Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jacqueline Seigner"'
Autor:
Jacqueline Seigner, Charlotte U. Zajc, Sarah Dötsch, Caroline Eigner, Elisabeth Laurent, Dirk H. Busch, Manfred Lehner, Michael W. Traxlmayr
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The majority of approved CAR T cell products are based on the FMC63-scFv directed against CD19. Surprisingly, although antigen binding affinity is a major determinant for CAR function, the affinity of the benchmark FMC63-scFv has not been un
Externí odkaz:
https://doaj.org/article/99196f542e2244e996021a41392220b3
Autor:
Jacqueline Seigner, Marc Junker-Samek, Alberto Plaza, Gilda D‘Urso, Milena Masullo, Sonia Piacente, Yvonne M. Holper-Schichl, Rainer de Martin
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Symphytum officinale, commonly known as comfrey, constitutes a traditional medicinal plant with a long-standing therapeutic history, and preparations thereof have been widely used for the treatment of painful muscle and joint complaints, wound and bo
Externí odkaz:
https://doaj.org/article/25cbae7a37574f719c337008680a5875
Autor:
Julia Zwirchmayr, Ulrike Grienke, Scarlet Hummelbrunner, Jacqueline Seigner, Rainer de Martin, Verena M. Dirsch, Judith M. Rollinger
Publikováno v:
Biomolecules, Vol 10, Iss 5, p 679 (2020)
Peucedanum ostruthium (L.) Koch, commonly known as masterwort, has a longstanding history as herbal remedy in the Alpine region of Austria, where the roots and rhizomes are traditionally used to treat disorders of the gastrointestinal and respiratory
Externí odkaz:
https://doaj.org/article/556bd074a838437caffa14046bf71b2b
Autor:
Anna Sieber, Bernhard Kratzer, Anna Wachernig, Michael W. Traxlmayr, Jacqueline Seigner, Manfred Lehner, Ulrich Jäger, Renate Kunert, Winfried F. Pickl, Elisabeth Laurent, René Geyeregger, Benjamin Salzer
Publikováno v:
ACS Synthetic Biology
CD19 is among the most relevant targets in cancer immunotherapy. However, its extracellular domain (ECD) is prone to aggregation and misfolding, representing a major obstacle for the development and analysis of CD19-targeted therapeutics. Here, we en
Autor:
Elisabeth Gadermaier, Emanuel Kreidl, Herwig P. Moll, Mario Rothbauer, Katharina Hammel, Azra Rogalli, Venugopal Bhaskara, Anton Bauer, Laura Stangl, Maria Trinidad Leal, Emilio Casanova, Rainer Hahn, Jacqueline Seigner, Jacqueline Wallwitz, Manfred Tesarz, Peter Ertl, Theresa Friedrich, Gottfried Himmler
Publikováno v:
Journal of biotechnology. 331
Despite the essential role secretory IgAs play in the defense against pathogenic invasion and the proposed value of recombinant secretory IgAs as novel therapeutics, currently there are no IgA-based therapies in clinics. Secretory IgAs are complex mo
Autor:
Jacqueline Seigner, Gilda D'Urso, Sonia Piacente, Alberto Plaza, Milena Masullo, Rainer de Martin, Yvonne M Holper-Schichl
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 13
International Journal of Molecular Sciences, Vol 21, Iss 4671, p 4671 (2020)
Volume 21
Issue 13
International Journal of Molecular Sciences, Vol 21, Iss 4671, p 4671 (2020)
Preparations of comfrey (Symphytum officinale L.) roots are used topically to reduce inflammation. Comfrey anti-inflammatory and analgesic properties have been proven in clinical studies. However, the bioactive compounds associated with these therape
Autor:
Scarlet Hummelbrunner, Ulrike Grienke, Jacqueline Seigner, Judith M. Rollinger, Verena M. Dirsch, Rainer de Martin, Julia Zwirchmayr
Publikováno v:
Biomolecules
Volume 10
Issue 5
Biomolecules, Vol 10, Iss 679, p 679 (2020)
Volume 10
Issue 5
Biomolecules, Vol 10, Iss 679, p 679 (2020)
Peucedanum ostruthium (L.) Koch, commonly known as masterwort, has a longstanding history as herbal remedy in the Alpine region of Austria, where the roots and rhizomes are traditionally used to treat disorders of the gastrointestinal and respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d497a64e10f0389382fb3652891b46
https://doi.org/10.3390/biom10050679
https://doi.org/10.3390/biom10050679
Autor:
Stefan Stojkovic, Gerald Maurer, Kurt Huber, Sabine Rauscher, Walter S. Speidl, Andreas Zuckermann, Wolfgang Eppel, Konstantin A. Krychtiuk, Johann Wojta, Philipp J. Hohensinner, Rainer de Martin, Jacqueline Seigner, Christoph Kaun, Stefan P. Kastl
Publikováno v:
Vascular Pharmacology. 90:44-50
Aims Levosimendan is an inodilator for the treatment of acute decompensated heart failure (HF). Data from clinical studies suggest that levosimendan is particularly effective in HF due to myocardial infarction. After acute revascularization, no reflo