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pro vyhledávání: '"Jacqueline Schütt"'
Autor:
Zeinab Waad Sadiq, Annamaria Brioli, Ruba Al-Abdulla, Gonca Çetin, Jacqueline Schütt, Hugo Murua Escobar, Elke Krüger, Frédéric Ebstein
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionProteasome inhibition is first line therapy in multiple myeloma (MM). The immunological potential of cell death triggered by defects of the ubiquitin-proteasome system (UPS) and subsequent perturbations of protein homeostasis is, however,
Externí odkaz:
https://doaj.org/article/44ee289e92e843e7a537f94d8279f0b3
Publikováno v:
Cancers, Vol 13, Iss 16, p 4069 (2021)
Multiple Myeloma (MM) is a malignancy of plasma cells infiltrating the bone marrow (BM). Many studies have demonstrated the crucial involvement of bone marrow stromal cells in MM progression and drug resistance. Together with the BM microenvironment
Externí odkaz:
https://doaj.org/article/223188dc44644542a65227acc331ae90
Publikováno v:
Cancers, Vol 13, Iss 4069, p 4069 (2021)
Cancers
Cancers
Simple Summary Despite advances made in the last two decades, multiple myeloma (MM) is still an incurable disease. The genetic complexity of MM and the presence of intra-clonal heterogeneity are major contributors to disease relapse and the developme