Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jacqueline Keye"'
Autor:
Hao Wu, Yijie Han, Yasmina Rodriguez Sillke, Hongzhang Deng, Sophiya Siddiqui, Christoph Treese, Franziska Schmidt, Marie Friedrich, Jacqueline Keye, Jiajia Wan, Yue Qin, Anja A Kühl, Zhihai Qin, Britta Siegmund, Rainer Glauben
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 11, Pp 1-17 (2019)
Abstract Tumor‐associated macrophages (TAMs) promote tumor growth and metastasis by suppressing tumor immune surveillance. Herein, we provide evidence that the immunosuppressive phenotype of TAMs is controlled by long‐chain fatty acid metabolism,
Externí odkaz:
https://doaj.org/article/8c67af085da04323ba732ea32b84e9f4
Autor:
Hao Wu, Carl Weidinger, Franziska Schmidt, Jacqueline Keye, Marie Friedrich, Cansu Yerinde, Gerald Willimsky, Zhihai Qin, Britta Siegmund, Rainer Glauben
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Tumor infiltrating myeloid cells play contradictory roles in the tumor development. Dendritic cells and classical activated macrophages support anti-tumor immune activity via antigen presentation and induction of pro-inflammatory immune resp
Externí odkaz:
https://doaj.org/article/8191c67f68f7481b88466fe86aaca7ae
Autor:
Erik Brauer, Tobias Lange, Daniela Keller, Sophie Görlitz, Simone Cho, Jacqueline Keye, Manfred Gossen, Ansgar Petersen, Uwe Kornak
Publikováno v:
Brauer, E.; Lange, T.; Keller, D.; Görlitz, S.; Cho, S.; Keye, J.; Gossen, M.; Petersen, A.; Kornak, U.: Dissecting the influence of cellular senescence on cell mechanics and extracellular matrix formation in vitro. In: Aging Cell. Vol. 22 (2023) 3, e13744. (DOI: /10.1111/acel.13744)
Tissue formation and healing both require cell proliferation and migration, but also extracellular matrix production and tensioning. In addition to restricting proliferation of damaged cells, increasing evidence suggests that cellular senescence also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79251c562e9eae3cffbf3ee47a161d26
https://pubmed.ncbi.nlm.nih.gov/36514868
https://pubmed.ncbi.nlm.nih.gov/36514868
Autor:
Cansu Yerinde, Jacqueline Keye, Sibel Durlanik, Inka Freise, Franziska Nowak, Hsiang-Jung Hsiao, Marilena Letizia, Stephan Schlickeiser, Benedikt Obermayer, Adrian Huck, Marie Friedrich, Hao Wu, Désirée Kunkel, Anja A. Kühl, Sebastian Bauer, Andreas Thiel, Britta Siegmund, Rainer Glauben, Carl Weidinger
Class II histone deacetylases (HDAC) orchestrate T cell-dependent immune responses via the epigenetic control of genes and via the post-translational modification of cytoplasmic and nuclear proteins. However, the contribution of single HDAC family me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bedc0e758b891e7d7ceb3a234ad488bd
https://doi.org/10.1101/2022.09.18.508452
https://doi.org/10.1101/2022.09.18.508452
Autor:
Stephan Schlickeiser, Britta Siegmund, Hao Wu, Andreas Thiel, I Freise, Carl Weidinger, Désirée Kunkel, Marie Friedrich, Anja A. Kühl, Jacqueline Keye, Cansu Yerinde, S Durlanik, Rainer Glauben, Franziska Schmidt
Publikováno v:
Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65af1fe6e84c6cb3af9efdc1007efe23
https://doi.org/10.1055/s-0041-1733718
https://doi.org/10.1055/s-0041-1733718
Autor:
Marco Gerling, Rita Rosenthal, Britta Siegmund, Carl Weidinger, Hao Wu, Franziska Schmidt, Rainer Glauben, Marie Friedrich, Lorenz Gerbeth, Wilko Weichert, Katja Steiger, Jacqueline Keye
Publikováno v:
Mucosal Immunology. 12:656-667
Intact epithelial barrier function is pivotal for maintaining intestinal homeostasis. Current therapeutic developments aim at restoring the epithelial barrier in inflammatory bowel disease. Histone deacetylase (HDAC) inhibitors are known to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0ec4f491ca3245d2220f750a77ae8b
https://doi.org/10.1038/s41385-019-0135-7
https://doi.org/10.1038/s41385-019-0135-7
Autor:
Radoslav Chekerov, Jacqueline Keye, Jalid Sehouli, Nicolette Halben, Johanna Plendl, Sylvia Mechsner, Renata Voltolini Velho
Publikováno v:
Reproductive biomedicine online. 43(2)
Research question What is the potential role of immune cells and their inflammatory cytokines in the pathogenesis, development and establishment of endometriosis? Design Peritoneal fluid from 59 women (43 with endometriosis and 16 controls) who had u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894db4d5b4149e3c91e2e71e07114bcf
https://pubmed.ncbi.nlm.nih.gov/34103260
https://pubmed.ncbi.nlm.nih.gov/34103260
Publikováno v:
JCI Insight. 5
IL-4 is a pleiotropic antiinflammatory cytokine, which can be neuroprotective after nervous system injury. The beneficial actions of IL-4 are thought to result from the blunting of action of inflammatory mediators, such as proinflammatory cytokines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd490bc1dd923a1469b13ee386c94db1
https://doi.org/10.1172/jci.insight.133093
https://doi.org/10.1172/jci.insight.133093
Autor:
Hubert Hackl, Rainer Glauben, Katja Dahlke, Zlatko Trajanoski, Michael Blaut, Britta Siegmund, Christiane Ring, Michael Schumann, Anja A. Kühl, A. Batra, Jacqueline Keye, Gunnar Loh, Hao Wu, Franziska Schmidt, Marie Friedrich, Monika Schaubeck
Publikováno v:
Journal of Crohn's and Colitis
Background and Aims Contact with distinct microbiota early in life has been shown to educate the mucosal immune system, hence providing protection against immune-mediated diseases. However, the impact of early versus late colonization with regard to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c048ce1a859ec4a2f59a1637e41152d8
https://hdl.handle.net/21.11116/0000-0005-AF3A-621.11116/0000-0006-E4EF-C
https://hdl.handle.net/21.11116/0000-0005-AF3A-621.11116/0000-0006-E4EF-C
Autor:
Marie, Friedrich, Lorenz, Gerbeth, Marco, Gerling, Rita, Rosenthal, Katja, Steiger, Carl, Weidinger, Jacqueline, Keye, Hao, Wu, Franziska, Schmidt, Wilko, Weichert, Britta, Siegmund, Rainer, Glauben
Publikováno v:
Mucosal immunology. 12(3)
Intact epithelial barrier function is pivotal for maintaining intestinal homeostasis. Current therapeutic developments aim at restoring the epithelial barrier in inflammatory bowel disease. Histone deacetylase (HDAC) inhibitors are known to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e32036b2f3d3e22f545b5410b654f0b
https://pubmed.ncbi.nlm.nih.gov/30674988
https://pubmed.ncbi.nlm.nih.gov/30674988