Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jacqueline Naylor"'
Autor:
Jo E. Lewis, Danae Nuzzaci, Paula-Peace James-Okoro, Mireia Montaner, Elisabeth O'Flaherty, Tamana Darwish, Marito Hayashi, Stephen D. Liberles, David Hornigold, Jacqueline Naylor, David Baker, Fiona M. Gribble, Frank Reimann
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101945- (2024)
Objective: Glucose dependent insulinotropic polypeptide (GIP) is well established as an incretin hormone, boosting glucose-dependent insulin secretion. However, whilst anorectic actions of its sister-incretin glucagon-like peptide-1 (GLP-1) are well
Externí odkaz:
https://doaj.org/article/f4e357a2899c4a37a4ab6ce977e8d82c
Autor:
Alessandro Boianelli, Pär Nordell, Joseph Earl, Jacqueline Naylor, David Hornigold, Rasmus Jansson Löfmark, Monika Sundqvist
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1310 (2024)
Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) play an important role in the treatment of type 2 diabetes (T2D) and obesity. The relationship between efficacy and dosing regimen has been studied extensively for this class of molecul
Externí odkaz:
https://doaj.org/article/bc3368e2f4524eb2b6cacea2fc7c70c5
Autor:
Myriam M. Ouberai, Ana L. Gomes Dos Santos, Sonja Kinna, David C. Hornigold, David Baker, Jacqueline Naylor, Lihuan Liang, Dominic J. Corkill, Mark E. Welland
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionOxyntomodulin (Oxm) hormone peptide has a number of beneficial effects on nutrition and metabolism including increased energy expenditure and reduced body weight gain. Despite its many advantages as a potential therapeutic agent, Oxm is s
Externí odkaz:
https://doaj.org/article/962b1f34d2a2490aa23517d91152667d
Autor:
Lichun Cai, Jeffrey Adelberg, Jacqueline Naylor-Adelberg, Guido Schnabel, Alejandro Calle, Zhigang Li, Gregory Reighard, Ksenija Gasic, Christopher A. Saski
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Armillaria root rot (ARR) poses a significant threat to the long-term productivity of stone-fruit and nut crops in the predominant production area of the United States. To mitigate this issue, the development of ARR-resistant and horticulturally-acce
Externí odkaz:
https://doaj.org/article/d5c15541431d4f00b6d9caf65e954d8e
Autor:
Sergei Pechenov, Jefferson Revell, Sarah Will, Jacqueline Naylor, Puneet Tyagi, Chandresh Patel, Lihuan Liang, Leo Tseng, Yue Huang, Anton I. Rosenbaum, Kemal Balic, Anish Konkar, Joseph Grimsby, J. Anand Subramony
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Peptide therapeutics are increasingly used in the treatment of disease, but their administration by injection reduces patient compliance and convenience, especially for chronic diseases. Thus, oral administration of a peptide therapeutic rep
Externí odkaz:
https://doaj.org/article/3ba0d823dad649b18d617f5537b9b8f7
Autor:
Berit Svendsen, Megan E. Capozzi, Jingjing Nui, Sarah A. Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A. D'Alessio, Jonathan E. Campbell
Publikováno v:
Molecular Metabolism, Vol 32, Iss , Pp 44-55 (2020)
Objective: Glucose-dependent insulinotropic polypeptide is an intestinally derived hormone that is essential for normal metabolic regulation. Loss of the GIP receptor (GIPR) through genetic elimination or pharmacological antagonism reduces body weigh
Externí odkaz:
https://doaj.org/article/df3bbfc71fd745cb979879e7636f9ff4
Autor:
Brandon B. Boland, Rhianna C. Laker, Siobhan O'Brien, Sadichha Sitaula, Isabelle Sermadiras, Jens Christian Nielsen, Pernille Barkholt, Urmas Roostalu, Jacob Hecksher-Sørensen, Sara Rubek Sejthen, Ditte Dencker Thorbek, Arthur Suckow, Nicole Burmeister, Stephanie Oldham, Sarah Will, Victor G. Howard, Benji M. Gill, Philip Newton, Jacqueline Naylor, David C. Hornigold, Jotham Austin, Louise Lantier, Owen P. McGuinness, James L. Trevaskis, Joseph S. Grimsby, Christopher J. Rhodes
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101392- (2022)
Objective: Obesity-linked type 2 diabetes (T2D) is a worldwide health concern and many novel approaches are being considered for its treatment and subsequent prevention of serious comorbidities. Co-administration of glucagon like peptide 1 (GLP-1) an
Externí odkaz:
https://doaj.org/article/b325ef86371a42baa07ae1549ba9e3b0
Autor:
Myriam M. Ouberai, Ana L. Gomes Dos Santos, Sonja Kinna, Shimona Madalli, David C. Hornigold, David Baker, Jacqueline Naylor, Laura Sheldrake, Dominic J. Corkill, John Hood, Paolo Vicini, Shahid Uddin, Steven Bishop, Paul G. Varley, Mark E. Welland
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The clinical potential of peptide therapeutic agents can only be fully realised once their physicochemical and pharmacokinetic properties are precisely controlled. Here the authors show a reversible peptide self-assembly strategy to control and prolo
Externí odkaz:
https://doaj.org/article/c7f770bfea9c44cf8e0311310d874e5d
Autor:
Guido Schnabel, Sarah B Miller, Christopher A. Saski, Stephen Parris, Jacqueline Naylor-Adelberg, Patricia K. Bryson, Ksenija Gasic, Gregory L. Reighard, Jeffrey Adelberg
Publikováno v:
In Vitro Cellular & Developmental Biology - Plant. 57:387-397
Armillaria and Desarmillaria spp. are causal agents of a devastating root-borne disease of peach. Breeding resistant rootstock requires a reliable screening tool. An in vitro co-culture screen designed for almond was modified by replacing agar-gelled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989fdfdf2747e6063a2fd45f58a797a5
https://doi.org/10.1007/s11627-020-10136-2
https://doi.org/10.1007/s11627-020-10136-2
Autor:
Yue Huang, Sergei Pechenov, Leo Tseng, Lihuan Liang, J. Anand Subramony, Joseph Grimsby, Sarah Will, Anish Konkar, Jacqueline Naylor, Chandresh Patel, Anton I. Rosenbaum, Kemal Balic, Jefferson D. Revell, Puneet Tyagi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Peptide therapeutics are increasingly used in the treatment of disease, but their administration by injection reduces patient compliance and convenience, especially for chronic diseases. Thus, oral administration of a peptide therapeutic represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a663eba5e4442c71ffdf0db819da5fe5
https://pubmed.ncbi.nlm.nih.gov/34795324
https://pubmed.ncbi.nlm.nih.gov/34795324