Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacqueline L. Egger"'
Autor:
Justin Watts, Mark D. Minden, Kimo Bachiashvili, Andrew M. Brunner, Sameem Abedin, Timothy Crossman, Magdalena Zajac, Veronica Moroz, Jacqueline L. Egger, Aarti Tarkar, Brandon E. Kremer, Olena Barbash, Gautam Borthakur
Publikováno v:
Therapeutic Advances in Hematology, Vol 15 (2024)
Background: GSK3326595 is a potent, selective, reversible protein arginine methyltransferase 5 (PRMT5) inhibitor under investigation for treatment of myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (
Externí odkaz:
https://doaj.org/article/41e271adc09543d4b1c4530ab475b544
Autor:
Lillian L. Siu, Thierry Horner, Anthony W. Tolcher, Kimberley M. Heinhuis, Drew W. Rasco, Arindam Dhar, Brandon E. Kremer, Shelby A. Gorman, Olena Barbash, Sophie Postel-Vinay, Jacqueline L. Egger
Publikováno v:
Cancer Research. 77:CT038-CT038
Background Protein arginine methyltransferase 5 (PRMT5) is the primary enzyme responsible for symmetric arginine dimethylation of multiple proteins that impact cell proliferation. Its substrates include histones and proteins involved in signal transd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a0a3ff66efac499237dc5b1a2f918f3
https://doi.org/10.1158/1538-7445.am2017-ct038
https://doi.org/10.1158/1538-7445.am2017-ct038