Výsledky vyhledávání - "Jacqueline Vu"

Akademický článek

Clinical Implications of Combinatorial Pharmacogenomic Tests Based on Cytochrome P450 Variant Selection

Autor: Michael Sayer, Ashley Duche, Trang Jenny Tran Nguyen, Michelle Le, Kunj Patel, Jacqueline Vu, Danny Pham, Brianne Vernick, Richard Beuttler, Don Roosan, Moom R. Roosan

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Despite the potential to improve patient outcomes, the application of pharmacogenomics (PGx) is yet to be routine. A growing number of PGx implementers are leaning toward using combinatorial PGx (CPGx) tests (i.e., multigene tests) that are reusable

Externí odkaz: https://doaj.org/article/fc42852b2410449fbbbba1604d63cec0

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Akademický článek

Randomized, open-label, phase 2 study of nivolumab plus ipilimumab or nivolumab monotherapy in patients with advanced or metastatic solid tumors of high tumor mutational burden

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)

Background Checkpoint inhibitor therapy has demonstrated overall survival benefit in multiple tumor types. Tumor mutational burden (TMB) is a predictive biomarker for response to immunotherapies. This study evaluated the efficacy of nivolumab+ipilimu

Externí odkaz: https://doaj.org/article/be397a2c9d104c41b010a59bc9500941

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Akademický článek

Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies

Publikováno v: npj Precision Oncology, Vol 5, Iss 1, Pp 1-11 (2021)

Abstract In a pilot study, we evaluated the feasibility of real-time deep analysis of serial tumor samples from triple negative breast cancer patients to identify mechanisms of resistance and treatment opportunities as they emerge under therapeutic s

Externí odkaz: https://doaj.org/article/6f75a6bf3b4848219df5905c62072ab5

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Genetic Variability in Resistance of Creole Goats to Natural Infection with Trichostrongylids in Guadeloupea

Autor: Jacques Bouix, L. Gruner, Jacqueline Vu Tien Khang, J. Fleury, G. Aumont, Nathalie Mandonnet

Publikováno v: Annals of the New York Academy of Sciences. 791:421-431

The objective of this study was to show the existence of genetic variability in resistance of Creole goats to natural infection with intestinal nematodes. Four successive cohorts of male and female kids were reared from weaning during 9 months in int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4968855498ceb52b6dde0d36266e90aa
https://doi.org/10.1111/j.1749-6632.1996.tb53549.x

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Nematode parasites and scrapie: experiments in sheep and mice

Autor: Hervé Leroux, Jean Claude Caritez, Olivier Andreoletti, Philippe Jacquiet, Jacques Cortet, F. Eychenne, Pierre Sarradin, Nicolas Richer, L. Gruner, Jean-Michel Elsen, Jacqueline Vu Tien Khang

Publikováno v: Parasitology Research
Parasitology Research, Springer Verlag (Germany), 2004, 93, pp.493-498

To demonstrate the possible role of nematode parasites in the modification of host susceptibility to scrapie, experiments were conducted using sheep naturally exposed to scrapie, chosen by their genotype at the PrP gene, and infected with Teladorsagi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f9d463e0db5f302970f2fcbc5a1ac4
https://hal.inrae.fr/hal-02673496

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A short-term divergent selection for resistance to Teladorsagia circumcincta in Romanov sheep using natural or artificial challenge

Autor: F. Eychenne, Claude Limouzin, Jacqueline Vu Tien Khang, Christine Sauvé, L. Gruner, Jacques Cortet, Jacques Bouix, Nathalie Mandonnet

Publikováno v: Genetics Selection Evolution
Genetics Selection Evolution, BioMed Central, 2004, 36 (2), pp.217-242. ⟨10.1051/gse:2003060⟩
Genetics Selection Evolution, Vol 36, Iss 2, Pp 217-242 (2004)
Genetics Selection Evolution (36), 217-242. (2004)
Genetics, Selection, Evolution : GSE

This experiment was conducted to assess the efficiency of selection on the basis of response to artificial challenges in order to breed sheep resistant to natural infection. A short-term divergent selection process was designed to estimate the geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9423dba5c5113b18edeec5cfa6413302
https://hal.archives-ouvertes.fr/hal-00894483

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Assessment of genetic variability of resistance to gastrointestinal nematode parasites in Creole goats in the humid tropics

Autor: G. Aumont, Nathalie Mandonnet, L. Gruner, H. Varo, Jacqueline Vu Tien Khang, Rémy Arquet, Jacques Bouix, J. Fleury

Publikováno v: Journal of Animal Science
Journal of Animal Science, American Society of Animal Science, 2001, 79, pp.1706-1712

Goat production is widespread in the tropics. Goats are very susceptible to gastrointestinal nematode infection, but there is less evidence of their genetic resistance. Genetic resistance of Creole goats to gastrointestinal nematodes has been studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9780bdc8c5e0b0457e3a32ff8397dfef
https://hal.inrae.fr/hal-02680772

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Genetique de l'hote et resistance aux maladies infectieuses et parasitaires. Bilan de l'action incitatrice programmee

Autor: Frederic Lantier, Jacqueline Vu Tien Khang Bourgoin

Publikováno v: Genetique de l'hote et resistance aux maladies infectieuses et parasitaires
Genetique de l'hote et resistance aux maladies infectieuses et parasitaires, Apr 1990, Maisons-Alfort, France
HAL
Annales de Recherches Vétérinaires
Annales de Recherches Vétérinaires, INRA Editions, 1990, 21 (4), pp.291-308

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f3a01bd66925b2f56be6c7d895e2322b
https://hal.inrae.fr/hal-02845638

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