Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jacqueline Norris"'
Autor:
Yi An, Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline Norris-Drouin, P. Brian Hardy, Tina M. Leisner, Kenneth H. Pearce, Dmitri Kireev
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Chemical probes are an indispensable tool for translating biological discoveries into new therapies, though are increasingly difficult to identify since novel therapeutic targets are often hard-to-drug proteins. We introduce FRASE-based hit-
Externí odkaz:
https://doaj.org/article/92dfd03cf5114759b14fbfa0d6d42945
Autor:
Carola Venturini, Bethany Bowring, Sally R. Partridge, Nouri L. Ben Zakour, Alicia Fajardo-Lubian, Ariana Lopez Ayala, Jilong Qin, Makrina Totsika, Gaby van Galen, Jacqueline Norris, Jonathan Iredell
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT The global epidemiology of multidrug resistant Klebsiella pneumoniae, a serious threat to both animal and human health, is dominated by the spread of pathogenic clones, each separately evolving via acquisition of transferable antibiotic resi
Externí odkaz:
https://doaj.org/article/e5ca775725a04b35af5f4367ef588f6b
Autor:
Mark Westman, Dennis Yang, Jennifer Green, Jacqueline Norris, Richard Malik, Yasmin A. Parr, Mike McDonald, Margaret J. Hosie, Sue VandeWoude, Craig Miller
Publikováno v:
Viruses, Vol 13, Iss 3, p 470 (2021)
Although the antibody response induced by primary vaccination with Fel-O-Vax® FIV (three doses, 2–4 weeks apart) is well described, the antibody response induced by annual vaccination with Fel-O-Vax® FIV (single dose every 12 months after primary
Externí odkaz:
https://doaj.org/article/337b8300c6a44528961a712f62ec36d8
Autor:
Mark Westman, Jacqueline Norris, Richard Malik, Regina Hofmann-Lehmann, Yasmin A. Parr, Emma Armstrong, Mike McDonald, Evelyn Hall, Paul Sheehy, Margaret J. Hosie
Publikováno v:
Viruses, Vol 13, Iss 2, p 240 (2021)
A field study undertaken in Australia compared the antibody responses induced in client-owned cats that had been vaccinated using two inactivated whole feline leukaemia virus (FeLV) vaccines, the monovalent vaccine Fel-O-Vax® Lv-K and the polyvalent
Externí odkaz:
https://doaj.org/article/a27afaffa44f423ca59dd2e91d562501
Autor:
Mark Westman, Jacqueline Norris, Richard Malik, Regina Hofmann-Lehmann, Andrea Harvey, Alicia McLuckie, Martine Perkins, Donna Schofield, Alan Marcus, Mike McDonald, Michael Ward, Evelyn Hall, Paul Sheehy, Margaret Hosie
Publikováno v:
Viruses, Vol 11, Iss 6, p 503 (2019)
A field study was undertaken to (i) measure the prevalence of feline leukaemia virus (FeLV) exposure and FeLV infection in a cross-section of healthy Australian pet cats; and (ii) investigate the outcomes following natural FeLV exposure in two Austra
Externí odkaz:
https://doaj.org/article/a12a8d19f4db4dd69455d7e7d8e76199
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32741 (2012)
Secretory human prostatic acid phosphatase (hPAP) is glycosylated at three asparagine residues (N62, N188, N301) and has potent antinociceptive effects when administered to mice. Currently, it is unknown if these N-linked residues are required for hP
Externí odkaz:
https://doaj.org/article/b3cd5679cf034be1b476611ecba8c93e
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 164KB, Jurkat and 697 cell cultures were treated with UNC569 (500 nM) for 1 hour. Pervanadate was added to cell cultures for 3 minutes to stabilize the phosphorylated form of Mer. Cells were harvested after 24 and after 48 hours. Mer was immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b792aace27e76d7bcaa5f15a741f4e
https://doi.org/10.1158/1535-7163.22498869.v1
https://doi.org/10.1158/1535-7163.22498869.v1
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 172KB, Jurkat cell cultures were treated with the indicated concentrations of UNC569 for 1 hour. Pervanadate was added to cell cultures for 3 minutes to stabilize the phosphorylated form of Tyro3. Tyro3 was immunoprecipitated from cell lysates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fd6e6b0eb551d5ec5540b41a540d51
https://doi.org/10.1158/1535-7163.22498872.v1
https://doi.org/10.1158/1535-7163.22498872.v1
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 294KB, TAM receptor expression in Jurkat cell line was detected by western blot analysis. Whole cell lysates were prepared and phosphorylated (denoted by p-) and total proteins were detected. Western blots representative of three independent ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaa550c21b0e6ea25a3b97df14e5550
https://doi.org/10.1158/1535-7163.22498875
https://doi.org/10.1158/1535-7163.22498875
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 634KB, Eighteen fish (Myc1-Myc18) were treated with UNC569 for 2 weeks. Animals were imaged pre- and post-treatment, with GFP intensities quantified as described in the text. Ten of 18 fish (55.6%; Myc1-Myc8, Myc10, Myc16) showed >50% regressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff6aa50828c6ca22386951e59806f8d
https://doi.org/10.1158/1535-7163.22498863
https://doi.org/10.1158/1535-7163.22498863