Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jacqueline Gürke"'
Autor:
Jacqueline Gürke, Frank Hirche, René Thieme, Elisa Haucke, Maria Schindler, Gabriele I Stangl, Bernd Fischer, Anne Navarrete Santos
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127465 (2015)
During pregnancy an adequate amino acid supply is essential for embryo development and fetal growth. We have studied amino acid composition and branched chain amino acid (BCAA) metabolism at day 6 p.c. in diabetic rabbits and blastocysts. In the plas
Externí odkaz:
https://doaj.org/article/a0e2363501344e5bb4bba085f57a2089
Autor:
Jacqueline Gürke, Maria Schindler, Elisa Haucke, Katarzyna J. Grybel, Anne Navarrete Santos, Tom Seeling, S. Mareike Pendzialek, Andreas Simm, Alexander Navarrete Santos
Publikováno v:
Reproduction in Domestic Animals. 54:4-11
In a diabetic pregnancy, an altered maternal metabolism led to increased formation of reactive α-dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) in the reproductive organs and embryos. The enzyme glyoxalase (GLO) 1 detoxifies reactive α-di
Autor:
Bernd Fischer, Elen Gocza, Katarzyna J. Grybel, Anne Navarrete Santos, Jacqueline Gürke, Julia M. Knelangen, Maria Schindler, S. Mareike Pendzialek
Publikováno v:
Molecular and Cellular Endocrinology. 480:167-179
MicroRNAs are promising biological markers for prenatal diagnosis. They regulate placental development and are present in maternal plasma. Maternal metabolic diseases are major risk factors for placental deterioration. We analysed the influence of a
Autor:
Maria Schindler, Regine Heller, Jacqueline Gürke, Katrin Spengler, Tom P. Fleming, Bernd Fischer, S. Mareike Pendzialek, Anne Navarrete Santos, Katarzyna J. Grybel, René Thieme
Publikováno v:
REPRODUCTION. 151:465-476
The mammalian target of rapamycin complex 1 (mTORC1) is known to be a central cellular nutrient sensor and master regulator of protein metabolism; therefore, it is indispensable for normal embryonic development. We showed previously in a diabetic pre
Autor:
Bernd, Fischer, Maria, Schindler, S, Mareike Pendzialek, Jacqueline, Gürke, Elisa, Haucke, Katarzyna Joanna, Grybel, René, Thieme, Anne Navarrete, Santos
Publikováno v:
Advances in experimental medicine and biology. 1014
Maternal metabolic diseases such as diabetes mellitus with diabetogenic hypoinsulinemia and hyperglycemia change periconceptional developmental conditions in utero. In preimplantation rabbit embryos, all major metabolic pathways are affected. Alterat
Autor:
Elisa Haucke, Katarzyna J. Grybel, S. Mareike Pendzialek, Maria Schindler, Jacqueline Gürke, Anne Navarrete Santos, René Thieme, Bernd Fischer
Publikováno v:
Periconception in Physiology and Medicine ISBN: 9783319624129
Maternal metabolic diseases such as diabetes mellitus with diabetogenic hypoinsulinemia and hyperglycemia change periconceptional developmental conditions in utero. In preimplantation rabbit embryos, all major metabolic pathways are affected. Alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a97b310127fc1a910556876f5ad84167
https://doi.org/10.1007/978-3-319-62414-3_6
https://doi.org/10.1007/978-3-319-62414-3_6
Autor:
Andreas Simm, Alexander Navarrete Santos, Marcus A. Glomb, Anne Navarrete Santos, Jacqueline Gürke, Elisa Haucke, Maria Schindler, Bernd Fischer, Christian Henning
Publikováno v:
REPRODUCTION. 148:169-178
Diabetes mellitus (DM) during pregnancy is one of the leading causes of perinatal morbidity and birth defects. The mechanism by which maternal hyperglycemia, the major teratogenic factor, induces embryonic malformations remains unclear. Advanced glyc
Maternal Diabetes Leads to Unphysiological High Lipid Accumulation in Rabbit Preimplantation Embryos
Autor:
Alexander Navarrete Santos, Maria Schindler, Anne Navarrete Santos, Stefanie Seyring, Torsten Plösch, Bernd Fischer, Elisa Haucke, Mareike Pendzialek, Jacqueline Gürke, Julia M. Knelangen
Publikováno v:
Endocrinology, 155(4), 1498-1509. ENDOCRINE SOC
According to the “developmental origin of health and disease” hypothesis, the metabolic set points of glucose and lipid metabolism are determined prenatally. In the case of a diabetic pregnancy, the embryo is exposed to higher glucose and lipid c
Autor:
Maria Schindler, Katarzyna J. Grybel, Tom Seeling, Anne Navarrete Santos, Bernd Fischer, Mareike Pendzialek, Jacqueline Gürke
Publikováno v:
Human Reproduction (Oxford, England)
STUDY QUESTION How does a maternal diabetic hyperadiponectineamia affect signal transduction and lipid metabolism in rabbit preimplantation blastocysts? SUMMARY ANSWER In a diabetic pregnancy increased levels of adiponectin led to a switch in embryon
Autor:
A. Navarrete Santos, Katarzyna J. Grybel, Maria Schindler, Tom Seeling, Bernd Fischer, S.M. Pendzialek, Jacqueline Gürke
Publikováno v:
Diabetologie und Stoffwechsel. 11