Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jacqueline Perrigoue"'
Autor:
Roman Kosoy, Seunghee Kim-Schulze, Adeeb Rahman, Joshua R. Friedman, Ruiqi Huang, Lauren A. Peters, El-ad Amir, Jacqueline Perrigoue, Aleksandar Stojmirovic, Won-min Song, Hao Ke, Ryan Ungaro, Saurabh Mehandru, Judy Cho, Marla Dubinsky, Mark Curran, Carrie Brodmerkel, Eric E. Schadt, Bruce E. Sands, Jean-Frederic Colombel, Andrew Kasarskis, Carmen A. Argmann, Mayte Suárez-Fariñas
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 599-632 (2021)
Background: Inflammatory bowel disease (IBD) is a complex disease with variable presentation, progression, and response to therapies. Current disease classification is based on subjective clinical phenotypes. The peripheral blood immunophenome can re
Externí odkaz:
https://doaj.org/article/ce39650906404858884de64148570f38
Autor:
Adeeb Rahman, Aleksandar Stojmirović, Marla Dubinsky, Eric E. Schadt, Ryan C. Ungaro, Lauren A. Peters, Joshua R. Friedman, Roman Kosoy, Judy H. Cho, Won-Min Song, Mark Curran, Ruiqi Huang, Jean-Frederic Colombel, Carrie Brodmerkel, Saurabh Mehandru, Mayte Suárez-Fariñas, El-ad David Amir, Seunghee Kim-Schulze, Bruce E. Sands, Jacqueline Perrigoue, Andrew Kasarskis, Carmen Argmann, Hao Ke
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 599-632 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background Inflammatory bowel disease (IBD) is a complex disease with variable presentation, progression, and response to therapies. Current disease classification is based on subjective clinical phenotypes. The peripheral blood immunophenome can ref
Autor:
Elisabeth M. Davis, Katherine F. Simpson, Brian Claggett, Jacqueline Perrigoue, Eric U. Yee, Xueyan Guo, Felicia D. Allard, Ilyssa O. Gordon, Mark T. Osterman, Matthew A. Ciorba, Kelli L. VanDussen, Thaddeus S. Stappenbeck, Bincy Abraham, Julia J. Liu, Bo Shen, Sarah C. Glover, Katherine Li
Publikováno v:
Inflamm Bowel Dis
Background Therapeutic efficacy of biologics has remained at about 50% for 2 decades. In Crohn’s disease (CD) patients, we examined the predictive value of an epithelial cell biomarker, ileal microvillar length (MVL), for clinical response to ustek
Autor:
Carmen Argmann, Ruixue Hou, Ryan C Ungaro, Haritz Irizar, Zainab Al-Taie, Ruiqi Huang, Roman Kosoy, Swati Venkat, Won-Min Song, Antonio F Di'Narzo, Bojan Losic, Ke Hao, Lauren Peters, Phillip H Comella, Gabrielle Wei, Ashish Atreja, Milind Mahajan, Alina Iuga, Prerak T Desai, Patrick Branigan, Aleksandar Stojmirovic, Jacqueline Perrigoue, Carrie Brodmerkel, Mark Curran, Joshua R Friedman, Amy Hart, Esi Lamousé-Smith, Jan Wehkamp, Saurabh Mehandru, Eric E Schadt, Bruce E Sands, Marla C Dubinsky, Jean-Frederic Colombel, Andrew Kasarskis, Mayte Suárez-Fariñas
Publikováno v:
Gut. :gutjnl-2021
ObjectiveIBD therapies and treatments are evolving to deeper levels of remission. Molecular measures of disease may augment current endpoints including the potential for less invasive assessments.DesignTranscriptome analysis on 712 endoscopically def
Autor:
Shawn P. Fahl, Robert Sertori, Yong Zhang, Alejandra V. Contreras, Bryan Harris, Minshi Wang, Jacqueline Perrigoue, Siddharth Balachandran, Brian K. Kennedy, David L. Wiest
Publikováno v:
J Immunol
Ribosomal proteins are thought to primarily facilitate biogenesis of the ribosome and its ability to synthesize protein. However, in this study, we show that Rpl22-like1 (Rpl22l1) regulates hematopoiesis without affecting ribosome biogenesis or bulk
Autor:
