Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jacqueline K. Lekostaj"'
Autor:
Austin A. Larson, Peter R. Baker, Miroslav P. Milev, Craig A. Press, Ronald J. Sokol, Mary O. Cox, Jacqueline K. Lekostaj, Aaron A. Stence, Aaron D. Bossler, Jennifer M. Mueller, Keshika Prematilake, Thierry Fotsing Tadjo, Charles A. Williams, Michael Sacher, Steven A. Moore
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Transport protein particle (TRAPP) is a supramolecular protein complex that functions in localizing proteins to the Golgi compartment. The TRAPPC11 subunit has been implicated in muscle disease by virtue of homozygous and compound
Externí odkaz:
https://doaj.org/article/34eec2f6491f4e40885be0912b53e061
Autor:
Craig A. Press, Keshika Prematilake, Peter R. Baker, Charles A. Williams, Aaron D. Bossler, Thierry Fotsing Tadjo, Miroslav P. Milev, Ronald J. Sokol, Steven A. Moore, Jacqueline K. Lekostaj, Mary O. Cox, Jennifer Mueller, Aaron A. Stence, Austin Larson, Michael Sacher
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 8, Iss 1, Pp 1-10 (2018)
Skeletal Muscle, Vol 8, Iss 1, Pp 1-10 (2018)
Background Transport protein particle (TRAPP) is a supramolecular protein complex that functions in localizing proteins to the Golgi compartment. The TRAPPC11 subunit has been implicated in muscle disease by virtue of homozygous and compound heterozy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fefe017c97ca357ac88ba0861d6c233
https://doi.org/10.1186/s13395-018-0163-0
https://doi.org/10.1186/s13395-018-0163-0
Autor:
Jayakumar K. Natarajan, Jacqueline K. Lekostaj, Christian Wolf, Paul D. Roepe, Michelle F. Paguio
Publikováno v:
Biochemistry. 47:10394-10406
Several models describing how amino acid substitutions in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) confer resistance to chloroquine (CQ) and other antimalarial drugs have been proposed. Further progress requires molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c9a94a95984b225869ef7e94d207a2
https://doi.org/10.1021/bi8010658
https://doi.org/10.1021/bi8010658
Publikováno v:
Biochemistry. 46:6060-6073
Mutation of the P. falciparum chloroquine resistance transporter (PfCRT) causes resistance to chloroquine (CQ) and other antimalarial drugs. Mutation and/or overexpression of one of the multidrug resistance protein homologues found in this malarial p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a35addd4b4b478431b06cdc63d3eb8e
https://doi.org/10.1021/bi7002026
https://doi.org/10.1021/bi7002026
We utilize the recent successful overexpression of recombinant Plasmodium falciparum multi-drug resistance transporter, purification and reconstitution of the protein, and a novel high affinity chloroquine analogue to probe hypothesized interaction b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e01aef8334bee76cf42b24e235fa512
https://europepmc.org/articles/PMC2906614/
https://europepmc.org/articles/PMC2906614/
Publikováno v:
Molecular and biochemical parasitology. 157(1)
The mechanism behind how PfMDR1 may contribute to antimalarial drug resistance is unclear. Transfection studies suggest that PfMDR1 mutations may make small contributions to drug sensitivity in a strain-dependent fashion, whereas field data link over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02151d46510319fab34a8b1430a82482
https://pubmed.ncbi.nlm.nih.gov/18006157
https://pubmed.ncbi.nlm.nih.gov/18006157
Autor:
Jacqueline K. Lekostaj
This predoctoral training grant supported by the Department of Defense Breast Cancer Research Program (BCRP) of the Office of the Congressionally Directed Medical Research Programs (CDMRP) aims to study the possible role of ABC transporters in altere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46c1793c0397681ae7f51f30ad8c70f7
https://doi.org/10.21236/ada470298
https://doi.org/10.21236/ada470298
Publikováno v:
Blood. 122:4329-4329
Introduction Lymphoma is usually considered a monoclonal process that can be present at one or more anatomic sites in a patient. In the setting of combined Epstein Barr virus (EBV) infection and immunosuppression, clonally distinct lymphoproliferativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22a2d98a8c5dcad1809e474a84af381
https://doi.org/10.1182/blood.v122.21.4329.4329
https://doi.org/10.1182/blood.v122.21.4329.4329