Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jacqueline H Enzlin"'
Autor:
Anwaar Ahmad, Jacqueline H Enzlin, Nikhil R Bhagwat, Nils Wijgers, Anja Raams, Esther Appledoorn, Arjan F Theil, Jan H J Hoeijmakers, Wim Vermeulen, Nicolaas G J Jaspers, Orlando D Schärer, Laura J Niedernhofer
Publikováno v:
PLoS Genetics, Vol 6, Iss 3, p e1000871 (2010)
Xeroderma pigmentosum (XP) is caused by defects in the nucleotide excision repair (NER) pathway. NER removes helix-distorting DNA lesions, such as UV-induced photodimers, from the genome. Patients suffering from XP exhibit exquisite sun sensitivity,
Externí odkaz:
https://doaj.org/article/23d8c4741f94406fa1db9037dc83848e
Autor:
Anderson T. Wang, Jacqueline H. Enzlin, Lonnie P. Swift, N.A. Burgess-Brown, Opher Gileadi, Peter J. McHugh, Blanka Sengerová, Janet M. Hartley, John A. Hartley, Konstantinos Kiakos, Christopher J. Schofield, Emma Cattell, Takabumi Inagawa
Publikováno v:
Genes & Development. 25:1859-1870
One of the major DNA interstrand cross-link (ICL) repair pathways in mammalian cells is coupled to replication, but the mechanistic roles of the critical factors involved remain largely elusive. Here, we show that purified human SNM1A (hSNM1A), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87158faf132da5bdc18a4529e5eb96a
https://doi.org/10.1101/gad.15699211
https://doi.org/10.1101/gad.15699211
Autor:
Jacqueline H. Enzlin, Adebanke F. Fagbemi, Giuseppina Giglia-Mari, Wim Vermeulen, Stuart G. Clarkson, Lidija Staresincic, Audrey M. Gourdin, Isabelle Dunand-Sauthier, Orlando D. Schärer, Nils Wijgers
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2009, 28 (8), pp.1111-1120. ⟨10.1038/emboj.2009.49⟩
EMBO Journal, Vol. 28, No 8 (2009) pp. 1111-1120
EMBO Journal, 28(8), 1111-1120. Wiley-Blackwell
EMBO Journal, EMBO Press, 2009, 28 (8), pp.1111-1120. ⟨10.1038/emboj.2009.49⟩
EMBO Journal, Vol. 28, No 8 (2009) pp. 1111-1120
EMBO Journal, 28(8), 1111-1120. Wiley-Blackwell
Nucleotide excision repair (NER) requires the coordinated sequential assembly and actions of the involved proteins at sites of DNA damage. Following damage recognition, dual incision 5' to the lesion by ERCC1-XPF and 3' to the lesion by XPG leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272338a7bb4b863e64e94c3bd36259ba
https://doi.org/10.1038/emboj.2009.49
https://doi.org/10.1038/emboj.2009.49
Publikováno v:
The EMBO Journal. 21:2045-2053
XPF-ERCC1 is a structure-specific endonuclease involved in nucleotide excision repair, interstrand crosslink repair and homologous recombination. So far, it has not been shown experimentally which subunit of the heterodimer harbors the nuclease activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7949d38267974214908f53005e72008
https://doi.org/10.1093/emboj/21.8.2045
https://doi.org/10.1093/emboj/21.8.2045
Autor:
Tom Owen-Hughes, Ying Liu, Jacqueline H. Enzlin, Seiki Hirano, Nicola Wiechens, Diana Huttner, Werner Streicher, Ian D. Hickson, Erich A. Nigg, Lily Hui-Ching Wang, Andreas S. Biebricher, Gijs J.L. Wuite, Erwin J.G. Peterman
Publikováno v:
Biebricher, A S, Hirano, S, Enzlin, J, Wiechens, N, Streicher, W W, Huttner, D, Wang, L H C, Nigg, E A, Owen-Hughes, T, Liu, Y, Peterman, E J G, Wuite, G J L & Hickson, I D 2013, ' PICH: a DNA translocase specially adapted for processing anaphase bridge DNA ', Molecular Cell, vol. 51, no. 5, pp. 691-701 . https://doi.org/10.1016/j.molcel.2013.07.016
Molecular Cell, 51(5), 691-701. Cell Press
Molecular Cell
Molecular Cell, 51(5), 691-701. Cell Press
Molecular Cell
The Plk1-interacting checkpoint helicase (PICH) protein localizes to ultrafine anaphase bridges (UFBs) in mitosis alongside a complex of DNA repair proteins, including the Bloom's syndrome protein (BLM). However, very little is known about the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb973c5a7ad19ea5903d101d834a8a8c