Jacqueline Perrigoue, Luciana R. Muniz-Bongers, Luvena L. Ong, Yanqing Chen, Leon Chang, Karen Ngo, Aleksandar Stojmirovic, Christopher D. O’Brien, Matthew Germinaro, Rajesh Rao, Marion Vetter, Jennifer Towne
Publikováno v:
Gastroenterology. 162:S-794
Autor:
Jennifer E. Towne, Toru Nakata, Ariel Lefkovith, Chih Hung Chou, Ramnik J. Xavier, Aviv Regev, Lingfei Wang, Daniel B. Graham, Kai Liu, Junmei Yao, Alok Jaiswal, Kwontae You, Jacqueline Perrigoue, Abdifatah S. Omar
Publikováno v:
Science
Transcriptional control of proteostasis Tissue homeostasis requires the coordinated activity of multiple cell types to initiate and then resolve inflammation. Intrinsic cellular stress-response pathways facilitate adaptation to stress and tissue rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91fbf3e3013e227bf82e52d8669a9f4
https://europepmc.org/articles/PMC8315080/
https://europepmc.org/articles/PMC8315080/
Autor:
Joshua R. Friedman, Ruixue Hou, Antonio Fabio Di Narzo, Ruiqi Huang, Marla Dubinsky, Mayte Suárez-Fariñas, Eduard Rogatsky, Carmen Argmann, Tetyana Dodatko, Bruce E. Sands, Ryan C. Ungaro, Frédéric M. Vaz, Mark Curran, Carrie Brodmerkel, Jacqueline Perrigoue, Ke Hao, Roman Kosoy, Phillip H. Comella, Wenhui Wang, Manasi Agrawal, Amy B. Hart, Aleksandar Stojmirović, Jean-Frederic Colombel, Andrew Kasarskis, Gabrielle Wei, Sander M. Houten, Jun Zhu, Judy H. Cho, Eric E. Schadt
Publikováno v:
Gastroenterology
Polygenic and environmental factors are underlying causes of inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci controlling a metabolite's abundance, with known IBD genetic susceptibility loci, may help resolve met
Autor:
Maria Suprun, Anais Levescot, Marla Dubinsky, Lauren A. Peters, Judy H. Cho, Carrie Brodmerkel, Bruce E. Sands, Saurabh Mehandru, Lishomwa C. Ndhlovu, Joshua R. Friedman, Ruiqi Huang, Eric E. Schadt, Bojan Losic, Carmen Argmann, Antonio Di’Narzo, Ke Hao, Ryan C. Ungaro, Divya Jha, Gabrielle Wei, Jean-Frederic Colombel, Mark Curran, Sander M. Houten, Sascha Cording, Alexandra E. Livanos, Aleksandar Stojmirović, Roman Kosoy, Huaibin M. Ko, Minami Tokuyama, Michael J. Corley, Wenhui Wang, Andrew Kasarskis, Jun Zhu, Gustavo Martinez-Delgado, Jacqueline Perrigoue, Mayte Suárez-Fariñas, Nadine Cerf-Bensusan, Haritz Irizar, Noam Harpaz
Publikováno v:
Gastroenterology
Background and Aims The presence of gastrointestinal symptoms and high levels of viral RNA in the stool suggest active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication within enterocytes. Methods Here, in multiple, large cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290399b29148076f39dc00ebc0546f56
https://doi.org/10.1101/2020.05.21.109124
https://doi.org/10.1101/2020.05.21.109124
Autor:
Yongzhong Zhao, Mark E. Curran, Hardik Shah, Mary Beth Humphrey, Jeremiah J. Faith, Eunjee Lee, Arthur Mortha, Lauren A. Peters, Bojan Losic, Anuk Das, Brian A. Kidd, Eric M. Neiman, Sean R. Llewellyn, Radu Dobrin, Panos Roussos, Riccardo Miotto, Teresa K. Tarrant, Joshua R. Friedman, Antonio Fabio Di Narzo, Khader Shameer, Won-Min Song, Jun Zhu, Bin Zhang, Carmen Argmann, Eric E. Schadt, Alina Iuga, Carrie Brodmerkel, Jacqueline Perrigoue, Lloyd Mayer, Andrew Kasarskis, Yoshinori Fukui, Aleksandar Stojmirović, Jocelyn Sendecki, Brian M. Iritani, Shannon Telesco, Minghui Wang, Nicholas E.S. Sibinga, Ke Hao
Publikováno v:
Nature genetics
A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data sets to construct predictive models of IBD. We present a predictive model of the immune component of IBD that informs causal relationships among loci previou