Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Jacqueline K Phillips"'
Autor:
Kingsley C. Duru, Elena G. Kovaleva, Cara M. Hildreth, Alberto P. Avolio, Jacqueline K. Phillips, Mark Butlin
Publikováno v:
Journal of Functional Foods, Vol 114, Iss , Pp 106060- (2024)
Isoflavones have been identified as potential anti-diabetic agents, but adverse side effects especially at high dosage has continued to plague their clinical uptake. We explore the benefits of individual and co-treatment of diabetic rodents with isof
Externí odkaz:
https://doaj.org/article/07e1ba19e9834db78f09aecbd51491e9
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bd72aeacb50d40ec9615b80733eb17e8
Autor:
Sheran Li, Cara M. Hildreth, Ahmed A. Rahman, Sean A. Barton, Benjamin F. Wyse, Chai K. Lim, Paul M. Pilowsky, Jacqueline K. Phillips
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract We examined the effect of total and afferent renal denervation (RDN) on hypertension and the renin-angiotensin system (RAS) in a rodent model of juvenile-onset polycystic kidney disease (PKD). Lewis Polycystic Kidney (LPK) and control rats r
Externí odkaz:
https://doaj.org/article/48a77c43345347dcab9d38e3bb3a6bbb
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Carotid body feedback and hypoxia may serve to enhance respiratory–sympathetic nerve coupling (respSNA) and act as a driver of increased blood pressure. Using the Lewis polycystic kidney (LPK) rat model of chronic kidney disease, we examined respSN
Externí odkaz:
https://doaj.org/article/0267202fed1d4149901976a79b387603
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254554 (2021)
Chronic kidney disease (CKD) is a significant health challenge associated with high cardiovascular mortality risk. Historically, cardiovascular mortality risk has been found to higher in men than women in the general population. However, recent resea
Externí odkaz:
https://doaj.org/article/e7b5e040da284eca984c1743d185af5f
Publikováno v:
Artery Research, Vol 26, Iss Supplement 1 (2020)
Purpose: Studies support beneficial effects of isoflavones, but antidiabetic effects of these agents remains unconfirmed [1,2]. This pilot study investigates isoflavones and Inonotus obliquus (chaga) extract effects on diabetes. Methods: Diabetes wa
Externí odkaz:
https://doaj.org/article/49e538c24f4245438584d0aceb912c09
Autor:
Conor F. Underwood, Peter G.R. Burke, Natasha N. Kumar, Ann K. Goodchild, Simon McMullan, Jacqueline K. Phillips, Cara M. Hildreth
Publikováno v:
Neuroendocrinology. 112:1200-1213
Introduction: Angiotensin (Ang) II signalling in the hypothalamic paraventricular nucleus (PVN) via Ang type-1a receptors (AT1R) regulates vasopressin release and sympathetic nerve activity – two effectors of blood pressure regulation. We determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f789687d1f6e43bf1b6f185acf9b2d0a
https://doi.org/10.1159/000525337
https://doi.org/10.1159/000525337
Autor:
Ananda Staats Pires, Shabarni Gupta, Sean A Barton, Roshana Vander Wall, Vanessa Tan, Benjamin Heng, Jacqueline K Phillips, Gilles J Guillemin
Publikováno v:
International journal of tryptophan research : IJTR. 15
Autosomal recessive polycystic kidney disease (ARPKD) is an early onset genetic disorder characterized by numerous renal cysts resulting in end stage renal disease. Our study aimed to determine if metabolic reprogramming and tryptophan (Trp) metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af8978a71f32b4a10302347291e99d8
https://pubmed.ncbi.nlm.nih.gov/36329761
https://pubmed.ncbi.nlm.nih.gov/36329761
Autor:
Michelle H T Ta, Kristina G Schwensen, Sheryl Foster, Mayuresh Korgaonkar, Justyna E Ozimek-Kulik, Jacqueline K Phillips, Anthony Peduto, Gopala K Rangan
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164193 (2016)
The disease-modifying effects of target of rapamycin complex 1 (TORC1) inhibitors during different stages of polycystic kidney disease (PKD) are not well defined. In this study, male Lewis Polycystic Kidney Disease (LPK) rats (a genetic ortholog of h
Externí odkaz:
https://doaj.org/article/5cdcf556d3324a9ea0ff5ee7834e3cc9
Publikováno v:
Hypertension Journal. 6:142-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb3316e8c4b5dfc9454d284ce1cd523
https://doi.org/10.15713/ins.johtn.0200
https://doi.org/10.15713/ins.johtn.0200