Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jacqueline M. Nally"'
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 235-243 (2017)
Severed CNS axons often retract or dieback away from the injury site and fail to regenerate. The precise mechanisms underlying acute axonal dieback and secondary axonal degeneration remain poorly understood. Here we investigate the role of Ca2+ store
Externí odkaz:
https://doaj.org/article/0c6d342c1e2c4795b1cfcb170e1d9b9a
Publikováno v:
Neuroscience Letters. 660:51-56
Ryanodine receptors (RyRs) are highly conductive intracellular Ca2+ release channels and are widely expressed in many tissues, including the central nervous system. RyRs have been implicated in intracellular Ca2+ overload which can drive secondary da
Publikováno v:
Neurobiology of Disease, Vol 106, Iss, Pp 235-243 (2017)
Severed CNS axons often retract or dieback away from the injury site and fail to regenerate. The precise mechanisms underlying acute axonal dieback and secondary axonal degeneration remain poorly understood. Here we investigate the role of Ca2+ store
Autor:
Nicolas Pelisch, Ben C. Orem, Jacqueline M. Nally, Nicole S. Stivers, Joshua Williams, David P. Stirling
Publikováno v:
Experimental Neurology. 294:1-11
Microglia/macrophage activation and recruitment following spinal cord injury (SCI) is associated with both detrimental and reparative functions. Stimulation of the innate immune receptor Toll-like receptor-2 (TLR2) has shown to be beneficial followin