https://research.vu.nl/en/publications/4f1f8ccd-682d-406f-b5de-93d8f46ed7c0
https://research.vu.nl/en/publications/4f1f8ccd-682d-406f-b5de-93d8f46ed7c0
Autor:
Wim Vermeulen, Anwaar Ahmad, Anja Raams, Jacqueline H. Enzlin, Nicolaas G. J. Jaspers, Nils Wijgers, Orlando D. Schärer, Arjan F. Theil, Esther Appledoorn, Nikhil R. Bhagwat, Laura J. Niedernhofer, Jan H.J. Hoeijmakers
Publikováno v:
PLoS Genetics
PLoS Genetics (print), 6(3). Public Library of Science
PLoS Genetics, Vol 6, Iss 3, p e1000871 (2010)
PLoS Genetics (print), 6(3). Public Library of Science
PLoS Genetics, Vol 6, Iss 3, p e1000871 (2010)
Xeroderma pigmentosum (XP) is caused by defects in the nucleotide excision repair (NER) pathway. NER removes helix-distorting DNA lesions, such as UV–induced photodimers, from the genome. Patients suffering from XP exhibit exquisite sun sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fffb0b6a47125cd098fad97295aa9b
Autor:
Jérôme Auriol, Jacqueline H. Enzlin, Diane Forget, Frédéric Coin, Jean-Marc Egly, Angels Tapias, Benoit Coulombe, Orlando D. Schärer
In response to genotoxic attacks, cells activate sophisticated DNA repair pathways such as nucleotide excision repair (NER), which consists of damage removal via dual incision and DNA resynthesis. Using permanganate footprinting as well as highly pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837705dc4b279f9f937169b31312cca0
https://europepmc.org/articles/PMC4494833/
https://europepmc.org/articles/PMC4494833/
Autor:
Meindert H. Lamers, Titia K. Sixma, Ganesh Natrajan, Jacqueline H. Enzlin, Herrie H.K. Winterwerp, Anastassis Perrakis
Publikováno v:
Nucleic acids research. 31(16)
We have refined a series of isomorphous crystal structures of the Escherichia coli DNA mismatch repair enzyme MutS in complex with G:T, A:A, C:A and G:G mismatches and also with a single unpaired thymidine. In all these structures, the DNA is kinked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce5294f6214c7fe391ebb41e981efba
https://pubmed.ncbi.nlm.nih.gov/12907723
https://pubmed.ncbi.nlm.nih.gov/12907723
Autor:
Niels de Wind, Jacqueline H. Enzlin, Meindert H. Lamers, Herrie H.K. Winterwerp, Anastassis Perrakis, Titia K. Sixma
Publikováno v:
Nature. 407(6805)
DNA mismatch repair ensures genomic integrity on DNA replication. Recognition of a DNA mismatch by a dimeric MutS protein initiates a cascade of reactions and results in repair of the newly synthesized strand; however, details of the molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061947b48e1c8b0e08942a0507039302
https://pubmed.ncbi.nlm.nih.gov/11048703
https://pubmed.ncbi.nlm.nih.gov/11048703
Autor:
Andreas S. Biebricher, Gijs J.L. Wuite, Jacqueline H. Enzlin, Seiki Hirano, Ian D. Hickson, Erwin J.G. Peterman
Publikováno v:
Biophysical Journal, 104(2), 540A-540A. Biophysical Society
Biebricher, A S, Hirano, S, Enzlin, J, Peterman, E J G, Hickson, I & Wuite, G J L 2013, ' PICH: A DNA Translocase Essential for Resolving Anaphase Bridged DNA ', Biophysical Journal, vol. 104, no. 2, pp. 540A-540A . https://doi.org/10.1016/j.bpj.2012.11.2992
Biebricher, A S, Hirano, S, Enzlin, J, Peterman, E J G, Hickson, I & Wuite, G J L 2013, ' PICH: A DNA Translocase Essential for Resolving Anaphase Bridged DNA ', Biophysical Journal, vol. 104, no. 2, pp. 540A-540A . https://doi.org/10.1016/j.bpj.2012.11.2992
PICH (PLK1-Interacting Checkpoint Helicase) is a recently identified member of the RAD54 subgroup of SNF2 family proteins. PICH localizes to so-called ultra-fine anaphase bridges (UFBs) in mitosis alongside a multi-protein complex of DNA repair prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e0b43cb00af5319ffc91d3e89522b1
https://doi.org/10.1016/j.bpj.2012.11.2992
https://doi.org/10.1016/j.bpj.2012.11.2992