Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Jacqueline K Phillips"'
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254554 (2021)
Chronic kidney disease (CKD) is a significant health challenge associated with high cardiovascular mortality risk. Historically, cardiovascular mortality risk has been found to higher in men than women in the general population. However, recent resea
Externí odkaz:
https://doaj.org/article/e7b5e040da284eca984c1743d185af5f
Autor:
Michelle H T Ta, Kristina G Schwensen, Sheryl Foster, Mayuresh Korgaonkar, Justyna E Ozimek-Kulik, Jacqueline K Phillips, Anthony Peduto, Gopala K Rangan
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164193 (2016)
The disease-modifying effects of target of rapamycin complex 1 (TORC1) inhibitors during different stages of polycystic kidney disease (PKD) are not well defined. In this study, male Lewis Polycystic Kidney Disease (LPK) rats (a genetic ortholog of h
Externí odkaz:
https://doaj.org/article/5cdcf556d3324a9ea0ff5ee7834e3cc9
Autor:
Kingsley C. Duru, Elena G. Kovaleva, Cara M. Hildreth, Alberto P. Avolio, Jacqueline K. Phillips, Mark Butlin
Publikováno v:
Journal of Functional Foods, Vol 114, Iss , Pp 106060- (2024)
Isoflavones have been identified as potential anti-diabetic agents, but adverse side effects especially at high dosage has continued to plague their clinical uptake. We explore the benefits of individual and co-treatment of diabetic rodents with isof
Externí odkaz:
https://doaj.org/article/07e1ba19e9834db78f09aecbd51491e9
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bd72aeacb50d40ec9615b80733eb17e8
Autor:
Conor F. Underwood, Peter G.R. Burke, Natasha N. Kumar, Ann K. Goodchild, Simon McMullan, Jacqueline K. Phillips, Cara M. Hildreth
Publikováno v:
Neuroendocrinology. 112:1200-1213
Introduction: Angiotensin (Ang) II signalling in the hypothalamic paraventricular nucleus (PVN) via Ang type-1a receptors (AT1R) regulates vasopressin release and sympathetic nerve activity – two effectors of blood pressure regulation. We determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f789687d1f6e43bf1b6f185acf9b2d0a
https://doi.org/10.1159/000525337
https://doi.org/10.1159/000525337
Autor:
Ananda Staats Pires, Shabarni Gupta, Sean A Barton, Roshana Vander Wall, Vanessa Tan, Benjamin Heng, Jacqueline K Phillips, Gilles J Guillemin
Publikováno v:
International journal of tryptophan research : IJTR. 15
Autosomal recessive polycystic kidney disease (ARPKD) is an early onset genetic disorder characterized by numerous renal cysts resulting in end stage renal disease. Our study aimed to determine if metabolic reprogramming and tryptophan (Trp) metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af8978a71f32b4a10302347291e99d8
https://pubmed.ncbi.nlm.nih.gov/36329761
https://pubmed.ncbi.nlm.nih.gov/36329761
Publikováno v:
Hypertension Journal. 6:142-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb3316e8c4b5dfc9454d284ce1cd523
https://doi.org/10.15713/ins.johtn.0200
https://doi.org/10.15713/ins.johtn.0200
Publikováno v:
Journal of Hypertension. 41:e364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd913abd8c441634f38e90e7ff6789fb
https://doi.org/10.1097/01.hjh.0000916504.25761.fd
https://doi.org/10.1097/01.hjh.0000916504.25761.fd
Publikováno v:
Genes, Vol 12, Iss 1762, p 1762 (2021)
Genes
Genes
The exponential rise in our understanding of the aetiology and pathophysiology of genetic cystic kidney diseases can be attributed to the identification of cystogenic genes over the last three decades. The foundation of this was laid by positional cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3d28e1dff732cacd2d7cd4e9126044
https://www.mdpi.com/2073-4425/12/11/1762
https://www.mdpi.com/2073-4425/12/11/1762
Autor:
Chai K. Lim, Ahmed A. Rahman, Jacqueline K. Phillips, Cara M. Hildreth, Paul M. Pilowsky, Sean A. Barton, Sheran Li, Benjamin F. Wyse
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
We examined the effect of total and afferent renal denervation (RDN) on hypertension and the renin-angiotensin system (RAS) in a rodent model of juvenile-onset polycystic kidney disease (PKD). Lewis Polycystic Kidney (LPK) and control rats received t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ee85ea09f6bc5bc32fe92f35a777ec
http://europepmc.org/articles/PMC8275789
http://europepmc.org/articles/PMC8275789