Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jacqueline M. Bye"'
Autor:
Samuel Aparicio, Michael Schulzer, Tony Kouzarides, Bruce A.J. Ponder, Hilal Özdağ, Carlos Caldas, Francois Fuks, Suet-Feung Chin, Charles Theillet, Margarida Ruas, Torsten O. Nielsen, Lori Linger, Ashok R. Venkitaraman, Aidan J. Doherty, Blake Gilks, Elena Cattaneo, Ed Schuuring, Chris P. Ponting, Lindsay Brown, Jacqueline M. Bye, David G. Huntsman, Ekaterina S. Jordanova, Jonathon Milner, David Bentley, Stephen Chia, Forrest D. Hsu, Luke Hughes-Davies, Anthony P. Cahn, David S. Yu, Joseph Ragaz
Publikováno v:
Hughes-Davies, L, Huntsman, D, Ruas, M, Fuks, F, Bye, J, Chin, S F, Milner, J, Brown, L A, Hsu, F, Gilks, B, Nielsen, T, Schulzer, M, Chia, S, Ragaz, J, Cahn, A, Linger, L, Ozdag, H, Cattaneo, E, Jordanova, E S, Schuuring, E, Yu, D S, Venkitaraman, A, Ponder, B, Doherty, A, Aparicio, S, Bentley, D, Theillet, C, Ponting, C P, Caldas, C & Kouzarides, T 2003, ' EMSY Links the BRCA2 Pathway to Sporadic Breast and Ovarian Cancer ', Cell, vol. 115, no. 5, pp. 523-535 . https://doi.org/10.1016/S0092-8674(03)00930-9
Cell, 115(5), 523-535. CELL PRESS
Cell, 115(5), 523-535. Cell Press
Cell, 115(5), 523-535. CELL PRESS
Cell, 115(5), 523-535. Cell Press
The BRCA2 gene is mutated in familial breast and ovarian cancer, and its product is implicated in DNA repair and transcriptional regulation. Here we identify a protein, EMSY, which binds BRCA2 within a region (exon 3) deleted in cancer. EMSY is capab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0ab620dfcecd771d879628763c951c
https://ora.ox.ac.uk/objects/uuid:266f243b-93aa-47b4-bd4b-a7f7c4251c83
https://ora.ox.ac.uk/objects/uuid:266f243b-93aa-47b4-bd4b-a7f7c4251c83
Autor:
Sarah C. L. Knowles, Luc J. Smink, David Beare, Charlotte G. Cole, Ian Dunham, Jacqueline M. Bye, Melanie E. Goward, Elizabeth J. Huckle, John E. Collins
Publikováno v:
Genome Research. 13:27-36
We report a second-generation gene annotation of human chromosome 22. Using expressed sequence databases, comparative sequence analysis, and experimental verification, we have extended genes, fused previously fragmented structures, and identified new
Autor:
Barbara D. Gorick, James D. Marks, Nevin C. Hughes-Jones, Willem H. Ouwehand, Jacqueline M. Bye
Publikováno v:
British Journal of Haematology. 105:811-816
Antibodies to the D antigen of the Rh system use a restricted set of immunoglobulin V and J gene segments, especially VH DP50 and DP63, JH6, Vlambda DPL16 and Jlambda 2/3. These gene segments may confer a natural affinity on the antibodies for the D
Publikováno v:
Journal of General Virology. 77:2531-2539
Hepatitis C virus (HCV) is the aetiological agent responsible for most cases of non-A non-B hepatitis. Hepatitis C is a disease of clinical importance because of its high infection rate in blood donors and its persistence as chronic infections which
Autor:
James D. Marks, Jacqueline M. Bye, Greg Winter, D. Voak, Susan J. Thorpe, Willem H. Ouwehand, Barbara D. Gorick, R. Finnern, Nevin C. Hughes-Jones
Publikováno v:
Nature Biotechnology. 11:1145-1149
We have isolated human antibody fragments with binding specificities against the blood group antigens of the ABO and I blood group systems (B and HI), of the Rh system (D and E) and of the Kell system (Kpb), by selecting a phage-antibody library on h
Autor:
Magnus Malmqvist, John McCafferty, Klaus Holliger, M J Embleton, Barbara D. Gorick, Jacqueline M. Bye, M Baier, James D. Marks, Nevin C. Hughes-Jones, Andrew D. Griffiths
Publikováno v:
The EMBO Journal. 12:725-734
Recently we demonstrated that human antibody fragments with binding activities against foreign antigens can be isolated from repertoires of rearranged V-genes derived from the mRNA of peripheral blood lymphocytes (PBLs) from unimmunized humans. The h
Autor:
Nevin C. Hughes-Jones, Christine Carter, Barbara D. Gorick, Greg Winter, Sirirurg Songsivilai, Yungchang Cui, Jacqueline M. Bye, James D. Marks
Publikováno v:
Journal of Clinical Investigation. 90:2481-2490
To date, there has been no systematic study of the process of affinity maturation of human antibodies. We therefore sequenced the variable region genes (V genes) of 14 human monoclonal antibodies specific for the erythrocyte Rh(D) alloantigen and det
Autor:
Andrew D. Griffiths, Jacqueline M. Bye, Greg Winter, Magnus Malmqvist, James D. Marks, Tim Clackson
Publikováno v:
Nature Biotechnology. 10:779-783
Diverse antibody libraries can be displayed on the surface of filamentous bacteriophage, and selected by panning of the phage with antigen. This allows human antibodies to be made directly in vitro without prior immunization, thus mimicking the prima
Publikováno v:
European Journal of Immunology. 20:2661-2666
Universal oligonucleotide primers, designed for amplifying and sequencing genes encoding the rearranged human lambda immunoglobulin variable region, were validated by amplification of the lambda light chain genes from four human heterohybridoma cell
Autor:
Eduardo, Eyras, Alexandre, Reymond, Robert, Castelo, Jacqueline M, Bye, Francisco, Camara, Paul, Flicek, Elizabeth J, Huckle, Genis, Parra, David D, Shteynberg, Carine, Wyss, Jane, Rogers, Stylianos E, Antonarakis, Ewan, Birney, Roderic, Guigo, Michael R, Brent
Publikováno v:
BMC Bioinformatics, Vol. 6 (2005) P. 131
BMC Bioinformatics, Vol 6, Iss 1, p 131 (2005)
BMC Bioinformatics, vol. 6, pp. 131
Recercat. Dipósit de la Recerca de Catalunya
instname
BMC Bioinformatics
BMC Bioinformatics, Vol 6, Iss 1, p 131 (2005)
BMC Bioinformatics, vol. 6, pp. 131
Recercat. Dipósit de la Recerca de Catalunya
instname
BMC Bioinformatics
Background: Despite the continuous production of genome sequence for a number of organisms,/nreliable, comprehensive, and cost effective gene prediction remains problematic. This is particularly/ntrue for genomes for which there is not a large collec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::747400740de93463795a82b12411e118
http://hdl.handle.net/10230/13154
http://hdl.handle.net/10230/13154