Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jacqueline T, Balthazar"'
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Understanding how bacteria adapt to different environmental conditions is crucial for advancing knowledge regarding pathogenic mechanisms that operate during infection as well as efforts to develop new therapeutic strategies to cure or preve
Externí odkaz:
https://doaj.org/article/bb2ccfc2c91643afbac9232e87024e21
Autor:
Jacqueline T. Balthazar, Daniel Golparian, Magnus Unemo, Timothy D. Read, Miriam Grosse, Marc Stadler, Kenneth Pfarr, Andrea Schiefer, Achim Hoerauf, Jennifer L. Edwards, Dmitry G. Vassylyev, William M. Shafer
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/6b803d30307d4d6083f7d0b1b866983c
Autor:
Jacqueline T. Balthazar, Daniel Golparian, Magnus Unemo, Timothy D. Read, Miriam Grosse, Marc Stadler, Kenneth Pfarr, Andrea Schiefer, Achim Hoerauf, Jennifer L. Edwards, Dmitry G. Vassylyev, William M. Shafer
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT The continued emergence of Neisseria gonorrhoeae strains that express resistance to multiple antibiotics, including the last drug for empiric monotherapy (ceftriaxone), necessitates the development of new treatment options to cure gonorrheal
Externí odkaz:
https://doaj.org/article/48b85a00acda464f9f62ce8110ea29d7
Autor:
Jennifer L. Edwards, Jacqueline T. Balthazar, Danillo L. A. Esposito, Julio C. Ayala, Andrea Schiefer, Kenneth Pfarr, Achim Hoerauf, Silke Alt, Thomas Hesterkamp, Miriam Grosse, Marc Stadler, Daniel Golparian, Magnus Unemo, Timothy D. Read, William M. Shafer
Publikováno v:
mSphere, Vol 7, Iss 5 (2022)
ABSTRACT Gonorrhea remains a major global public health problem because of the high incidence of infection (estimated 82 million cases in 2020) and the emergence and spread of Neisseria gonorrhoeae strains resistant to previous and current antibiotic
Externí odkaz:
https://doaj.org/article/961e129f07f64b2fb61e13b4c0e7ef00
Autor:
Isabelle Leduc, Kristie L Connolly, Afrin Begum, Knashka Underwood, Stephen Darnell, William M Shafer, Jacqueline T Balthazar, Andrew N Macintyre, Gregory D Sempowski, Joseph A Duncan, Marguerite B Little, Nazia Rahman, Eric C Garges, Ann E Jerse
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1008602 (2020)
There is a pressing need for a gonorrhea vaccine due to the high disease burden associated with gonococcal infections globally and the rapid evolution of antibiotic resistance in Neisseria gonorrhoeae (Ng). Current gonorrhea vaccine research is in th
Externí odkaz:
https://doaj.org/article/74a38cc3d9d04837a751e9b443e7f5f5
Autor:
Corinne E. Rouquette-Loughlin, Jennifer L. Reimche, Jacqueline T. Balthazar, Vijaya Dhulipala, Kim M. Gernert, Ellen N. Kersh, Cau D. Pham, Kevin Pettus, A. Jeanine Abrams, David L. Trees, Sancta St Cyr, William M. Shafer
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Recent reports suggest that mosaic-like sequences within the mtr (multiple transferable resistance) efflux pump locus of Neisseria gonorrhoeae, likely originating from commensal Neisseria sp. by transformation, can increase the ability of go
Externí odkaz:
https://doaj.org/article/0768313d52f94a4392f3650a97098160
Publikováno v:
Microbiology. 168
This review focuses on the mechanisms of transcriptional control of an important multidrug efflux pump system (MtrCDE) possessed by Neisseria gonorrhoeae , the aetiological agent of the sexually transmitted infection termed gonorrhoea. The mtrCDE ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c5c561305f0ecbf14f6cbb54fe3692e
https://doi.org/10.1099/mic.0.001231
https://doi.org/10.1099/mic.0.001231
Autor:
Jennifer L. Edwards, Jacqueline T. Balthazar, Danillo L. A. Esposito, Julio C. Ayala, Andrea Schiefer, Kenneth Pfarr, Achim Hoerauf, Silke Alt, Thomas Hesterkamp, Miriam Grosse, Marc Stadler, Daniel Golparian, Magnus Unemo, Timothy D. Read, William M. Shafer
Publikováno v:
mSphere. 7(5)
Gonorrhea remains a major global public health problem because of the high incidence of infection (estimated 82 million cases in 2020) and the emergence and spread of Neisseria gonorrhoeae strains resistant to previous and current antibiotics used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d1cf2bae2c02220579d6d511572b88
https://pubmed.ncbi.nlm.nih.gov/36094073
https://pubmed.ncbi.nlm.nih.gov/36094073
Autor:
Corinne E. Rouquette-Loughlin, Yaramah M. Zalucki, Vijaya L. Dhulipala, Jacqueline T. Balthazar, Raúl G. Doyle, Robert A. Nicholas, Afrin A. Begum, Erica L. Raterman, Ann E. Jerse, William M. Shafer
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT The MtrCDE efflux pump of Neisseria gonorrhoeae contributes to gonococcal resistance to a number of antibiotics used previously or currently in treatment of gonorrhea, as well as to host-derived antimicrobials that participate in innate defe
Externí odkaz:
https://doaj.org/article/78a52acdff2b4e739aa56bb2bf870f78
Autor:
Concerta L. Holley, Vijaya Dhulipala, Jacqueline T. Balthazar, Adriana Le Van, Afrin A. Begum, Shao-Chun Chen, Timothy D. Read, Mitch Matoga, Irving F. Hoffman, Daniel Golparian, Magnus Unemo, Ann E. Jerse, William M. Shafer
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
The continued emergence of Neisseria gonorrhoeae isolates which are resistant to first-line antibiotics has reinvigorated interest in alternative therapies such as expanded use of gentamicin (Gen). We hypothesized that expanded use of Gen promotes em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdb480d36fed351e62870099d600305
https://doi.org/10.1128/aac.00251-22
https://doi.org/10.1128/aac.00251-22