Výsledky vyhledávání - "Jacqueline London"

Akademický článek

Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome

Autor: Tomer Illouz, Arya Biragyn, Maria Florencia Iulita, Lisi Flores-Aguilar, Mara Dierssen, Ilario De Toma, Stylianos E. Antonarakis, Eugene Yu, Yann Herault, Marie-Claude Potier, Alexandra Botté, Randall Roper, Benjamin Sredni, Jacqueline London, William Mobley, Andre Strydom, Eitan Okun

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

The risk of severe outcomes following respiratory tract infections is significantly increased in individuals over 60 years, especially in those with chronic medical conditions, i.e., hypertension, diabetes, cardiovascular disease, dementia, chronic r

Externí odkaz: https://doaj.org/article/cdbe71e884d1479b9d8fdfcd805105d1

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Akademický článek

Sleep–wake architecture in mouse models for Down syndrome

Autor: Damien Colas, Jacqueline London, Abdallah Gharib, Raymond Cespuglio, Nicole Sarda

Publikováno v: Neurobiology of Disease, Vol 16, Iss 2, Pp 291-299 (2004)

Sleep–wake homeostasis is crucial for behavioral performances and memory both in the general population and in patients with learning disability, among whom were Down syndrome (DS) patients. We investigated, in mouse models of DS, cortical EEG and

Externí odkaz: https://doaj.org/article/febf06fe4e1141f68b767b090b7f5d33

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Akademický článek

Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression in Mice Causes Mitochondrial Vacuolization, Axonal Degeneration, and Premature Motoneuron Death and Accelerates Motoneuron Disease in Mice Expressing a Familial Amyotrophic Lateral Sclerosis Mutant SOD1

Autor: Dick Jaarsma, Elize D. Haasdijk, J.A.C. Grashorn, Richard Hawkins, Wim van Duijn, Hein W. Verspaget, Jacqueline London, Jan C. Holstege

Publikováno v: Neurobiology of Disease, Vol 7, Iss 6, Pp 623-643 (2000)

Cytosolic Cu/Zn superoxide dismutase (SOD1) is a ubiquitous small cytosolic metalloenzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide (H2O2). Mutations in the SOD1 gene cause a familial form of amyotrophic lateral sclerosis

Externí odkaz: https://doaj.org/article/db05d241e2cf4ff69c6dc01d193fb531

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When the Storm Comes

Autor: Hayes, Jacqueline London Elizabeth

This senior honors thesis, titled "When the Storm Comes," is a book of poems that details both the struggles and joys of growing up in a Southern community. Though there are many storms that exist throughout this work, the speaker finds ways to navig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::307ef1e4ca76a725e7e49f5f4130e32b

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Specific Susceptibility to COVID-19 in Adults with Down Syndrome

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
NeuroMolecular Medicine
NeuroMolecular Medicine, Humana Press, 2021, ⟨10.1007/s12017-021-08651-5⟩
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Neuromolecular Medicine
Neuromolecular medicine, Ahead of
NEUROMOLECULAR MEDICINE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Instituto de Salud Carlos III (ISCIII)
Recercat. Dipósit de la Recerca de Catalunya
instname

The current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for individuals with chronic medical conditions, in particular those with Down Syndrome (DS) who often exhibit a higher prevalence of respiratory tract infections, im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da42be179d8c886c96b677fc3a1ccd5b
https://ddd.uab.cat/record/237380

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Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain

Autor: Fabrice Daubigney, Jacqueline London, F K Ndiaye, Julien Dairou, Nathalie Janel, Linh-Chi Bui, Benoit Souchet, Christophe Magnan, Claude Rouch, Serge Luquet

Publikováno v: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2019, 56 (6), pp.3958-3971. ⟨10.1007/s12035-018-1323-2⟩

Cystathionine beta synthase (CBS) is one of the 225 genes on chromosome 21 (HSA 21) that are triplicated in persons with trisomy 21 (Down syndrome). Although most triplicate HSA21 genes have their orthologous genes on murine chromosome 16, the murine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd506af68fd2c61eac978cb932ef2041
https://pubmed.ncbi.nlm.nih.gov/30238388

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Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues

Autor: Julien Dairou, Jacqueline London, Benoit Souchet, Linh Chi Bui, Fabrice Daubigney, Christophe Magnan, Nathalie Janel, Serge Luquet, Jean-Maurice Delabar, Hind Medjaoui, Elodie Assayag, Claude Rouch

Publikováno v: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2018, 55, pp.3822-3831. ⟨10.1007/s12035-017-0591-6⟩

International audience; Trisomy 21 (T21) or Down syndrome (DS) is the most common genetic disorder associated with intellectual disability and affects around 5 million persons worldwide. Neuroanatomical phenotypes associated with T21 include slight r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3180c76ec84b333056e81dc85461e1d
https://hal-cnrs.archives-ouvertes.fr/hal-03105437

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Hydrological and biogeochemical controls governing the speciation and accumulation of selenium in a wetland influenced by mine drainage

Autor: Dirk Wallschläger, Nelson Belzile, Colin Fraser, Stephanie Simpson, Jacqueline London, Alan J. Martin, Yuwei Chen

Publikováno v: Environmental toxicology and chemistry. 37(7)

Controls governing the speciation and accumulation of Se in a 3.7-ha marsh influenced by mine drainage were assessed through examination of water balance, water quality, sediment, and plant tissue components. Over the 8-mo study period (April through

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2410e9fd337053435c11bfab9dc6304c
https://pubmed.ncbi.nlm.nih.gov/29480546

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Enhanced bioaccumulation and biotransformation of As in coral reef organisms surrounding a marine shallow-water hydrothermal vent system

Autor: Thomas Pichler, Jacqueline London, Roy E. Price, Maria Jose Ruiz-Chancho, Dirk Wallschläger

Publikováno v: Chemical Geology. 348:48-55

The marine shallow-water hydrothermal system in Tutum Bay, Ambitle Island, Papua New Guinea discharges as much as 1.5 kg of arsenic (As) per day into a coral reef ecosystem. Despite the amount of As released, coral reef organisms do not seem to be af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98c8986e20f5e099b6a08b24a19fccb2
https://doi.org/10.1016/j.chemgeo.2012.02.023

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