765 G>C POLYMORPHISM OF THE COX-2 GENE AND GASTRIC CANCER RISK IN BRAZILIAN POPULATION

Autor: Vanessa Maria de Lima Pazine CAMPANHOLO, Aledson Vitor FELIPE, Jacqueline Miranda de LIMA, Célia Aparecida Marques PIMENTA, Rogéria Maria VENTURA, Nora Manoukian FORONES

Publikováno v: Arquivos de Gastroenterologia, Vol 51, Iss 2, Pp 79-83 (2014)

Context Genomic alterations play important roles in gastric cancer carcinogenesis. Cyclooxygenases (COX) are important enzymes in the maintenance of mucosal integrity and in pathological processes, mainly in inflammation and cancer. The -765G>C COX-2

Externí odkaz: https://doaj.org/article/0df16089cd37435fb791a79b6c024f4a

Estudo do polimorfismo genético no gene p53 (códon 72) em câncer colorretal Role of the genetic polymorphism of p53 (codon 72) gene in colorectal cancer

Autor: Jacqueline Miranda de Lima, Patrícia Valéria Pereira Serafim, Ismael Dale Cotrim Guerreiro da Silva, Nora Manoukian Forones

Publikováno v: Arquivos de Gastroenterologia, Vol 43, Iss 1, Pp 8-13 (2006)

RACIONAL: Polimorfismos genéticos são variações genéticas que podem ocorrer em seqüências codificadoras e não-codificadoras, levando a alterações qualitativas e/ou quantitativas das proteínas em questão. O p53 é o gene mais comumente alt

Externí odkaz: https://doaj.org/article/a46d1b4de9784b0998be266f5c22559f

Study of the polymorphisms of cyclooxygenase-2 (−765G>C) and 5-lipoxygenase (1708G>A) in patients with colorectal cancer

Autor: Flavia Roche Moreira Latini, Vanessa Pazine, Celia Aparecida Marques Pimenta, Tiago Donizetti Silva, Jacqueline Miranda de Lima, Nora Manoukian Forones, Aledson Vitor Felipe

Publikováno v: Oncology Letters

Colorectal cancer (CRC) is the fourth most common cause of cancer-related mortality worldwide. Genetic alterations have been associated with an increased risk of cancer and greater tumor aggressiveness. Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e63e961d7d0aa60282a84d8b932178
http://europepmc.org/articles/PMC3881951

Cyclin D1 A870G Polymorphism in Brazilian Colorectal Cancer Patients

Autor: Nora Manoukian Forones, Ismael Dale Cotrim Guerreiro da Silva, Jacqueline Miranda de Lima, Lessileia Gomes de Souza

Publikováno v: Journal of Gastrointestinal Cancer. 39:118-123

Cyclin D1 (CCND1) is a regulatory protein involved in the cell cycle. A common G to A polymorphism in the CCND1 gene is implicated on the splicing of the CCND1 transcript, and this protein may be associated to a deregulated cell proliferation. Correl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6bd8985ffb57ea229c67d8eb5157cf
https://doi.org/10.1007/s12029-009-9057-z

765 G>C POLYMORPHISM OF THE COX-2 GENE AND GASTRIC CANCER RISK IN BRAZILIAN POPULATION

Autor: Aledson Vitor Felipe, Celia Aparecida Marques Pimenta, Vanessa Maria de Lima Pazine Campanholo, Rogéria Maria Ventura, Nora Manoukian Forones, Jacqueline Miranda de Lima

Publikováno v: Arquivos de Gastroenterologia, Volume: 51, Issue: 2, Pages: 79-83, Published: JUN 2014
Arquivos de Gastroenterologia, Vol 51, Iss 2, Pp 79-83 (2014)
Arquivos de Gastroenterologia v.51 n.2 2014
Arquivos de gastroenterologia
Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia
instacron:IBEPEGE

ContextGenomic alterations play important roles in gastric cancer carcinogenesis. Cyclooxygenases (COX) are important enzymes in the maintenance of mucosal integrity and in pathological processes, mainly in inflammation and cancer. The -765G>C COX-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7630de0247550986b22fb34e6bd4876b
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000200079&lng=en&tlng=en