Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jacqueline M Ogier"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The stria vascularis (SV) is a highly vascularized tissue lining the lateral wall of the cochlea. The SV maintains cochlear fluid homeostasis, generating the endocochlear potential that is required for sound transduction. In addition, the SV acts as
Externí odkaz:
https://doaj.org/article/53e60a82c62047fcbc5cd8b0b11c339c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/c688a3ccd5d747e692408010075a97f6
Autor:
Jacqueline M Ogier, Marina R Carpinelli, Benedicta D Arhatari, R C Andrew Symons, Benjamin T Kile, Rachel A Burt
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97559 (2014)
CHARGE syndrome is a rare human disorder caused by mutations in the gene encoding chromodomain helicase DNA binding protein 7 (CHD7). Characteristics of CHARGE are varied and include developmental ear and hearing anomalies. Here we report a novel mou
Externí odkaz:
https://doaj.org/article/691b24bcc35f4517b1e9cb1c0a99c15f
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
p38 mitogen-activated protein kinases (P38α and β) and c-Jun N-terminal kinases (JNK1, 2, and 3) are key mediators of the cellular stress response. However, prolonged P38 and JNK signalling is associated with damaging inflammatory responses, reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2f9ed03ee86db2af1247defe3cceac
https://doi.org/10.1007/s00109-020-01878-y
https://doi.org/10.1007/s00109-020-01878-y
Autor:
Jacqueline M. Ogier, Yujing Gao, Eileen M. Dunne, Michael A. Wilson, Sarath C. Ranganathan, Gregory H. Tesch, David J. Nikolic Paterson, Alain Dabdoub, Rachel A. Burt, Bryony A. Nayagam, Paul J. Lockhart
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 100(5)
Abstract Aminoglycoside antibiotics are lifesaving medicines, crucial for the treatment of chronic or drug resistant infections. However, aminoglycosides are toxic to the sensory hair cells in the inner ear. As a result, aminoglycoside-treated indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8253b7672074a65cb8309b647543c907
https://pubmed.ncbi.nlm.nih.gov/35536324
https://pubmed.ncbi.nlm.nih.gov/35536324
Autor:
Rachel A. Burt, E. Kim Mulholland, Catherine Satzke, Odilia L. C. Wijburg, Roy M. Robins-Browne, Jacqueline M. Ogier, John Pedersen, Richard Malley, Jayne Manning, Eileen M. Dunne, Nancy Wang
Publikováno v:
Vaccine. 37:3495-3504
The pneumococcus remains a common cause of otitis media (OM) despite the widespread introduction of pneumococcal conjugate vaccines. In mice, a pneumococcal whole cell vaccine (WCV) induces serotype-independent protection against pneumococcal colonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abe438c1759a7fa62b3a329e609c01b
https://doi.org/10.1016/j.vaccine.2019.03.013
https://doi.org/10.1016/j.vaccine.2019.03.013
Autor:
Jacqueline M. Ogier, Yujing Gao, Eileen M. Dunne, Michael A. Wilson, Sarath C. Ranganathan, Gregory H. Tesch, David J. Nikolic Paterson, Alain Dabdoub, Rachel A. Burt, Bryony A. Nayagam, Paul J. Lockhart
Publikováno v:
Journal of Molecular Medicine. 100:815-815
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a57fef48f531135a78a1f52b7fac4d80
https://doi.org/10.1007/s00109-022-02203-5
https://doi.org/10.1007/s00109-022-02203-5
Publikováno v:
Hearing research. 386
Many drugs on the World Health Organization's list of critical medicines are ototoxic, destroying sensory hair cells within the ear. These drugs preserve life, but patients can experience side effects including permanent hearing loss and vestibular d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f477cd52bcc3377bb4f5bbcc418590b
https://pubmed.ncbi.nlm.nih.gov/31864009
https://pubmed.ncbi.nlm.nih.gov/31864009
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The inner ear is a complex organ containing highly specialised cell types and structures that are critical for sensing sound and movement. In vivo, the inner ear is difficult to study due to the osseous nature of the otic capsule and its encapsulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89098352f7a8eaf589dbedcd09b5eb63
https://doi.org/10.3389/fncel.2019.00170
https://doi.org/10.3389/fncel.2019.00170
Autor:
Rachel A. Burt, Jacqueline M. Ogier, Marina R. Carpinelli, Bradley K. McColl, Benedicta D. Arhatari, Michael A. Wilson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Alternate splicing is a critical regulator of gene expression in eukaryotes, however genetic mutations can cause erroneous splicing and disease. Most recorded splicing disorders are caused by mutations of splice donor/acceptor sites, however intronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6832f29ce60169b0297994bf1d312c29
https://doi.org/10.1038/s41598-018-23856-8
https://doi.org/10.1038/s41598-018-23856-8