Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jacqueline Sawyer"'
Autor:
Wilson O. Endege, Jun Xian, Joseph Pearlberg, Joan E. Davies, Yanhui Hu, Sebastien Degot, John G. Doench, Karl Münger, Jacqueline Sawyer, Ed Harlow, Dorre A. Grueneberg, Frederick M. Boyce, Wenliang Li, Amy Baldwin
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16472-16477
shRNA loss-of-function screens were used to identify kinases that were rate-limiting for promoting cell proliferation and survival. Here, we study the differences in kinase requirements among various human cells, including freshly prepared primary ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f525b7dc091e8b108c10557b2de48b
https://doi.org/10.1073/pnas.0808019105
https://doi.org/10.1073/pnas.0808019105
Autor:
Joseph Pearlberg, Dorre A. Grueneberg, Ed Harlow, Wenliang Li, Jacqueline Sawyer, Joan E. Davies
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16490-16495
Functional differences among human cells have been difficult to identify by standard biochemical methods. Loss-of-function shRNA screens provide an unbiased method to compare protein requirements across cell lines. In previous work, we have studied k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7d18b0ba50465a1fc26d1c4a0714b8
https://doi.org/10.1073/pnas.0806578105
https://doi.org/10.1073/pnas.0806578105
Publikováno v:
Lancet (London, England). 386(10010)
1 The Lancet. Snake bite—the neglected tropical disease. Lancet 2015; 386: 1110. 2 Mechanisms to reverse the public health neglect of snakebite victims; Wellcome Trust Genome Campus, Hinxton, Cambridge, UK; Sept 22–23, 2015. 3 WHO. WHO model list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421e120786dc99def293181fb071cdbc
https://pubmed.ncbi.nlm.nih.gov/26461887
https://pubmed.ncbi.nlm.nih.gov/26461887
Autor:
Leonardo Brizuela, Ed Harlow, Joshua LaBaer, Wenliang Li, Jacqueline Sawyer, L. Gonzalez, John G. Doench, Wilson O. Endege, Dorre A. Grueneberg, Frederick M. Boyce, E. Gelfand, Andrew R. Conery, S. Degot, Jaehong Park, Julian Davies, Joseph Pearlberg
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 70:449-459
We have developed methods for the automation of transfection-grade DNA preparation, high-throughput retroviral preparation, and highly parallel phenotypic screens to establish approaches that will allow investigators to examine in an unbiased manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed4fc67b01fb8dd14b0ca3746118a9b
https://doi.org/10.1101/sqb.2005.70.047
https://doi.org/10.1101/sqb.2005.70.047
Autor:
Jacqueline Sawyer, Miranda Grace, Karin Hellner, Ed Harlow, Karl Münger, Amy Baldwin, Wenliang Li, Dorre A. Grueneberg
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(28)
Cervical carcinomas are initiated through a series of well-defined stages that rely on the expression of human papillomavirus (HPV) oncogenes. A panel of 100 small hairpin RNAs that target essential kinases in many tumor types was used to study the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8b938d5ee2b052df0c2576a3100220
http://ora.ox.ac.uk/objects/uuid:5df18455-6aa6-4207-81c6-8233d72f222b
http://ora.ox.ac.uk/objects/uuid:5df18455-6aa6-4207-81c6-8233d72f222b
Autor:
Christoph Geisen, Ingrid Almeciga, Archana Bommi-Reddy, William G. Kaelin, Jacqueline Sawyer, Wenliang Li, Ed Harlow, Dorre A. Grueneberg
Clear cell renal carcinomas are the most common form of kidney cancer and frequently are linked to biallelic inactivation of the von Hippel-Lindau ( VHL ) tumor suppressor gene. The VHL gene product, pVHL, has multiple functions including directing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8387c8b290b8db606f06a22ae4545df8
https://europepmc.org/articles/PMC2575446/
https://europepmc.org/articles/PMC2575446/
Publikováno v:
The Lancet. 376:958
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f1e5a6745907cadb7ab45cc1bd435e
https://doi.org/10.1016/s0140-6736(10)61451-1
https://doi.org/10.1016/s0140-6736(10)61451-1
Autor:
Jacqueline Sawyer
Publikováno v:
The Conservation Atlas of Tropical Forests Africa ISBN: 9781349129638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a8ace7b3d6be3c36736dbd4be841b80
https://doi.org/10.1007/978-1-349-12961-4_7
https://doi.org/10.1007/978-1-349-12961-4_7
Publikováno v:
BMJ. 332:1393.3-1394
EDITOR—The BMJ news item on adverse drug reactions is important.1 The estimated annual expenditure of $870m towards issues related to such effects would be hard on any economy; such figures could seriously cripple countries with lesser resources. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd1a396d4caa4cca56700f6bd467144
https://doi.org/10.1136/bmj.332.7554.1393-b
https://doi.org/10.1136/bmj.332.7554.1393-b