Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jacqueline Kalb"'
Autor:
Gabriele Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert, Eoin Leen, Olga Sumara, Julia Hofstetter, Steffi Herold, Jacqueline Kalb, Apoorva Baluapuri, Evon Poon, Colin Kwok, Louis Chesler, Hans Michael Maric, David S. Rickman, Elmar Wolf, Richard Bayliss, Susanne Walz, Martin Eilers
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3483-3497 (2017)
Summary: MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma
Externí odkaz:
https://doaj.org/article/09207f0506bb47e089f8a4b47d59ee99
Autor:
Jacqueline Kalb, Guido Mastrobuoni, Nadine Royla, Andreas Schlosser, Stefan Kempa, Elmar Wolf, Susanne Walz, Francesca R Dejure, Carsten P. Ade, Martin Eilers, Jens T. Vanselow, Steffi Herold
Publikováno v:
The EMBO Journal. 36:1854-1868
Deregulated expression of MYC enhances glutamine utilization and renders cell survival dependent on glutamine, inducing "glutamine addiction". Surprisingly, colon cancer cells that express high levels of MYC due to WNT pathway mutations are not gluta
Autor:
Elmar Wolf, Martin Eilers, Jan Koster, Apoorva Baluapuri, Rogier Versteeg, Sabrina Rodewald, Daniel Solvie, Gabriele Büchel, Jacqueline Kalb, Carsten P. Ade, Jiajia Xu, Steffi Herold, Jan J. Molenaar, Anne Carstensen, Susanne Walz, Matthias Dobbelstein, Christina Klotz, Christina Schülein-Völk
Publikováno v:
Nature, 567(7749), 545-549. Nature Publishing Group
Nature
Nature
MYC is an oncogenic transcription factor that binds globally to active promoters and promotes transcriptional elongation by RNA polymerase II (RNAPII) 1,2 . Deregulated expression of the paralogous protein MYCN drives the development of neuronal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37bd98d02d532b4bdc8b99c953d2313
https://pure.amc.nl/en/publications/recruitment-of-brca1-limits-mycndriven-accumulation-of-stalled-rna-polymerase(d9d6a680-7598-45d0-9639-443cc9d59a22).html
https://pure.amc.nl/en/publications/recruitment-of-brca1-limits-mycndriven-accumulation-of-stalled-rna-polymerase(d9d6a680-7598-45d0-9639-443cc9d59a22).html
Autor:
Martin Eilers, Anne Carstensen, David S. Rickman, Richard Bayliss, Apoorva Baluapuri, Colin Kwok, Jacqueline Kalb, Hans Michael Maric, Steffi Herold, Elmar Wolf, Evon Poon, Ka-Yan Mak, Julia Hofstetter, Gabriele Büchel, Olga Sumara, Eoin Leen, Susanne Walz, Isabelle Roeschert, Louis Chesler
Publikováno v:
Büchel, G, Carstensen, A, Mak, K-Y, Roeschert, I, Leen, E, Sumara, O, Hofstetter, J, Herold, S, Kalb, J, Baluapuri, A, Poon, E, Kwok, C, Chesler, L, Maric, H M, Rickman, D S, Wolf, E, Bayliss, R, Walz, S & Eilers, M 2017, ' Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle ', Cell Reports, vol. 21, no. 12, pp. 3483-3497 . https://doi.org/10.1016/j.celrep.2017.11.090
Cell Reports, Vol 21, Iss 12, Pp 3483-3497 (2017)
Cell Reports
Cell Reports, Vol 21, Iss 12, Pp 3483-3497 (2017)
Cell Reports
Summary MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f725aa21a099d6cae3f22c67ec89042f
https://curis.ku.dk/portal/da/publications/association-with-auroraa-controls-nmycdependent-promoter-escape-and-pause-release-of-rna-polymerase-ii-during-the-cell-cycle(ae707ba4-4a1f-4865-95e6-a7888dfac817).html
https://curis.ku.dk/portal/da/publications/association-with-auroraa-controls-nmycdependent-promoter-escape-and-pause-release-of-rna-polymerase-ii-during-the-cell-cycle(ae707ba4-4a1f-4865-95e6-a7888dfac817).html