In vivo gadolinium nanoparticle quantification with SPECT/CT

Autor: Olga Kochebina, Adrien Halty, Jacqueline Taleb, David Kryza, Marc Janier, Alexandre Bani Sadr, Thomas Baudier, Simon Rit, David Sarrut

Publikováno v: EJNMMI Physics, Vol 6, Iss 1, Pp 1-15 (2019)

Abstract Background Gadolinium nanoparticles (Gd-NP) combined with radiotherapy are investigated for radiation dose enhancement in radiotherapy treatment. Indeed, NPs concentrated in a tumor could enhance its radiosensitization. The noninvasive quant

Externí odkaz: https://doaj.org/article/0d7cd6dad8124e118ee559465e944429

Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas

Autor: Marc Janier, Elsa Charignon, Catherine Savona-Baron, Jean Jacques Toulmé, Pauline Bonazza, Aref Hassan, Philippe Fernandez, Laurent Azéma, Olivier Paurelle, F. Debordeaux, David Kryza, Jacqueline Taleb, Jürgen Schulz

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2020, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
PLoS ONE, Public Library of Science, 2016, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
PLoS ONE, Vol 11, Iss 2, p e0149387 (2016)
PLoS ONE, 2020, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩

International audience; The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508a71d23191eec2fbe33900fe3c1507
https://hal.archives-ouvertes.fr/hal-02139130

Granulocyte Colony-Stimulating Factor Nanocarriers for Stimulation of the Immune System (Part I): Synthesis and Biodistribution Studies

Autor: Gloria Jiménez Sánchez, Doriane Mathé, Charles Dumontet, David Kryza, Carole Chaix, Stéphane Roux, Jacqueline Taleb, Gabriel De Crozals, Marc Janier

Publikováno v: Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2018, 29 (3), pp.795-803. 〈10.1021/acs.bioconjchem.7b00605〉
Bioconjugate Chemistry, American Chemical Society, 2018, 29 (3), pp.795-803. ⟨10.1021/acs.bioconjchem.7b00605⟩

In the field of cancer immunotherapy, an original approach consists of using granulocyte colony-stimulating factor (G-CSF) to target and activate neutrophils, cells of the innate immune system. G-CSF is a leukocyte stimulating molecule which is commo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad092c8595c9387d7d988afede45a58
https://doi.org/10.1021/acs.bioconjchem.7b00605

Quantification of Gd-Nanoparticles Concentration with SPECT and Spectral Photon Counting CT

Autor: Jacqueline Taleb, David Sarrut, Marc Janier T, Cyril Mory, Philippe Douek, Simon Rit, Alexandre Bani Sadr T, Thomas Baudier, Adrien Halty, Olga Kochebina, Daniel Bar-Ness, David Kryza T

Publikováno v: 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).

Gadolinium nanoparticles (NP) combined with conventional radiotherapy could be used for oncology treatment.Indeed, NPs concentrated in a tumor could enhance its radiosensitization. The noninvasive quantification of NP concentration is a crucial task

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a9368eb3264974031288f9fbd50c898
https://doi.org/10.1109/nssmic.2017.8532980

Mastering the Shape and Composition of Dendronized Iron Oxide Nanoparticles To Tailor Magnetic Resonance Imaging and Hyperthermia

Autor: Lenaic Lartigue, Sophie Laurent, Claire Billotey, Robert N. Muller, Aurélie Walter, Luce Vander Elst, Antonio Garofalo, Jacqueline Taleb, Corinne Ulhaq-Bouillet, Florence Gazeau, Sylvie Begin-Colin, Delphine Felder-Flesch, Christophe Lefevre

Publikováno v: Chemistry of Materials
Chemistry of Materials, American Chemical Society, 2014, 26, pp.5252-5264. ⟨10.1021/cm5019025⟩

The current challenge in the field of nano-medicine is the design of multifunctional nano-objects effective both for the diagnosis and treatment of diseases. Here, dendronized FeO1-x@Fe3-xO4 nanoparticles with spherical, cubic, and octopode shapes an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678f7ab61c726e271d6977fdb0e305ea
https://doi.org/10.1021/cm5019025