Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jacqueline E. Mermoud"'
Autor:
Parysatis Sachs, Dong Ding, Philipp Bergmaier, Boris Lamp, Christina Schlagheck, Florian Finkernagel, Andrea Nist, Thorsten Stiewe, Jacqueline E. Mermoud
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Tight regulation of retrotransposons such as endogenous retroviruses (ERVs) is essential for genome and transcriptome integrity. Here, the authors show that the ATPase function of the chromatin remodeler SMARCAD1 facilitates the binding of KAP1 to ER
Externí odkaz:
https://doaj.org/article/0e710344df08499391e740770a34e858
Autor:
Jacqueline E, Mermoud
Publikováno v:
Genes. 13(12)
The RNA methylation of adenosine at the N6-position (m
Publikováno v:
Stem Cell Epigenetics ISBN: 9780128140857
Endogenous retroviruses (ERVs) represent abundant retrotransposon families that have coevolved in the mammalian genome for millions of years. Although long considered junk DNA, it is becoming increasingly evident that ERVs are likely to play importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a930a90c79483dc78f0a14186d2fbf1
https://doi.org/10.1016/b978-0-12-814085-7.00007-6
https://doi.org/10.1016/b978-0-12-814085-7.00007-6
Autor:
Sergi Aranda, Orazio Angelo Arcidiacono, Jerome Artus, Eva Bártová, Stephanie L. Battle, Danny Bavli, Alva Biran, Miguel R. Branco, Raul Bardini Bressan, Nicolò Caporale, Luciano Di Croce, Camille Dion, Inma Gonzalez, R. David Hawkins, Chen Kozulin, Jana Krejčí, Soňa Legartová, Harry G. Leitch, Alejandro Lopez-Tobon, Jacqueline E. Mermoud, Eran Meshorer, Pablo Navarro, Nick D.L. Owens, Angeliki Platania, Steven M. Pollard, Raymond A. Poot, Oren Ram, Sharon Schlesinger, Tom Sexton, Lenka Stixova, Giuseppe Testa, Sebastiano Trattaro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a58e6e090c1fbe85b29c29c4952c419a
https://doi.org/10.1016/b978-0-12-814085-7.09990-6
https://doi.org/10.1016/b978-0-12-814085-7.09990-6
Autor:
Jacqueline E. Mermoud, Tamina Rückert, Mike R. Dekker, Parysatis Sachs, Marius Klangwart, Raymond A. Poot, Dong Ding, Philipp Bergmaier, Nora Bartels, Jeroen Demmers
Publikováno v:
Journal of Biological Chemistry, 293(8), 2711-2724. American Society for Biochemistry and Molecular Biology Inc.
Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Accordingly, ATP-dependent chromatin remodeling complexes are important regulators of ESC homeostasis. Dep
Autor:
Christina Schlagheck, Andrea Nist, Boris Lamp, Thorsten Stiewe, Florian Finkernagel, Philipp Bergmaier, Jacqueline E. Mermoud, Dong Ding, Parysatis Sachs
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
Endogenous retroviruses (ERVs) can confer benefits to their host but present a threat to genome integrity if not regulated correctly. Here we identify the SWI/SNF-like remodeler SMARCAD1 as a key factor in the control of ERVs in embryonic stem cells.
Autor:
Vladimir A. Snetkov, Marcus Hughes, Colin Dingwall, Sebastian Trousil, Jacqueline E. Mermoud, Ruth Sarah Rose
Publikováno v:
Journal of Neurochemistry. 114:832-842
Epidemiological studies have shown an association between statin use and a decreased risk of dementia. However, the mechanism by which this beneficial effect is brought about is unclear. In the context of Alzheimer's disease, at least three possibili
Autor:
Thomas Jenuwein, Neil Brockdorff, Bilyana C. Popova, Jacqueline E. Mermoud, Antoine H.F.M. Peters
Publikováno v:
Current Biology. 12:247-251
In female mammals, a single X chromosome is stably and heritably silenced early in embryogenesis [1]. The inactive X is characterized by asynchronous DNA replication [2, 3] and epigenetic chromatin modifications, including DNA methylation [4], histon
Autor:
Jacqueline E. Mermoud, Anne McLaren, Kathy Hilton, Neil Brockdorff, John R. Pehrson, M. Azim Surani, Tatyana B. Nesterova
Publikováno v:
Differentiation. 69:216-225
The molecular mechanism underlying X chromosome inactivation in female mammals involves the non-coding RNAs Xist and its antisense partner Tsix. Prior to X inactivation, these RNAs are transcribed in an unstable form from all X chromosomes, both in t
Publikováno v:
Cell cycle (Georgetown, Tex.). 10(23)
Disruption of chromatin organization during replication poses a major challenge to the maintenance and integrity of genome organization. It creates the need to accurately reconstruct the chromatin landscape following DNA duplication but there is litt