Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Jacquelyn Kilbourne"'
Autor:
Andrew G. Diamos, Mary D. Pardhe, Melissa H. Bergeman, Aigerim S. Kamzina, Michelle P. DiPalma, Sara Aman, Artemio Chaves, Kenneth Lowe, Jacquelyn Kilbourne, Ian B. Hogue, Hugh S. Mason
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIt has been known for over half a century that mixing an antigen with its cognate antibody in an immune complex (IC) can enhance antigen immunogenicity. However, many ICs produce inconsistent immune responses, and the use of ICs in the de
Externí odkaz:
https://doaj.org/article/9d33a692d17b4c849b36e64b619e6dfd
Autor:
John D. Christie, Nicole Appel, Hannah Canter, Jazmin Galvan Achi, Natalie M. Elliott, Ana Lemos de Matos, Lina Franco, Jacquelyn Kilbourne, Kenneth Lowe, Masmudur M. Rahman, Nancy Y. Villa, Joshua Carmen, Evelyn Luna, Joseph Blattman, Grant McFadden
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 539-554 (2021)
Solid cancers that metastasize to the lungs represent a major therapeutic challenge. Current treatment paradigms for lung metastases consist of radiation therapy, chemotherapies, and surgical resection, but there is no single treatment or combination
Externí odkaz:
https://doaj.org/article/ccbd0d437183457d9d022e1f440fa0a5
Autor:
Nancy.Y. Villa, Masmudur M. Rahman, Joseph. Mamola, Julia D’Isabella, Elizabeth Goras, Jacquelyn Kilbourne, Kenneth Lowe, Juliane Daggett-Vondras, Lino Torres, John Christie, Nicole Appel, Anna L. Cox, Jae B. Kim, Grant McFadden
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 171-188 (2020)
Multiple myeloma (MM) is a hematological malignancy of monoclonal plasma cells that remains incurable. Standard treatments for MM include myeloablative regimens and autologous cell transplantation for eligible patients. A major challenge of these tre
Externí odkaz:
https://doaj.org/article/9c0a4c2b6a54423791678350139e6911
Autor:
Isabela R. Zanetti, Michelle Burgin, Liqiang Zhang, Steve T. Yeh, Sriram Ambadapadi, Jacquelyn Kilbourne, Jordan R. Yaron, Kenneth M. Lowe, Juliane Daggett-Vondras, David Fonseca, Ryan Boyd, Dara Wakefield, William Clapp, Efrem Lim, Hao Chen, Alexandra Lucas
Publikováno v:
Pathogens, Vol 11, Iss 5, p 588 (2022)
Immune cell invasion after the transplantation of solid organs is directed by chemokines binding to glycosaminoglycans (GAGs), creating gradients that guide immune cell infiltration. Renal transplant is the preferred treatment for end stage renal fai
Externí odkaz:
https://doaj.org/article/bbb724add4e147c6b3a43ea6381638af
Autor:
Andrew G. Diamos, Mary D. Pardhe, Haiyan Sun, Joseph G. L. Hunter, Jacquelyn Kilbourne, Qiang Chen, Hugh S. Mason
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Therapeutics based on fusing a protein of interest to the IgG Fc domain have been enormously successful, though fewer studies have investigated the vaccine potential of IgG fusions. In this study, we systematically compared the key properties of seve
Externí odkaz:
https://doaj.org/article/acc80e1abe3f4a6dbd055da1af84faa3
Autor:
Jordan R. Yaron, Liqiang Zhang, Qiuyun Guo, Enkidia A. Awo, Michelle Burgin, Lauren N. Schutz, Nathan Zhang, Jacquelyn Kilbourne, Juliane Daggett-Vondras, Kenneth M. Lowe, Alexandra R. Lucas
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1003 (2020)
Complex dermal wounds represent major medical and financial burdens, especially in the context of comorbidities such as diabetes, infection and advanced age. New approaches to accelerate and improve, or “fine tune” the healing process, so as to i
Externí odkaz:
https://doaj.org/article/bfaa26eaa12e4063b99f3967df733055
Autor:
Zachary R Stromberg, James R Johnson, John M Fairbrother, Jacquelyn Kilbourne, Angelica Van Goor, Roy Curtiss, Melha Mellata
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180599 (2017)
Extraintestinal pathogenic Escherichia coli (ExPEC) strains are important pathogens that cause diverse diseases in humans and poultry. Some E. coli isolates from chicken feces contain ExPEC-associated virulence genes, so appear potentially pathogenic
Externí odkaz:
https://doaj.org/article/d232f96e52664329a2b019e8ef46f999
Autor:
Sarah A Kessans, Mark D Linhart, Lydia R Meador, Jacquelyn Kilbourne, Brenda G Hogue, Petra Fromme, Nobuyuki Matoba, Tsafrir S Mor
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151842 (2016)
It is widely anticipated that a prophylactic vaccine may be needed to control the HIV/AIDS epidemic worldwide. Despite over two decades of research, a vaccine against HIV-1 remains elusive, although a recent clinical trial has shown promising results
Externí odkaz:
https://doaj.org/article/f4351c501c2b4ea6bbd95c4fc6a17706
Autor:
Jiseon Yang, Jennifer Barrila, Kenneth L Roland, Jacquelyn Kilbourne, C Mark Ott, Rebecca J Forsyth, Cheryl A Nickerson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003839 (2015)
A distinct pathovar of Salmonella enterica serovar Typhimurium, ST313, has emerged in sub-Saharan Africa as a major cause of fatal bacteremia in young children and HIV-infected adults. D23580, a multidrug resistant clinical isolate of ST313, was prev
Externí odkaz:
https://doaj.org/article/53646b173d604a93bc53f549b329ac75
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59159 (2013)
Concerns about the safety of paralytics such as succinylcholine to facilitate endotracheal intubation limit their use in prehospital and emergency department settings. The ability to rapidly reverse paralysis and restore respiratory drive would incre
Externí odkaz:
https://doaj.org/article/65f516881b0041f1a49af9d9b42c4d85