid Simon, Tran B. Ngo, Eric W. Ford, Rachel Bean, Maria Karkanitsa, Steven E. Reis, Kaitlyn Sadtler, Andrew Kelly, Brittany Heffelfinger, Jameson Travers, Shannon Valenti, Adriana Cervantes-Medina, Peter Frank, Jacquelyn Spathies, Simon Messing, Ravi Lokwani, Sally Hunsberger, Cheryl Chairez, Monica Gouzoulis, Rocco Caldararo, John-Paul Denson, Dominic Esposito, Robert P. Kimberly, Matthew J. Memoli, Saifullah Shafiq
Publikováno v:
medRxiv
Asymptomatic SARS-CoV-2 infection and delayed implementation of diagnostics have led to poorly defined viral prevalence rates. To address this, we analyzed seropositivity in US adults who have not previously been diagnosed with COVID-19. Individuals
Autor:
Shannon Valenti, Luz Angela Rosas, Nalyn Siripong, Lindsay Czajkowski, Olivia Belliveau, Kyle Pauly, Carleen Klumpp-Thomas, Kenneth M. Adusei, Saifullah Shafiq, Jing Wang, Jameson Travers, Ravi Lokwani, Matthew Drew, Maria Karkanitsa, Reid Simon, Vanessa Wall, Yan Li, Steven E. Reis, Luca T. Giurgea, Michelle M. Kolberg, Brittany Heffelfinger, Matthew J. Memoli, Rachel Bean, Dominic Esposito, Matthew D. Hall, Monica Gouzoulis, Jennifer L. Hicks, Andrew Kelly, Barry I. Graubard, Susan Reed, Robert P. Kimberly, Sam Michael, Jacquelyn Spathies, Kaitlyn Sadtler, Rani Athota, Kelly Snead, Simon Messing, Adriana Cervantes-Medina, Jennifer A. Croker, Holly Ann Baus, Peter Frank, Michael P. Fay, Sally Hunsberger, Cheryl Chairez, Jennifer Mehalko, Tran B. Ngo, Eric W. Ford, William K. Gillette, Anandakumar Shunmugavel, Rocco Caldararo, Alison Han, John-Paul Denson, Heather Kalish
Publikováno v:
Science Translational Medicine
16.8 million SARS-CoV-2 infections in the US went undiagnosed in the first 6 months of the pandemic compared to 3.5 million diagnosed infections.
Elucidating seroprevalence in COVID-19 Symptoms of SARS-CoV-2 infection range from completely asymp
Elucidating seroprevalence in COVID-19 Symptoms of SARS-CoV-2 infection range from completely asymp