Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jacqueline Farinha Shimizu"'
Autor:
Alexandre Borin, Laís D. Coimbra, Karina Bispo-dos-Santos, Fabrício F. Naciuk, Marina Fontoura, Camila L. Simeoni, Giovanni F. Gomes, Mariene R. Amorim, Humberto D. Gravina, Jacqueline Farinha Shimizu, Amanda S. C. Passos, Isadora M. de Oliveira, Ana Carolina de Carvalho, Alisson Campos Cardoso, Pierina L. Parise, Daniel A. Toledo-Teixeira, Giuliana E. Sotorilli, Gabriela F. Persinoti, Ingra Morales Claro, Ester C. Sabino, Marcos R. Alborghetti, Silvana A. Rocco, Kleber G. Franchini, William M. de Souza, Paulo S. L. Oliveira, Thiago M. Cunha, Fabiana Granja, José Luiz Proença-Módena, Daniela B.B. Trivella, Marjorie Bruder, Artur T. Cordeiro, Rafael Elias Marques
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1031-1048 (2022)
The ongoing COVID-19 pandemic caused a significant loss of human lives and a worldwide decline in quality of life. Treatment of COVID-19 patients is challenging, and specific treatments to reduce COVID-19 aggravation and mortality are still necessary
Externí odkaz:
https://doaj.org/article/72c2c6f47ab64b468b8394b05cb4b8c0
Autor:
Gustavo Fernando Mercaldi, Eduardo Henrique Salviano Bezerra, Fernanda Aparecida Heleno Batista, Celisa Caldana Costa Tonoli, Adriana Santos Soprano, Jacqueline Farinha Shimizu, Alice Nagai, Jaqueline Cristina da Silva, Helder Veras Ribeiro Filho, Jéssica do Nascimento Faria, Marcos Guilherme da Cunha, Ana Carolina Mattos Zeri, Andrey Fabricio Ziem Nascimento, José Luiz Proenca-Modena, Marcio Chaim Bajgelman, Silvana Aparecida Rocco, Paulo Sérgio Lopes-de-Oliveira, Artur Torres Cordeiro, Marjorie Bruder, Rafael Elias Marques, Mauricio Luis Sforça, Kleber Gomes Franchini, Celso Eduardo Benedetti, Ana Carolina Migliorini Figueira, Daniela Barretto Barbosa Trivella
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The nucleocapsid (N) protein plays critical roles in coronavirus genome transcription and packaging, representing a key target for the development of novel antivirals, and for which structural information on ligand binding is scarce. We used
Externí odkaz:
https://doaj.org/article/82850da7d4af470d8e0f50ddce822904
Autor:
Giuliana Eboli Sotorilli, Humberto Doriguetto Gravina, Ana Carolina de Carvalho, Jacqueline Farinha Shimizu, Marina Alves Fontoura, Talita Diniz Melo-Hanchuk, Artur Torres Cordeiro, Rafael Elias Marques
Publikováno v:
Viruses, Vol 15, Iss 12, p 2416 (2023)
St. Louis encephalitis virus (SLEV) is a neglected mosquito-borne Flavivirus that may cause severe neurological disease in humans and other animals. There are no specific treatments against SLEV infection or disease approved for human use, and drug r
Externí odkaz:
https://doaj.org/article/c234a3b208bc4d74b360b91207ddd778
Autor:
Igor Andrade Santos, Jacqueline Farinha Shimizu, Débora Moraes de Oliveira, Daniel Oliveira Silva Martins, Léia Cardoso-Sousa, Adélia Cristina Oliveira Cintra, Victor Hugo Aquino, Suely Vilela Sampaio, Nilson Nicolau-Junior, Robinson Sabino-Silva, Andres Merits, Mark Harris, Ana Carolina Gomes Jardim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies. In this context, sn
Externí odkaz:
https://doaj.org/article/95497c7a0e3b4bd78a66109113693206
Autor:
Stephanie Wutke Oliveira, Leia Cardoso-Sousa, Renata Pereira Georjutti, Jacqueline Farinha Shimizu, Suely Silva, Douglas Carvalho Caixeta, Marco Guevara-Vega, Thúlio Marquez Cunha, Murillo Guimarães Carneiro, Luiz Ricardo Goulart, Ana Carolina Gomes Jardim, Robinson Sabino-Silva
Publikováno v:
Diagnostics, Vol 13, Iss 8, p 1443 (2023)
Zika virus (ZIKV) diagnosis is currently performed through an invasive, painful, and costly procedure using molecular biology. Consequently, the search for a non-invasive, more cost-effective, reagent-free, and sustainable method for ZIKV diagnosis i
Externí odkaz:
https://doaj.org/article/87d8da3d1ead4b15bc4bacee0694d62a
Autor:
Laís D. Coimbra, Alexandre Borin, Marina Fontoura, Humberto D. Gravina, Alice Nagai, Jacqueline Farinha Shimizu, Karina Bispo-dos-Santos, Fabiana Granja, Paulo S. L. Oliveira, Kleber G. Franchini, Kirandeep Samby, Marjorie Bruder, José Luiz Proença-Módena, Daniela B. B. Trivella, Juliana H. C. Smetana, Artur T. Cordeiro, Rafael Elias Marques
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Until December 2021, the COVID-19 pandemic has caused more than 5.5 million deaths. Vaccines are being deployed worldwide to mitigate severe disease and death, but continued transmission and the emergence of SARS-CoV-2 variants indicate that specific
Externí odkaz:
https://doaj.org/article/a5ef3494e053423bab15254c1229c102
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide. There is no effective vaccine for prevention of HCV infection; however, a numbe
Externí odkaz:
https://doaj.org/article/0a5a36e8f83f4d0ab7644f1416068c60
Autor:
Marielena Vogel Saivish, Gabriela de Lima Menezes, Roosevelt Alves da Silva, Marina Alves Fontoura, Jacqueline Farinha Shimizu, Gislaine Celestino Dutra da Silva, Igor da Silva Teixeira, Natalia Franco Bueno Mistrão, Victor Miranda Hernandes, Paula Rahal, Lívia Sacchetto, Carolina Colombelli Pacca, Rafael Elias Marques, Maurício Lacerda Nogueira
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7504
Zika virus (ZIKV) has re-emerged in recent decades, leading to outbreaks of Zika fever in Africa, Asia, and Central and South America. Despite its drastic re-emergence and clinical impact, no vaccines or antiviral compounds are available to prevent o
Autor:
Jacqueline Farinha Shimizu, Carina Machado Pereira, Cintia Bittar, Mariana Nogueira Batista, Guilherme Rodrigues Fernandes Campos, Suely da Silva, Adélia Cristina Oliveira Cintra, Carsten Zothner, Mark Harris, Suely Vilela Sampaio, Victor Hugo Aquino, Paula Rahal, Ana Carolina Gomes Jardim
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187857 (2017)
Hepatitis C virus (HCV) is one of the main causes of liver disease and transplantation worldwide. Current therapy is expensive, presents additional side effects and viral resistance has been described. Therefore, studies for developing more efficient
Externí odkaz:
https://doaj.org/article/907aba9c846c44c48af3451eee3bc17c
Autor:
Jacqueline Farinha Shimizu, Shiraz Feferbaum-Leite, Igor Andrade Santos, Daniel Oliveira Silva Martins, Natalie J. Kingston, Mona Shegdar, Carsten Zothner, Suely Vilela Sampaio, Mark Harris, Nicola J. Stonehouse, Ana Carolina Gomes Jardim
Publikováno v:
International Journal of Biological Macromolecules. 241:124519