Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jacqueline O. Gonatas"'
Publikováno v:
Journal of the Neurological Sciences. 246:21-30
Fragmentation of the neuronal Golgi apparatus (GA) was reported in amyotrophic lateral sclerosis (ALS), corticobasal degeneration, Alzheimer's and Creutzfeldt-Jacob disease, and in spinocerebelar ataxia type 2 (SCA2). In transgenic mice expressing th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b3f9eb70a731622d42e4f05cc072ea
https://doi.org/10.1016/j.jns.2006.01.019
https://doi.org/10.1016/j.jns.2006.01.019
Autor:
Daniel S. Spellman, Nicholas K. Gonatas, Christoph W. Strey, Xiaosong Wang, John D. Lambris, Anna Stieber, Jacqueline O. Gonatas
Publikováno v:
The American Journal of Pathology. 165:1701-1718
Gain-of-function mutations of the Cu/Zn superoxide dismutase (SOD1) gene cause dominantly inherited familial amyotrophic lateral sclerosis. The identification of differentially regulated proteins in spinal cords of paralyzed mice expressing SOD1(G93A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0715d97c013695ab9df5277aa1c253
https://doi.org/10.1016/s0002-9440(10)63426-8
https://doi.org/10.1016/s0002-9440(10)63426-8
Publikováno v:
Journal of the Neurological Sciences. 177:114-123
Mice expressing the G93A and other mutations of Cu,Zn superoxide dismutase (SOD1G93A) are valid models for the familial form of amyotrophic lateral sclerosis (FALS) with SOD1 mutations and, probably, for sporadic ALS. Adult mice become progressively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02b1135e8ab66061e1b7fb066f6d5e3
https://doi.org/10.1016/s0022-510x(00)00351-8
https://doi.org/10.1016/s0022-510x(00)00351-8
Autor:
Shuang Wei, Zissimos Mourelatos, Nicholas K. Gonatas, Koichi Okamoto, Anna Stieber, Youjun Chen, Jacqueline O. Gonatas
Publikováno v:
Acta Neuropathologica. 95:245-253
The Golgi apparatus (GA) of spinal cord motor neurons is fragmented in sporadic amyotrophic lateral sclerosis (ALS), and in asymptomatic and symptomatic transgenic mice expressing the G93A mutation of the gene of the human Cu,Zn superoxide dismutase,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897659db8460e4a3cffe433cd48e6323
https://doi.org/10.1007/s004010050794
https://doi.org/10.1007/s004010050794
Publikováno v:
Journal of Cell Science. 111:249-260
MG160, a type I cysteine-rich membrane sialoglycoprotein residing in the medial cisternae of the rat Golgi apparatus, is highly homologous to CFR, a fibroblast growth factor receptor, and ESL-1, an E-selectin ligand located at the cell surface of mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245b1bc7aa6f1553f44b6a461755fe44
https://doi.org/10.1242/jcs.111.2.249
https://doi.org/10.1242/jcs.111.2.249
Publikováno v:
Journal of Immunological Methods. 150:185-191
Over the last 20 years specific membrane polypeptides, such as receptors, enzymes, and organelle-specific antigens, have been visualized in the electron microscope with 'pre-embedding' or 'postembedding' methods of tissue processing (Anderson et al.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4ffb8b2825c25f5c550194d2318f44
https://doi.org/10.1016/0022-1759(92)90077-7
https://doi.org/10.1016/0022-1759(92)90077-7
Autor:
Spyros G.E. Mezitis, Nicholas K. Gonatas, Anna Stieber, B. Goud, Jacqueline O. Gonatas, S. E. Croul, Youjun Chen
Publikováno v:
Journal of Histochemistry & Cytochemistry. 38:957-963
We used a monoclonal antibody (10A8), derived from mice immunized with fractions enriched in Golgi apparatus of rat brain neurons, to isolate an intrinsic membrane sialoglycoprotein of 160 KD from rat brain. By immunoelectron microscopy the sialoglyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c773f09e69fa80521a1ac2ebf78f7f82
https://doi.org/10.1177/38.7.2355176
https://doi.org/10.1177/38.7.2355176
Autor:
H.-S. Yim, Jonni S. Moore, Nicholas K. Gonatas, M.B. Yim, Andrew Bantly, Anna Stieber, Jacqueline O. Gonatas
Publikováno v:
Journal of the neurological sciences. 219(1-2)
The Golgi apparatus of motor neurons (GA) is fragmented in sporadic amyotrophic lateral sclerosis (ALS), in familial ALS with SOD1 mutations, and in mice that express SOD1G93A of familial ALS, in which it was detected months before paralysis. In para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bf64158b8c15a3401a47f6291209a3
https://pubmed.ncbi.nlm.nih.gov/15050437
https://pubmed.ncbi.nlm.nih.gov/15050437
Publikováno v:
Journal of the neurological sciences. 173(1)
Transgenic mice that express the G93A mutation of human Cu,Zn superoxide dismutase (SOD1 G93A ), found in familial amyotrophic lateral sclerosis (FALS), showed clinical symptoms and histopathological changes of sporadic ALS, including fragmentation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a600f357d75fe41f4e237057f9b459f2
https://pubmed.ncbi.nlm.nih.gov/10675580
https://pubmed.ncbi.nlm.nih.gov/10675580
Autor:
Anna Stieber, Jacqueline O. Gonatas, Jean-Pierre Julien, Nicholas K. Gonatas, Peter Schweitzer, Jurgen Meier, Jean-Francois Collard
Publikováno v:
Journal of the neurological sciences. 173(1)
Fragmentation of the Golgi apparatus (GA) of motor neurons was first described in sporadic amyotrophic lateral sclerosis (ALS) and later confirmed in transgenic mice expressing the G93A mutation of the gene encoding the enzyme Cu,Zn superoxide dismut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc62170608f09b8a1bc51f81c1d2a71
https://pubmed.ncbi.nlm.nih.gov/10675581
https://pubmed.ncbi.nlm.nih.gov/10675581