Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jacqueline L Bruce"'
Autor:
Drew F K Williamson, Sean R N Marris, Vanesa Rojas-Rudilla, Jacqueline L Bruce, Cloud P Paweletz, Geoffrey R Oxnard, Lynette M Sholl, Fei Dong
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264201 (2022)
Activating mutations in EGFR predict benefit from tyrosine kinase inhibitor therapy for patients with advanced non-small cell lung cancer. Directing patients to appropriate therapy depends on accurate and timely EGFR assessment in the molecular patho
Externí odkaz:
https://doaj.org/article/19219266db6d450e9c5a341aa6bcea1b
Autor:
Zhiru Li, Jacqueline L Bruce, Barry Cohen, Caileigh V Cunningham, William E Jack, Katell Kunin, Bradley W Langhorst, Jacob Miller, Reynes A Moncion, Catherine B Poole, Prem K Premsrirut, Guoping Ren, Richard J Roberts, Nathan A Tanner, Yinhua Zhang, Clotilde K S Carlow
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268692 (2022)
Effective management of the COVID-19 pandemic requires widespread and frequent testing of the population for SARS-CoV-2 infection. Saliva has emerged as an attractive alternative to nasopharyngeal samples for surveillance testing as it does not requi
Externí odkaz:
https://doaj.org/article/92026c356e18426da597bb818ba0347a
Autor:
Drew F. K. Williamson, Sean R. N. Marris, Vanesa Rojas-Rudilla, Jacqueline L. Bruce, Cloud P. Paweletz, Geoffrey R. Oxnard, Lynette M. Sholl, Fei Dong
Publikováno v:
PloS one. 17(2)
Activating mutations in EGFR predict benefit from tyrosine kinase inhibitor therapy for patients with advanced non-small cell lung cancer. Directing patients to appropriate therapy depends on accurate and timely EGFR assessment in the molecular patho
Autor:
Elizabeth P. Garcia, Priyanka Shivdasani, Frank C. Kuo, Vanesa Rojas-Rudilla, Amitabh Srivastava, Neal I. Lindeman, Shuji Ogino, Agoston T. Agoston, Matthew B. Yurgelun, Dimity Hall, Jonathan A. Nowak, Fei Dong, Jacqueline L. Bruce
Publikováno v:
The Journal of Molecular Diagnostics. 19:84-91
Mismatch repair protein deficiency (MMR-D) and high microsatellite instability (MSI-H) are features of Lynch syndrome–associated colorectal carcinomas and have implications in clinical management. We evaluate the ability of a targeted next-generati
Publikováno v:
Archives of Pathology & Laboratory Medicine. 138:626-635
Context Pulmonary large cell carcinoma (LCC) includes tumors not readily diagnosed as adenocarcinoma (ADC) or squamous cell carcinoma on morphologic grounds, without regard to immunophenotype, according to the World Health Organization (WHO). This am
Publikováno v:
The Journal of molecular diagnostics : JMD. 18(6)
The methylation status of the promoter of the O6-methylguanine DNA methyltransferase gene (MGMT) is an established prognostic and predictive biomarker of glioblastoma (GBM). At the Center for Advanced Molecular Diagnostics, MGMT testing is performed
Publikováno v:
Molecular Cell. 6:737-742
Analysis of tumor-derived mutations has led to the suggestion that p16 INK4a , cyclin D1, cdk4, and the retinoblastoma protein (pRB) are components of a regulatory pathway that is inactivated in most tumor cells. Cell cycle arrest induced by p16 INK4
Autor:
Yi-qun Wang, Mary Ann Stevenson, Stuart K. Calderwood, Rong Zhong, Yue Xie, Jacqueline L. Bruce, Changmin Chen
Publikováno v:
Cell stresschaperones. 4(1)
The heat shock transcription factor (HSF) genes encode proteins that bind to the heat shock elements (HSE) of stress-inducible genes. We have observed the induction of HSF1, the ubiquitous member of the HSF family from a latent cytoplasmic state to a
To maintain genome stability, cells with damaged DNA must arrest to allow repair of mutations before replication. Although several key components required to elicit this arrest have been discovered, much of the pathway remains elusive. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b6b5f8003488680f453f06bb08b5f3
https://europepmc.org/articles/PMC21745/
https://europepmc.org/articles/PMC21745/
Publikováno v:
The Cell Cycle ISBN: 9781461360278
The regulation of the division cycles of eukaryotic cells has been intensively investigated in recent years and appears to involve both changes in gene expression and posttranslational modification of preexisting proteins1–3. Cell-cycle dependent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f774e056b169d70a2abee859d149d8f6
https://doi.org/10.1007/978-1-4615-2421-2_17
https://doi.org/10.1007/978-1-4615-2421-2_17