Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jacqueline Heger"'
Autor:
Jonas Knittel, Nadja Itani, Rolf Schreckenberg, Jacqueline Heger, Susanne Rohrbach, Rainer Schulz, Klaus-Dieter Schlüter
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 1013 (2023)
Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs). Receptor-dependent effects are specific for seroton
Externí odkaz:
https://doaj.org/article/f240e7988aa94e02894008905ab7a2ea
Autor:
Andrea Dörner, Oleg Lynetskiy, Gerhild Euler, Ulf Landmesser, Klaus-Dieter Schlüter, Jacqueline Heger
Publikováno v:
Membranes, Vol 11, Iss 11, p 836 (2021)
Reperfusion is the only feasible therapy following myocardial infarction, but reperfusion has been shown to damage mitochondrial function and disrupt energy production in the heart. Adenine nucleotide translocase 1 (ANT1) facilitates the transfer of
Externí odkaz:
https://doaj.org/article/d4f416391d3e4ca0854d6ee3bdf84e29
Autor:
Paulin Brosinsky, Julia Bornbaum, Björn Warga, Lisa Schulz, Klaus-Dieter Schlüter, Alessandra Ghigo, Emilio Hirsch, Rainer Schulz, Gerhild Euler, Jacqueline Heger
Publikováno v:
Biology, Vol 10, Iss 7, p 670 (2021)
Background: TGFβ1 is a growth factor that plays a major role in the remodeling process of the heart by inducing cardiomyocyte dysfunction and apoptosis, as well as fibrosis thereby restricting heart function. TGFβ1 mediates its effect via the TGFβ
Externí odkaz:
https://doaj.org/article/adcbad6613804c7baf3941df7e3e891b
Publikováno v:
The Scientific World Journal, Vol 2013 (2013)
Nonenzymatic cardiac activities of renin are well described during the last years and contribute either to cardiac-specific effects of the renin-angiotensin-aldosterone-system (RAAS) or to the pharmacological effects of RAAS inhibition. The interacti
Externí odkaz:
https://doaj.org/article/a2ad454f56e24ed19f8405073f10aa34
Autor:
Schlüter, Jonas Knittel, Nadja Itani, Rolf Schreckenberg, Jacqueline Heger, Susanne Rohrbach, Rainer Schulz, Klaus-Dieter
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 1013
Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs). Receptor-dependent effects are specific for seroton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::cf0ece734c9bd705ad953727d8da080f
Autor:
Jacqueline Heger, Tamara Szabados, Paulin Brosinsky, Péter Bencsik, Péter Ferdinandy, Rainer Schulz
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6443
The cardiomyocyte-specific knockout (KO) of monoamine oxidase (MAO)-B, an enzyme involved in the formation of reactive oxygen species (ROS), reduced myocardial ischemia/reperfusion (I/R) injury in vitro. Because sex hormones have a strong impact on M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f244f878389759948cd7840769ab7958
Autor:
Christine Hirschhäuser, Luc Leybaert, Paul D. Lampe, Rainer Schulz, Alessio Lissoni, Klaus-Dieter Schlüter, Kerstin Boengler, Philipp Maximilian Görge, Jacqueline Heger
Publikováno v:
Basic Research in Cardiology
BASIC RESEARCH IN CARDIOLOGY
BASIC RESEARCH IN CARDIOLOGY
Myocardial connexin 43 (Cx43) forms gap junctions and hemichannels, and is also present within subsarcolemmal mitochondria. The protein is phosphorylated by several kinases including mitogen-activated protein kinase (MAPK), protein kinase C (PKC), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4293e0442ad7bf376d227819c1f787
https://doi.org/10.1007/s00395-021-00861-z
https://doi.org/10.1007/s00395-021-00861-z
Autor:
Éva Kenyeres, Gerhild Euler, Joanna Kociszewska, Jacqueline Heger, Péter Ferdinandy, Tamara Szabados, Klaus-Dieter Schlüter, Yvonne Osygus, Péter Bencsik, Rainer Schulz, Rolf Schreckenberg, Fabian Locquet
Publikováno v:
Cardiovascular Drugs and Therapy
Purpose Matrix metalloproteinases (MMPs) are identified as modulators of the extracellular matrix in heart failure progression. However, evidence for intracellular effects of MMPs is emerging. Pro- and anti-hypertrophic cardiac effects are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7052f07ba067cac32bcb8d052bc4db8c
https://pubmed.ncbi.nlm.nih.gov/33400052
https://pubmed.ncbi.nlm.nih.gov/33400052
Autor:
Mariana S. Parahuleva, Gerhild Euler, Julian Kreutz, Wolfram Grimm, Sarah Bühler, Jens Kockskämper, Anna Scherer, Jacqueline Heger, Rainer Schulz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9095, p 9095 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences
Volume 21
Issue 23
Background: Cardiac-specific JDP2 overexpression provokes ventricular dysfunction and atrial dilatation in mice. We performed in vivo studies on JDP2-overexpressing mice to investigate the impact of JDP2 on the predisposition to spontaneous atrial fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca570e6dc85d162e90168cc5f279258d
https://www.mdpi.com/1422-0067/21/23/9095
https://www.mdpi.com/1422-0067/21/23/9095
Autor:
Gerhild Euler, Jacqueline Heger
Publikováno v:
Cardiovascular Research. 115:1257-1259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3693f3463abdc4978de337a7526860b
https://doi.org/10.1093/cvr/cvz079
https://doi.org/10.1093/cvr/cvz079