Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jacqueline M. Burrows"'
Autor:
Athena Nguyen, Keng Yih Chew, Emma J. Grant, Sweera Rehan, Dhilshan Jayasinghe, Alan Riboldi-Tunnicliffe, Lea Lekieffre, Stephanie Gras, Katie E. Lineburg, Jyothy Raju, Rajiv Khanna, Pauline Crooks, Christian A. Lobos, Demetra S.M. Chatzileontiadou, Hannah Sloane, Michelle A Neller, Weisan Chen, Tong Zwm, Srividhya Swaminathan, H. Halim, Corey Smith, Jacqueline M. Burrows, Lloyd D'Orsogna, Archana Panikkar, Kirsty R. Short, C. Szeto
Publikováno v:
SSRN Electronic Journal.
Significant efforts are being made worldwide to understand the immune response to SARS-CoV-2, responsible for the COVID-19 pandemic, including the role of pre-existing T cell immunity. Understanding the mechanisms that promote cross-recognition by T
Autor:
Lea Lekieffre, Zhen Wei Marcus Tong, Michelle A Neller, Jacqueline M. Burrows, Keng Yih Chew, Alan Riboldi-Tunnicliffe, Dhilshan Jayasinghe, Archana Panikkar, Kirsty R. Short, Jyothy Raju, Christopher Szeto, Andrea T. Nguyen, Emma J. Grant, Demetra S.M. Chatzileontiadou, Hanim Halim, Stephanie Gras, Sweera Rehan, Weisan Chen, Lloyd D'Orsogna, Corey Smith, Rajiv Khanna, Hannah Sloane, Srividhya Swaminathan, Katie E. Lineburg, Pauline Crooks, Christian A. Lobos
Publikováno v:
Immunity
Efforts are being made worldwide to understand the immune response to SARS-CoV-2, the virus responsible for the COVID-19 pandemic, including the impact of T cell immunity and cross-recognition with seasonal coronaviruses. Screening SARS-CoV-2 peptide
Autor:
Vivian S. W. Li, Andrea Schuessler, Leone Beagley, David D. Smith, Dora Lai Wan Kwong, Sandro V. Porceddu, David Price, Randal Tiu, Katherine K. Matthews, Glen M. Boyle, Janice Tsang, Emma Gostick, Daniel Chua, Sweera Rehan, John M. Nicholls, Jacqueline M. Burrows, Victor C. S. Lee, Michelle A Neller, Rajiv Khanna, Benedict Panizza, Corey Smith
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
Oncoimmunology
Oncoimmunology
Adoptive T cell therapy has emerged as a powerful strategy to treat human cancers especially haematological malignancies. Extension of these therapies to solid cancers remains a significant challenge especially in the context of defining immunologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ede4101386a0c87520da2865b8a54c
http://hdl.handle.net/10722/239533
http://hdl.handle.net/10722/239533
Autor:
I van der Mei, Steve Simpson, Terence Dwyer, Anne-Louise Ponsonby, Leigh Blizzard, Janette Taylor, Jacqueline M. Burrows, Fotini Pittas, Scott R. Burrows, Bruce V. Taylor, Dominic E. Dwyer
Publikováno v:
Acta Neurologica Scandinavica. 130:328-337
BACKGROUND: Among the environmental factors associated with multiple sclerosis (MS) causation, some of the strongest associations are with Epstein-Barr virus (EBV), and to a lesser extent human herpesvirus 6 (HHV6). Associations with clinical course
Autor:
John J. Miles, Jamie Rossjohn, Stephanie Gras, Scott R. Burrows, Thomas Elliott, Michelle A Neller, Rebekah M Brennan, Jacqueline M. Burrows
Publikováno v:
British Journal of Haematology. 166:148-152
[Extract] T cells play a central role in immunity as both regulators and effectors of immune function, following recognition of antigenic peptides presented by human leucocyte antigens (HLA) via the αβ T cell receptor (TCR). As such, the genes that
Autor:
Nathan P. Croft, James McCluskey, John J. Miles, Scott R. Burrows, Rajiv Khanna, Stephanie Gras, Jamie Rossjohn, Andrew David Welland, Rebekah M Brennan, Lucy C. Sullivan, Jacqueline M. Burrows, Anthony W. Purcell, Andrew G. Brooks, Melissa J Rist, Alexander Theodossis, Michelle A Neller, Zhenjun Chen
Publikováno v:
The Journal of Immunology. 191:561-571
Class I HLAs generally present peptides of 8–10 aa in length, although it is unclear whether peptide length preferences are affected by HLA polymorphism. In this study, we investigated the CD8+ T cell response to the BZLF1 Ag of EBV, which includes
Publikováno v:
Journal of Virology. 87:697-700
High-throughput T cell receptor sequencing on sequentially banked blood samples from healthy individuals has shown that high-frequency clonotypes can remain relatively stable for up to 18 years, with minimal inflation, deflation, or turnover. These p
Autor:
David Williams, I. A. F. van der Mei, Keith Dear, Scott R. Burrows, Terence Dwyer, Robyn M. Lucas, Bruce V. Taylor, Trevor J. Kilpatrick, Patricia C. Valery, Alan Coulthard, Anthony J. McMichael, Jacqueline M. Burrows, Michael P. Pender, Dominic E. Dwyer, Meav-Lang J Lay, C. Chapman, Anne-Louise Ponsonby
Publikováno v:
Neurology. 77:371-379
Objectives: To assess risk of a first clinical diagnosis of CNS demyelination (FCD) in relation to measures of Epstein-Barr virus (EBV) infection within the context of other known risk factors. Methods: This was a multicenter incident case-control st
Autor:
Jacqueline M. Burrows, Robyn M. Lucas, David R. Williams, Patricia C. Valery, Trevor J. Kilpatrick, Bruce V. Taylor, Keith Dear, Terence Dwyer, Caron Chapman, Anne-Louise Ponsonby, Michael P. Pender, Anthony J. McMichael, Ingrid van der Mei, Alan Coulthard
Publikováno v:
Multiple Sclerosis Journal. 16:994-1000
Background: Previous work has shown high levels of anti-Epstein Barr Virus (EBV) antibodies in individuals with multiple sclerosis (MS).Objectives: To examine history of glandular fever, anti-EBV antibody profile and whole blood viral load at first c
Autor:
Scott R. Burrows, Yu Chih Liu, Stephanie Gras, James McCluskey, Jacqueline M. Burrows, Melissa J. Bell, Zhenjun Chen, Anthony W. Purcell, Jamie Rossjohn, Andrew G. Brooks, Michelle A Neller, Rebekah M Brennan, Lucy C. Sullivan, Lars Kjer-Nielsen, John J. Miles, Rajiv Khanna
Publikováno v:
The Journal of Experimental Medicine
In comparison to human leukocyte antigen (HLA) polymorphism, the impact of allelic sequence variation within T cell receptor (TCR) loci is much less understood. Particular TCR loci have been associated with autoimmunity, but the molecular basis for t