Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacqueline Y. Channon Smith"'
Autor:
Mark P. Burns, John Bechara, Jacqueline Y. Channon Smith, Charbel Moussa, Michaeline Hebron, Lanier Heyburn, Zhaoxia Li, Brent T. Harris, Irina Lonskaya, Charisse N. Winston
Publikováno v:
Journal of neurochemistry. 139(4)
The trans-activating response of DNA/RNA-binding protein (TDP)-43 pathology is associated with many neurodegenerative diseases via unknown mechanisms. Here, we use a transgenic mouse model over-expressing human wild-type neuronal TDP-43 to study the
Autor:
Jacqueline Y. Channon Smith, Christopher H. Cogbill, Linda Kingman, Elijah W. Stommel, Camilo E. Fadul, Todd Mackenzie, Jeffrey A. Cohen, David J. Graber, Brent T. Harris
Publikováno v:
Amyotrophic Lateral Sclerosis. 10:393-404
Neuroinflammation through the cytokine, tumor necrosis factor-alpha (TNF-alpha) is thought to play an important role in the pathogenesis of amyotrophic lateral sclerosis (ALS). We conducted a preliminary phase II trial of thalidomide, which reduces l