Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jacqueline R Dauch"'
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192333 (2018)
Painful neuropathy (PN) is a prevalent condition in patients with metabolic syndrome (MetS). However, the pathogenic mechanisms of metabolic syndrome-associated painful neuropathy (MetSPN) remain unclear. In the current study, high-fat-fed mice (HF m
Externí odkaz:
https://doaj.org/article/89b5740522cf43c588d8414a0a7b43c5
Autor:
Catrina Sims-Robinson, Junguk Hur, John M Hayes, Jacqueline R Dauch, Peter J Keller, Susan V Brooks, Eva L Feldman
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68011 (2013)
While oxidative stress is implicated in aging, the impact of oxidative stress on aging in the peripheral nervous system is not well understood. To determine a potential mechanism for age-related deficits in the peripheral nervous system, we examined
Externí odkaz:
https://doaj.org/article/8acd5e6c307a40c99f6352279bd72a26
Autor:
Sarah E. Elzinga, Stephanie A. Eid, Brett A. McGregor, Dae-Gyu Jang, Lucy M. Hinder, Jacqueline R. Dauch, John M. Hayes, Hongyu Zhang, Kai Guo, Subramaniam Pennathur, Matthias Kretzler, Frank C. Brosius, Emily J. Koubek, Eva L. Feldman, Junguk Hur
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/d240158514aa40fe8b66d99c549dc073
Interleukin-10 Reduces Neurogenic Inflammation and Pain Behavior in a Mouse Model of Type 2 Diabetes
Publikováno v:
Journal of Pain Research
Brandon M Yanik,1 Jacqueline R Dauch,1 Hsinlin T Cheng1,2 1Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan, USA; 2Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachuset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7691509739e0b10e250b44479cac565
https://doi.org/10.2147/jpr.s264136
https://doi.org/10.2147/jpr.s264136
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 1, Pp 280-287 (2012)
Painful diabetic neuropathy (PDN) is a common, yet devastating complication of type 2 diabetes. At this time, there is no objective test for diagnosing PDN. In the current study, we measured the peptidergic intraepidermal nerve fiber densities (IENFD
Externí odkaz:
https://doaj.org/article/7fd534d2359147d6bab934c444d8a1e9
Autor:
Eva L. Feldman, Lucy M. Hinder, Carey Backus, John M. Hayes, Jacqueline R. Dauch, Faye E. Mendelson, Amy E. Rumora, Phillipe D. O'Brien
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Peripheral neuropathy (neuropathy) is a common complication of obesity and type 2 diabetes in children and adolescents. To model this complication in mice, 5-week-old male C57BL/6J mice were fed a high-fat diet to induce diet-induced obesity (DIO), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fe0ca52402cd7dd07b741d497dd07c
https://pubmed.ncbi.nlm.nih.gov/30446513
https://pubmed.ncbi.nlm.nih.gov/30446513
Autor:
Junguk Hur, Carey Backus, John M. Hayes, Frank C. Brosius, Matthias Kretzler, Jacqueline R. Dauch, Eva L. Feldman, Lucy M. Hinder, Subramaniam Pennathur
Publikováno v:
Diabetes
To define the components of the metabolic syndrome that contribute to diabetic polyneuropathy (DPN) in type 2 diabetes mellitus (T2DM), we treated the BKS db/db mouse, an established murine model of T2DM and the metabolic syndrome, with the thiazolid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f86e74c5f899fd70000a1eab49ef0d2
https://doi.org/10.2337/db15-0133
https://doi.org/10.2337/db15-0133
Autor:
Brandon M. Yanik, J. Robinson Singleton, Michael T. Porzio, Wilson Hsieh, Jacqueline R. Dauch, Eva L. Feldman, A. Gordon Smith, Hsinlin T. Cheng
Publikováno v:
The Journal of Pain. 14:941-947
We examined changes in intraepidermal nerve fibers (IENFs) to differentiate patients with diabetic neuropathy (DN) and diabetic neuropathic pain (DN-P) from those with DN without pain (DN-NOP). Punch skin biopsies were collected from the proximal thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1707bae24aef91be5138a7560805a0e
https://doi.org/10.1016/j.jpain.2013.03.005
https://doi.org/10.1016/j.jpain.2013.03.005
Publikováno v:
Molecular Pain
Molecular Pain, Vol 6, Iss 1, p 28 (2010)
Molecular Pain, Vol 6, Iss 1, p 28 (2010)
Background: Painful Diabetic Neuropathy (PDN) affects more than 25% of patients with type 2 diabetes; however, the pathogenesis remains unclear due to lack of knowledge of the molecular mechanisms leading to PDN. In our current study, we use an anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9c9dca66bb2823ea472af050764d88
https://doi.org/10.1186/1744-8069-6-28
https://doi.org/10.1186/1744-8069-6-28
Autor:
Diane E. Bender, Hsinlin T. Cheng, Zachary A Kelly, Jacqueline R. Dauch, Wilson Hsieh, Lucía A Luna-Wong, Brandon M. Yanik
Publikováno v:
Journal of Neuroinflammation
Background Langerhans cells (LCs) are antigen-presenting dendritic cells located in the skin. It has been reported that LC activation is associated with painful diabetic neuropathy (PDN); however, the mechanism of LC activation is still unclear. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0975e99bb9f7ef0039710760ab1b44
https://doi.org/10.1186/1742-2094-10-64
https://doi.org/10.1186/1742-2094-10-64