Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jacqueline T. Chen"'
Autor:
Yuntian Xue, Andrew W. Browne, William C. Tang, Jeffrey Delgado, Bryce T. McLelland, Gabriel Nistor, Jacqueline T. Chen, Kaylee Chew, Nicolas Lee, Hans S. Keirstead, Magdalene J. Seiler
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Pluripotent stem cell-derived organoid technologies have opened avenues to preclinical basic science research, drug discovery, and transplantation therapy in organ systems. Stem cell-derived organoids follow a time course similar to species-specific
Externí odkaz:
https://doaj.org/article/e90d591acb7f402895d13763d2ab839a
Autor:
Jian Lin, Scott F. Lempka, Erik B. Beall, Andre G. Machado, Xuemei Huang, Mark J. Lowe, Raghavan Gopalakrishnan, Stephen E. Jones, Jacqueline T. Chen, Donald A. Malone, Kenneth B. Baker, Pallab K. Bhattacharyya
Publikováno v:
Neuromodulation: Technology at the Neural Interface. 24:259-264
OBJECTIVE Deep brain stimulation (DBS) for pain has largely been implemented in an uncontrolled manner to target the somatosensory component of pain, with research leading to mixed results. We have previously shown that patients with poststroke pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0857a3672088831f8b045cdffe8458
https://doi.org/10.1111/ner.13247
https://doi.org/10.1111/ner.13247
Autor:
Harsha Battapady, Anthony M. Chomyk, Grahame J. Kidd, Ranjan Dutta, Ricky Chan, Selva Baltan, Bruce D. Trapp, Safdar Jawaid, Jacqueline T. Chen
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Cognitive dysfunction occurs in greater than 50% of individuals with multiple sclerosis (MS). Hippocampal demyelination is a prominent feature of postmortem MS brains and hippocampal atrophy correlates with cognitive decline in MS patients. Cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049c839841da54144ead6f6fb5e904a6
https://pubmed.ncbi.nlm.nih.gov/33648591
https://pubmed.ncbi.nlm.nih.gov/33648591
Autor:
Mykol Larvie, Jeffery L Cummings, Stephen E. Jones, Jagan A. Pillai, Jacqueline T. Chen, Anna Crawford
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
To estimate regional Alzheimer disease (AD) pathology burden clinically, analysis methods that enable tracking brain amyloid or tau positron emission tomography (PET) with magnetic resonance imaging (MRI) measures are needed. We therefore developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3453804fe6cc5ee886773e3095c0a37a
http://europepmc.org/articles/PMC7693188
http://europepmc.org/articles/PMC7693188
Autor:
Jacqueline T. Chen, Daniel Ontaneda, Kunio Nakamura, Harsha Battapady, Stephen E. Jones, Jessica Dudman, Robert J. Fox, Sverre Mørk, Richard A. Rudick, Bruce D. Trapp, Susan M. Staugaitis, Elizabeth Fisher, Megan C. Vignos, Ansi Chang
Publikováno v:
The Lancet Neurology. 17:870-884
Summary Background Demyelination of cerebral white matter is thought to drive neuronal degeneration and permanent neurological disability in individuals with multiple sclerosis. Findings from brain MRI studies, however, support the possibility that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058d47b2cf701eb6d348ac07a964bd94
https://doi.org/10.1016/s1474-4422(18)30245-x
https://doi.org/10.1016/s1474-4422(18)30245-x
Autor:
Ranjan Dutta, Christina Volsko, Jessica Dudman, Bruce D. Trapp, Kedar R Mahajan, Kunio Nakamura, Daniel Ontaneda, Robert J. Fox, Jacqueline T. Chen, Jordon Dunham, Emilie Christie
Publikováno v:
Journal of Visualized Experiments.
We describe a rapid tissue donation program for individuals with multiple sclerosis (MS) that requires scientists and technicians to be on-call 24/7, 365 days a year. Participants consent to donate their brain and spinal cord. Most patients were foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142ecf39ad753491773d74289281d05c
https://doi.org/10.3791/59511
https://doi.org/10.3791/59511
Autor:
Robert A. Brown, Sridar Narayanan, Harold L. Atkins, Hyun-Woo Lee, Jacqueline T. Chen, Mark S. Freedman, Douglas L. Arnold
Publikováno v:
Multiple Sclerosis Journal. 23:420-431
Background: A cohort of patients with poor-prognosis multiple sclerosis (MS) underwent chemotherapy-based immune ablation followed by immune reconstitution with an autologous hematopoietic stem cell transplant (IA/aHSCT). This eliminated new focal in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04a5e71fd4f9156b6edfef11fb2ebd6
https://doi.org/10.1177/1352458516650992
https://doi.org/10.1177/1352458516650992
Publikováno v:
Radiology. 287(3)
PURPOSE: To determine if magnetic resonance (MR) imaging metrics can estimate primary motor cortex (PMC) motor neuron (MN) density in patients with amyotrophic lateral sclerosis (ALS). MATERIALS AND METHODS: Between 2012 and 2014, in situ brain MR im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e958f3ce0dffa72e21c4ef15e464a6ee
https://pubmed.ncbi.nlm.nih.gov/29361242
https://pubmed.ncbi.nlm.nih.gov/29361242
Autor:
John T. Gale, Jacqueline T. Chen, Clarissa Martinez-Rubio, Zhihong Chen, Megan Hendrickson, Zachary C. Gossman, Bruce D. Trapp, Kenneth Earl Sakaie, Matthew D. Johnson
Publikováno v:
Annals of Clinical and Translational Neurology
Cognitive decline is a common symptom in multiple sclerosis patients, with profound effects on the quality of life. A nonhuman primate model of multiple sclerosis would be best suited to test the effects of demyelination on complex cognitive function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e4f70b80c25b236e204d2b39698f45
https://doi.org/10.1002/acn3.159
https://doi.org/10.1002/acn3.159
Publikováno v:
Annals of neurology. 82(4)
Detecting cortical demyelination in patients with multiple sclerosis (MS) is difficult. Using magnetic resonance imaging (MRI), ratio maps of T1-weighted (T1w) and T2-weighted (T2w) images may be sensitive to cortical myelin levels. In this MRI-histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5863b21b3705e75cf4d6b7abb41eae59
https://pubmed.ncbi.nlm.nih.gov/28976603
https://pubmed.ncbi.nlm.nih.gov/28976603