Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacquelyn M. Spence"'
Publikováno v:
Clinical Cancer Research. 17:6206-6217
Purpose: Cancer cells (relative to normal cells) show increased steady-state levels of hydroperoxides that are compensated by increased glucose and hydroperoxide metabolism. The current study determined whether inhibitors of glucose and hydroperoxide
Autor:
Samuel N. Rodman, Douglas R. Spitz, Melissa A. Fath, Rebecca A. O'Neill, Tyler J. Ronnfeldt, Jacquelyn M. Spence, Yueming Zhu, Shane R. Solst, Xiangming Guan, Bryan G. Allen
Publikováno v:
Radiation Research. 186:385
The current study determined if depletion of glutathione (GSH) and inhibition of thioredoxin reductase (TR) activity could enhance radiation responses in human breast cancer stem cells by a mechanism involving thiol dependent oxidative stress. Buthio