Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jacqueline Salotti"'
Autor:
Martin Panigaj, Elizabeth Skelly, Damian Beasock, Ian Marriott, M. Brittany Johnson, Jacqueline Salotti, Kirill A. Afonin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between “self” and “non-self”. In addition, it guards us against other diseases, such as cancer, by
Externí odkaz:
https://doaj.org/article/71bd4674418d489b88e82c9f888263ff
Autor:
Taejin Kim, Mathias Viard, Kirill A. Afonin, Kshitij Gupta, Mary Popov, Jacqueline Salotti, Peter F. Johnson, Charles Linder, Eliahu Heldman, Bruce A. Shapiro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 20, Iss , Pp 359-372 (2020)
Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However,
Externí odkaz:
https://doaj.org/article/bb90cca83bf74e98a8a3fce08ace1da7
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72582 (2013)
We recently reported that paracrine Fibroblast Growth Factor 2 (FGF2) triggers senescence in Ras-driven Y1 and 3T3(Ras) mouse malignant cell lines. Here, we show that although FGF2 activates mitogenic pathways in these Ras-dependent malignant cells,
Externí odkaz:
https://doaj.org/article/2b2005f78c3847f28f1e214556ed7b21
Autor:
Jacqueline Salotti
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Descrevemos, recentemente, que FGF2 parácrino dispara senescência nas linhagens celulares murinas Y1 e 3T3-B61, transformadas malignamente por Ras, mas sem ativação das vias apoptóticas (Costa et al., 2008). Nesta tese, estudamos os mecanismos c
Autor:
Peter F. Johnson, Deborah K. Morrison, Christopher J. Westlake, Vijay Walia, Zhen Xiao, Krisada Sakchaisri, Srikanta Basu, Jacqueline Salotti, Sook Lee, Sandip K. Basu
The precise characteristics that distinguish normal and oncogenic RAS signaling remain obscure. Here, we show that oncogenic RAS and BRAF induce perinuclear relocalization of several RAS pathway proteins, including the kinases CK2 and p-ERK1/2 and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1336c8de8a1834a03f4ae092e99881bb
https://doi.org/10.1158/0008-5472.c.6509903.v1
https://doi.org/10.1158/0008-5472.c.6509903.v1
Autor:
Peter F. Johnson, Deborah K. Morrison, Christopher J. Westlake, Vijay Walia, Zhen Xiao, Krisada Sakchaisri, Srikanta Basu, Jacqueline Salotti, Sook Lee, Sandip K. Basu
Supplementary Figures S1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8a43545514d454bf8bd349259ad427
https://doi.org/10.1158/0008-5472.22417649.v1
https://doi.org/10.1158/0008-5472.22417649.v1
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Supplementary Table 1 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4ba71128b7d5124591139e92b6084f
https://doi.org/10.1158/0008-5472.22374059
https://doi.org/10.1158/0008-5472.22374059
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Supplementary Figures 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514848a91f63cd0e2e0d45bdb51175ac
https://doi.org/10.1158/0008-5472.22374062
https://doi.org/10.1158/0008-5472.22374062
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Fibroblast growth factor 2 (FGF2) is considered to be a bona fide oncogenic factor, although results from our group and others call this into question. Here, we report that exogenous recombinant FGF2 irreversibly inhibits proliferation by inducing se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df18ccea0863a760d7c022c9cf65eed7
https://doi.org/10.1158/0008-5472.c.6497321
https://doi.org/10.1158/0008-5472.c.6497321
Autor:
Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa
Supplementary Figure Legends 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5953fad9222df4f80db09aff5e10e498
https://doi.org/10.1158/0008-5472.22374065.v1
https://doi.org/10.1158/0008-5472.22374065.v1